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Bazı Ormangülü Ballarının Fenolik İçerik Kompozisyonu

Year 2017, Volume: 9 Issue: 2, 40 - 46, 01.12.2017

Hüseyin Şahin Zehra Can Sevgi Kolaylı

Abstract

Ormangülü balı,
ülkemiz coğrafyasında özellikle Karadeniz Bölgesi kıyı kesimlerinde yayılım
gösteren Rhododendron bitki türlerinin kaynaklık ettiği ballardır. Halk
arasında deli bal olarak da bilinen bu bal, içeriğinde grayanotoksinler (GTX)
denilen oldukça aktif toksinleri barındırır ve tüketimi birçok toksikolojik
semptoma sebep olabilir. Toksik etki en çok hipotansiyon ve bradikardi
semptomlarıyla kendini göstermektedir. Ancak bu balların içeriğinde sekonder
metabolitlerin önemli ajanları olan fenolik bileşenlerin de bulunduğu bilinmektedir.
Fenolik bileşenler özellikle antioksidan ve antimikrobiyal gibi etkilerden
sorumlu biyolojik moleküllerdir. Mevcut bu çalışma, Karadeniz Bölgesi’nin bazı
illerinden temin edilen ormangülü ballarındaki fenolik bileşenleri teşhis etmek
amacıyla tasarlanmıştır. Bu amaç doğrultusunda RP-HPLC-DAD ile 17 fenolik
bileşenin kalitatif ve kantitatif analizi gerçekleştirilmiştir. Analiz sonucuna
göre tüm bal örneklerinde p-OH benzoik asit bileşenine (2,351-18,992 µg/g
numune) rastlanmış olup kullanılan standartlar nispetinde major bileşen olarak
değerlendirilmiştir. 

