@article{article_999158, title={SYNTHESIS AND INVESTIGATION OF SUBTITUTED 2-AMINOTHIOPHENES FROM SULPHUR AND ACTIVE ME- HYLENE BEARING NITRILES}, journal={Communications Faculty of Sciences University of Ankara Series B Chemistry and Chemical Engineering}, volume={32}, pages={2–18}, year={1986}, DOI={10.1501/Commub_0000000277}, author={Ertüzün, Vedia}, keywords={SYNTHESIS AND INVESTIGATION, HYLENE BEARING NITRILES, substituent and heteroatom effects}, abstract={Benzyl ■ a - cyano cynnamic acid, a nitrile with active methylene group has been synthesized. The reaction of this compound with sulphur in the presence of diethylamine gave 2-Amino-4,5-dıphenyl-3-cyanothiophene. In addition, a similar compound, 2-amino 4-ethyl-5-methyl-3-cyanothiophene has been obtained from sulphur and malonic acid dinitrile using the same amine as catalyst. The both thiophenes and their Schiff’s bases with salicylaldehyde and [3-Hydroxynaphtaldehyde have been investigated by uv, ir and ’H-nmr spectroscopy and pKa measurements in terms of substituent and heteroatom effects on various characteristics.}, number={01.02}, publisher={Ankara University}