A 45 years old patient with acute urticaria table was admitted to hospital and computirezed tomography (CT) determined a 63X65 mm uniloculary cyst hydatid in his left hepatic lobe. The diagnosis was also confirmed with serological and allergic test results. This case report indicates that when when hepatobiliyer system or another organ or system insufficiency symptoms are present, a search for cyst hydatid with CT or uldrasound would be helpful for therapy management.