@article{article_973420, title={Synthesis, Structure and Properties of Novel S-Substituted BIS-1,2,4-Triazoles}, journal={Hacettepe University Journal of the Faculty of Pharmacy}, volume={41}, pages={150–161}, year={2021}, DOI={10.52794/hujpharm.973420}, author={Karpun, Yevhen}, keywords={Keywords: 1, heterocyclic compound, synthesis, fragmentation pathway, 1,2,4-triazole}, abstract={The aim of the work was to describe the method of combining two 1,2,4-triazole systems in a molecule, the alkylation reaction of the thiol group to obtain the previ- ously undiscovered S-derivatives of 1,2,4-triazole and the fragmentation pathway of the substances under hard ionization using gas chromatography-mass spectrom- etry. The structures of the synthesized compounds were confirmed by elemental analysis, 1H and 13C NMR spectroscopy and GC-MS analysis. The characteristic signals for S-alkyl residues were observed in the region typical for aliphatic com- pounds. The fragmentation of molecules was represented by the gradual cleavage of radicals and the opening of the second 1,2,4-triazole heterocycle. <br />}, number={3}, publisher={Hacettepe University}