Keywords

Ormangülü balı RP-HPLC-DAD Fenolik bileşen p-OH benzoik asit

References

  • Ahmed, S., Othman, N. H., 2013. Honey as a Potential Natural Anticancer Agent: A Review of Its Mechanisms. Evidence-Based Complementary and Alternative Medicine, 2013, 829070. Doi.org/10.1155/2013/829070
  • Allen K. L., Molan P. C., Reid G. M., 1991. A survey of the antibacterial activity of some New Zealand honeys. Journal of Pharmacy and Pharmacology, 43, 817–822.
  • Al-Waili N. S., 2004. Natural honey lowers plasma glucose, C-reactive protein, homocysteine, and blood lipids in healthy, diabetic, and hyperlipidemic subjects: comparison with dextrose and sucrose. Journal of Medicinal Food, 7,100-107. Doi: 10.1089/109662004322984789
  • Can, Z., Yildiz, O., Sahin, H., Akyuz Turumtay E., Silici S., Kolayli S., 2015. An investigation of Turkish honeys: Their pyhysico-chemical properties, antioxidant capacities and phenolic profiles. Food Chemistry, 180, 133-41. Doi: 10.1016/j.foodchem.2015.02.024
  • Jeddar A., Kharsany A., Ramsaroop U. G., Bhamjee A., Haffejee I. E., Moosa A., 1985. The antibacterial action of honey: an in vitro study. South African Medical Journal, 67, 257-258.
  • Kandil, A., El-Banby, M., Abdel-Wahed, G. K., Abdel-Gawwad, M., Fayez, M., 1987. Curative properties of true floral and false non-floral honeys on induced gastric ulcers. Journal of Drug Research, 17, 103-106.
  • Kurtoğlu, S., 1992. Zehirlenmeler, Teşhis ve Tedavi, Kayseri: Erciyes Ünviversitesi Yayınları, 30, 569-570.
  • Larson-Meyer, D. E., Willis, K. S., Willis, L. M., Austin, K. J., Hart, A. M., Breton, A. B., Alexander, B. M., 2010. Effect of honey versus sucrose on appetite, appetite-regulating hormones, and postmeal thermogenesis. Journal of the American College of Nutrition, 29, 5, 482-493.
  • Louveaux, J., Maurizio, A., Vorwohl, G., 1978. Methods of melissopalynology. Bee World, 59, 139–157.
  • Manuja, R., Sachdeva, S., Jain, A., Chaudhary, J., 2013. A comprehensive review on biological activities of p-hydroxy benzoic acid and its derivatives. International Journal of Pharmaceutical Sciences Review and Research, 20, 109-115.
  • Miniati E., 2007. Assessment of phenolic compounds in biological samples. Phenolics in Biological Samples, 43, 4, 362-368.
  • Oksana, S., Marian, B., Mahendra, R., Hong Bo, S., 2012. Plant phenolic compounds for food, pharmaceutical and cosmetiсs production. Journal of Medicinal Plants Research, 6, 2526-2539.
  • Pamir, F., 1969. Klinik Toksikoloji. Ankara: Ankara Yarı Açık Cezaevi Matbaası, 457-458.
  • Pasupuleti, V. R., Sammugam, L., Ramesh, N., Gan, S. H., 2017. Honey, Propolis, and Royal Jelly: A Comprehensive Review of Their Biological Actions and Health Benefits. Oxidative Medicine and Cellular Longevity, 2017, 1259510. Doi:10.1155/2017/1259510
  • Rani, G. N., Budumuru, R., Bandaru, N. R., 2017. Antimicrobial Activity of Honey with Special Reference to Methicillin Resistant Staphylococcus aureus (MRSA) and Methicillin Sensitive Staphylococcus aureus (MSSA). Journal of Clinical and Diagnostic Research, 11(8), DC05–DC08. Doi: 10.7860/JCDR/2017/30085.10347
  • Rasgele, P., Kekecoglu, M. 2014. Physico-chemical properties of rhododendron honey produced in Turkey. Herba Polonica, 59(3), 88-97. Doi:10.2478/hepo-2013-0019
  • Ruiz-Ruiz, J. C., Matus-Basto, A. J., Acereto-Escoffié, P., Segura-Campos M. R., 2017. Antioxidant and anti-inflammatory activities of phenolic compounds isolated from Melipona beecheii honey, Journal Food and Agricultural Immunology, 28(6), 1424-1437. Doi: 10.1080/09540105.2017.1347148
  • Sahin, H., 2014. Analysis of Grayanotoxin-III (GTX-III) Isoform in rhododendron honeys and its plants by LC-MS/MS, PhD. Thesis, Karadeniz Technical University, The Graduate School of Natural and Applied Sciences, Chemistry Graduate Program, Trabzon, Turkey.
  • Sahin, H., 2016. Honey as an apitherapic product: its inhibitory effect on urease and xanthine oxidase, Journal of Enzyme Inhibition and Medicinal Chemistry, 31:3, 490-494, Doi: 10.3109/14756366.2015.1039532
  • Sahin, H., Akyuz Turumtay, E., Yildiz, O., Kolayli, S., 2015. Grayanotoxin-III detection and antioxidant activity of mad honey. International Journal of Food Properties, 18(12), 2665-2674. Doi: 10.1080/10942912.2014.999866.
  • Silici, S., Doğan, Z., Sahin, H., Atayoglu, T., Yakan, B., 2016. Acute effects of grayanotoxin in rhododendron honey on kidney functions in rats. Environmental Science and Pollution Research, 23, 3300. Doi: 10.1007/s11356-015-5534-z
  • Silici, S., Sagdic, O., Ekici, L., 2010. Total phenolic content, antiradical, antioxidant, and antimicrobial activities of rhododendron honeys. Food Chemistry, 121(1), 238–243. Doi: 10.1016/j.foodchem.2009.11.078
  • Silici, S., Sarioglu, K., Dogan, M., Karaman, K., 2014. HPLC-DAD Analysis to identify the phenolic profile of rhododendron honeys collected from different regions in Turkey. International Journal of Food Properties,17(5), 1126–1135. Doi: 10.1080/10942912.2012.698441
  • Tatli, O., Karaca, Y., Turkmen, S., Gulgen, G. S., Sahin, A., Eryigit, U., Fazli, O., Karaguzel, E., Mentese, A., Orem, A., Cansu, A., Turedi, S., Gunduz, A., 2016. The effect of mad honey on testosterone levels of male rats. Bratislavske Lekarske Listy, 117(11):677-680. Doi: 10.4149/BLL_2016_130.

