TY - JOUR T1 - Nd: YAG Lazer Kapsülotominin Göz İçi Basınç ve Kornea Endoteli Üzerine Erken Dönemde Etkisi TT - Effect of Nd: YAG Laser Capsulotomy on Intraocular Pressure and Corneal Endothelium in the Early Period AU - Keleş, Ali AU - Karaman, Süleyman PY - 2021 DA - July DO - 10.53394/akd.964842 JF - Akdeniz Tıp Dergisi JO - Akd Tıp D PB - Akdeniz University WT - DergiPark SN - 2687-2781 SP - 220 EP - 224 VL - 7 IS - 2 LA - tr AB - Amaç: Neodymium: yttrium-aluminum garnet (Nd: YAG) lazer kapsülotomi olgularında, işlemsonrası erken dönemde göz içi basınç (GİB) ve kornea endoteli morfolojisindeki değişimi araştırmak.Gereç ve Yöntemler: Çalışmaya arka kapsül kesafeti olan 58 hastanın 74 gözü dahil edildi.Hastaların başlangıç GİB değerleri Nd: YAG lazer kapsülotomiden sonraki ilk saat ve ilk ay değerleriile karşılaştırıldı. Ayrıca endotel hücre yoğunluğu (EHY), hücre alanının varyasyon katsayısı (VK),hekzagonal hücrelerin yüzdesi (HHY) ve merkezi kornea kalınlığı (MKK) ölçümleri spekülermikroskopi ile analiz edildi ve karşılaştırıldı.Bulgular: Hastaların yaş ortalaması 66,84±9,51 yıldı. Ortalama GİB değeri lazer öncesi ile lazersonrası birinci saatte ve birinci ayda benzerdi (sırasıyla p=0,361 ve p=0,516). Ortalama EHY lazeröncesine (2025,73±470,18 hücre/mm2) göre lazer sonrası birinci saatte (1968,31±465,27 hücre/mm2)ve birinci ayda (1984,72±453,55 hücre/mm2) anlamlı olarak azaldı (sırasıyla p=0,001 ve p=0,021).Lazer öncesi, lazer sonrası birinci saatte ve lazer sonrası birinci ayda ortalama VK, HHY ve MKKdeğerleri arasında anlamlı farklılık yoktu (p>0,05). Korneal endotel kaybı ile toplam lazer enerjigücü arasında birinci saatte ve birinci ayda anlamlı korelasyon yoktu (sırasıyla r=-0,046, p=0,699 ver=0,134, p=0,257).Sonuç: Nd: YAG lazer kapsülotomi sonrası anlamlı GİB artışı izlenmemiştir. İşlem sonrası tümhastaların anti-glokomatöz tedavi kullanması gerekmemektedir. Lazer sonrası kornea endotel hücresayısında azalma görülmüştür. Dolayısıyla kornea endotel sayısı düşük olan hastalarda bu işlem dahadikkatli uygulanmalıdır. KW - Arka kapsül kesafeti KW - Göz içi basınç KW - Kornea endotel morfolojisi KW - Nd: Yag lazer kapsülotomi N2 - Objective: To investigate the changes in intraocular pressure (IOP) and corneal endothelialmorphology in neodymium: yttrium-aluminum-garnet (Nd: YAG) laser capsulotomy cases in the earlyperiod after the procedure.Material and Methods: Seventy four eyes of 58 patients with posterior capsular opacification wereincluded in the study. The baseline IOP of the patients was compared to the first hour and first-monthvalues after Nd: YAG laser capsulotomy. Also, endothelial cell density (ECD), coefficient of variation(CV), hexagonality rate (HEX), and central corneal thickness (CCT) measurements were analyzed byspecular microscopy and compared.Results: Mean age of the patients was 66.84±9.51 years. Mean IOP value was similar at pre-laser andpost-laser first hour and first month (p=0.361 and p=0.516, respectively). Mean ECD was significantlydecreased at the first hour (1968.31±465.27 cells/mm2) and the first month (1984.72±453.55cells/mm2) after laser compared to pre-laser (2025.73±470.18 cells/mm2), (p=0.001 and p=0.021,respectively). There was no significant difference between the mean CV, HEX, and CCT valuesbefore laser, at the first hour and first month after laser (p>0.05). There was no significant correlationbetween corneal endothelial loss and total laser energy power at the first hour and first month (r=-0.046, p=0.699 and r=0.134, p=0.257, respectively).Conclusion: No significant IOP increase was observed after Nd: YAG laser capsulotomy. Notall patients need to use anti-glaucomatous therapy after the procedure. A decrease in the numberof corneal endothelial cells was seen after laser. Therefore, this procedure should be applied morecarefully in patients with low corneal endothelium count. CR - 1. Auffarth GU, Brezin A, Caporossi A, Lafuma A, Mendicute J, Berdeaux G, Smith AF; European PCO Study Group. Comparison of Nd:YAG capsulotomy rates following phacoemulsification with implantation of PMMA, silicone, or acrylic intra-ocular lenses in four European countries. Ophthalmic Epidemiol 2004; 11: 319–29. CR - 2. Aron-Rosa D, Aron JJ, Griesemann M, Thyzel R. 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Öztürk Y, Göktaş E, Çallı Ü, Çelik Yaprak D, Oral Y, Penbe A. Yoğun Arka Kapsül Kesafeti Olan Hastalarda Nd:YAG Laser Kapsülotomi Sonrası Korneal Endotel Değişiklikleri. Turkiye Klin J Ophthalmol 2019; 28: 75–9. CR - 18. Slomovic AR, Parrish RK 2nd, Forster RK, Cubillas A. Neodymium-YAG Laser Posterior Capsulotomy: Central Corneal Endothelial Cell Density. Arch Ophthalmol 1986; 104: 536–8. UR - https://doi.org/10.53394/akd.964842 L1 - https://dergipark.org.tr/en/download/article-file/1866539 ER -