TY - JOUR T1 - Böbrek fonksiyon bozukluğu olan hastalarda endoskopik üreter taşı cerrahisinin glomerüler filtrasyon hızı üzerine etkisi TT - Effect of endoscopic ureteral stone surgery on glomerular filtration rate in patients with renal impairment AU - Caniklioğlu, Mehmet AU - Selmi, Volkan AU - Sarı, Sercan AU - Öztekin, Ünal AU - Özkaya, Muharrem AU - Işıkay, Levent PY - 2022 DA - August Y2 - 2022 DO - 10.17944/mkutfd.930695 JF - The Medical Journal of Mustafa Kemal University JO - mkutfd PB - Hatay Mustafa Kemal University WT - DergiPark SN - 2149-3103 SP - 107 EP - 112 VL - 13 IS - 46 LA - tr AB - Amaç: Ameliyat öncesi tahmini glomerüler filtrasyon oranları (eGFR) düzeyi 60 ml/dk’nın altında olan bir hasta grubunda üst üreter taşlarında üreterorenoskopi (URS) ya da fleksible üreterorenoskopi (fURS) öncesi ve sonrası eGFR değişimini ve buna etki eden faktörleri değerlendirmeyi amaçladık.Yöntem: Üst üreter taşı nedeniyle ameliyat planlanan ve kısa MDRD formülü ile hesaplanan ameliyat öncesi eGFR 60 ml/dk’nın altında olan 32 hasta çalışmaya dahil edildi. Hastaların ameliyat öncesi ve sonrası eGFR değişimlerine etki eden faktörler çoklu lineer regresyon analizi ile karşılaştırıldı. Bulgular: Düşük renal rezervli hastalar da tedavi sonrasında renal fonksiyonlar açısından iyi düzeyde bir iyileşme gösterdiler. Yaş, beden kitle indeksi (BKİ) ve preoperatif eGFR anlamlı düzeyde postoperatif eGFR’yi etkiliyordu (p KW - Endoskopik üreter taşı tedavisi KW - Üreterorenoskopi KW - Retrograd intrarenal cerrahi KW - Glomerüler filtrasyon hızı KW - Düşük renal rezerv KW - Kronik böbrek yetmezliği N2 - Objective: We aimed to evaluate the estimated glomerular filtration rates (eGFR) change in upper ureteral stones before and after ureterorenoscopy (URS) or flexible ureterorenoscopy (fURS) in a patient group with preoperative eGFR level below 60 ml / min and the factors affecting it.Methods: Thirty-two patients who were scheduled for surgery due to upper ureteral stones and whose preoperative eGFR that calculated with the short MDRD formula, below 60 mL / min were included in the study. Factors that affect preoperative and postoperative eGFR changes of the patients were investigated by multiple linear regression analysis.Results: Patients with low renal reserve also showed a good improvement in renal function after treatment. Age, body mass index (BMI) and preoperative eGFR significantly affected postoperative eGFR (p CR - Knoll T, Alken P. Looking back on 50 years of stone treatment. Aktuelle Urol. 2019;50:157–65. https://doi.org/10.1055/a-0828-9936 CR - Zhe M, Hang Z. Nephrolithiasis as a risk factor of chronic kidney disease: a meta-analysis of cohort studies with 4,770,691 participants. Urolithiasis. 2017;45:441–8. https://doi.org/10.1007/s00240-016-0938-x CR - Inker LA, Astor BC, Fox CH, Isakova T, Lash JP, Peralta CA, et al. KDOQI Commentary KDOQI US Commentary on the 2012 KDIGO Clinical Practice Guideline for the Evaluation and Management of CKD. 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