Aim: In this study, it was intended to investigate the effects of alcohol on structures of fetal cerebellar Purkinje cells in semi thin sections.

Materials and method: 12 adult female rats of Sprague-Dawley species were utilized. Control and experiment groups were formed. Rats were made pregnant. Rats in experiment group were administered liquid diet containing 6% alcohol. Cerebellums of infant rats were taken on 6th, 8th and 10th days after birth. Tissue samples were taken to routine electron microscopic procedure and then semi thin sections were examined.

Results: When control and experiment groups were compared, it was determined that development in the experiment group was lesser than the control group.

Conclusion: was determined that liquid diet containing 6% alcohol had toxic effects on Purkinje cells and caused structural alterations in these cells.