@article{article_933050, title={Evaluation of Etiological Factors Causing Hypereosinophilia in Children}, journal={Türkiye Çocuk Hastalıkları Dergisi}, volume={15}, pages={373–378}, year={2021}, DOI={10.12956/tchd.933050}, author={Külhaş Çelik, İlknur and Büyüktiryaki, Betül and Gültekin Açıkgöz, Filiz and Erkan, Mehmet Orhan and Guzelkucuk, Zeliha and Özbek, Namık Yaşar and Toyran, Muge and Dibek Mısırlıoğlu, Emine and Civelek, Ersoy}, keywords={hypereosinophilia, childhood, parasitic infections, allergic diseases, immunologic diseases}, abstract={<p> <b>Objective: </b> Patients with persistent eosinophilia may have many conditions ranging from relatively benign diseases such as parasitic serious infections to life-threatening serious diseases. We aimed to determine the etiological causes of hypereosinophilia in children.  </p> <p> <b> Material and Methods: </b> Patients under 18 years of age who had complete blood counts in Ankara Child Health and Diseases Hematology Oncology Training and Research Hospital’s pediatric clinics between January 2013-January 2016 were retrospectively analyzed. Hypereosinophilia was defined as having at least two peripheral blood absolute eosinophil counts greater than or equal to 1500/mm3.The results of the examinations and diagnoses when the patients were detected with hypereosinophilia were recorded from the hospital records. </p> <p> <b>Results: </b>Three hundred and forty patients who underwent complete blood count were found to have hypereosinophilia. Seventy patients whose file records could not be accessed were excluded from the study. Two-hundred seventy patients (56% male) with a median age of 5 (IQR:1-12) years were included in our study. When the diagnoses of patients were examined, 48 (17.8%) had allergic diseases, 21 (7.8%) had immunodeficiency, 14 (5.2%) had parasitic disease. 15 (5.5%) had tumor, 4 (1.5%) had leukemia, 2 (0.7%) had hypereosinophilic syndrome, 2 (0.7%) had adrenal insufficiency and 2 (0.7%) had burn. Ninety-nine (36.7%) patients were found to use medication for any disease (acute or chronic). As a result of the
examinations performed in 63 (23.3%) patients, it was found that there was no reason to explain hypereosinophilia. </p> <p> <b>Conclusion: </b>The number of eosinophils may increase in many conditions. The cause of increase in eosinophil may not always be found.
Further studies are needed on the long-term prognosis of these patients. </p>}, number={5}, publisher={T.C. Sağlık Bakanlığı Ankara Şehir Hastanesi}