Year 2017, Volume: 9 Issue: 2, 40 - 46, 01.12.2017

Hüseyin Şahin Zehra Can Sevgi Kolaylı

Abstract

References

  • Ahmed, S., Othman, N. H., 2013. Honey as a Potential Natural Anticancer Agent: A Review of Its Mechanisms. Evidence-Based Complementary and Alternative Medicine, 2013, 829070. Doi.org/10.1155/2013/829070
  • Allen K. L., Molan P. C., Reid G. M., 1991. A survey of the antibacterial activity of some New Zealand honeys. Journal of Pharmacy and Pharmacology, 43, 817–822.
  • Al-Waili N. S., 2004. Natural honey lowers plasma glucose, C-reactive protein, homocysteine, and blood lipids in healthy, diabetic, and hyperlipidemic subjects: comparison with dextrose and sucrose. Journal of Medicinal Food, 7,100-107. Doi: 10.1089/109662004322984789
  • Can, Z., Yildiz, O., Sahin, H., Akyuz Turumtay E., Silici S., Kolayli S., 2015. An investigation of Turkish honeys: Their pyhysico-chemical properties, antioxidant capacities and phenolic profiles. Food Chemistry, 180, 133-41. Doi: 10.1016/j.foodchem.2015.02.024
  • Jeddar A., Kharsany A., Ramsaroop U. G., Bhamjee A., Haffejee I. E., Moosa A., 1985. The antibacterial action of honey: an in vitro study. South African Medical Journal, 67, 257-258.
  • Kandil, A., El-Banby, M., Abdel-Wahed, G. K., Abdel-Gawwad, M., Fayez, M., 1987. Curative properties of true floral and false non-floral honeys on induced gastric ulcers. Journal of Drug Research, 17, 103-106.
  • Kurtoğlu, S., 1992. Zehirlenmeler, Teşhis ve Tedavi, Kayseri: Erciyes Ünviversitesi Yayınları, 30, 569-570.
  • Larson-Meyer, D. E., Willis, K. S., Willis, L. M., Austin, K. J., Hart, A. M., Breton, A. B., Alexander, B. M., 2010. Effect of honey versus sucrose on appetite, appetite-regulating hormones, and postmeal thermogenesis. Journal of the American College of Nutrition, 29, 5, 482-493.
  • Louveaux, J., Maurizio, A., Vorwohl, G., 1978. Methods of melissopalynology. Bee World, 59, 139–157.
  • Manuja, R., Sachdeva, S., Jain, A., Chaudhary, J., 2013. A comprehensive review on biological activities of p-hydroxy benzoic acid and its derivatives. International Journal of Pharmaceutical Sciences Review and Research, 20, 109-115.
  • Miniati E., 2007. Assessment of phenolic compounds in biological samples. Phenolics in Biological Samples, 43, 4, 362-368.
  • Oksana, S., Marian, B., Mahendra, R., Hong Bo, S., 2012. Plant phenolic compounds for food, pharmaceutical and cosmetiсs production. Journal of Medicinal Plants Research, 6, 2526-2539.
  • Pamir, F., 1969. Klinik Toksikoloji. Ankara: Ankara Yarı Açık Cezaevi Matbaası, 457-458.
  • Pasupuleti, V. R., Sammugam, L., Ramesh, N., Gan, S. H., 2017. Honey, Propolis, and Royal Jelly: A Comprehensive Review of Their Biological Actions and Health Benefits. Oxidative Medicine and Cellular Longevity, 2017, 1259510. Doi:10.1155/2017/1259510
  • Rani, G. N., Budumuru, R., Bandaru, N. R., 2017. Antimicrobial Activity of Honey with Special Reference to Methicillin Resistant Staphylococcus aureus (MRSA) and Methicillin Sensitive Staphylococcus aureus (MSSA). Journal of Clinical and Diagnostic Research, 11(8), DC05–DC08. Doi: 10.7860/JCDR/2017/30085.10347
  • Rasgele, P., Kekecoglu, M. 2014. Physico-chemical properties of rhododendron honey produced in Turkey. Herba Polonica, 59(3), 88-97. Doi:10.2478/hepo-2013-0019
  • Ruiz-Ruiz, J. C., Matus-Basto, A. J., Acereto-Escoffié, P., Segura-Campos M. R., 2017. Antioxidant and anti-inflammatory activities of phenolic compounds isolated from Melipona beecheii honey, Journal Food and Agricultural Immunology, 28(6), 1424-1437. Doi: 10.1080/09540105.2017.1347148
  • Sahin, H., 2014. Analysis of Grayanotoxin-III (GTX-III) Isoform in rhododendron honeys and its plants by LC-MS/MS, PhD. Thesis, Karadeniz Technical University, The Graduate School of Natural and Applied Sciences, Chemistry Graduate Program, Trabzon, Turkey.
  • Sahin, H., 2016. Honey as an apitherapic product: its inhibitory effect on urease and xanthine oxidase, Journal of Enzyme Inhibition and Medicinal Chemistry, 31:3, 490-494, Doi: 10.3109/14756366.2015.1039532
  • Sahin, H., Akyuz Turumtay, E., Yildiz, O., Kolayli, S., 2015. Grayanotoxin-III detection and antioxidant activity of mad honey. International Journal of Food Properties, 18(12), 2665-2674. Doi: 10.1080/10942912.2014.999866.
  • Silici, S., Doğan, Z., Sahin, H., Atayoglu, T., Yakan, B., 2016. Acute effects of grayanotoxin in rhododendron honey on kidney functions in rats. Environmental Science and Pollution Research, 23, 3300. Doi: 10.1007/s11356-015-5534-z
  • Silici, S., Sagdic, O., Ekici, L., 2010. Total phenolic content, antiradical, antioxidant, and antimicrobial activities of rhododendron honeys. Food Chemistry, 121(1), 238–243. Doi: 10.1016/j.foodchem.2009.11.078
  • Silici, S., Sarioglu, K., Dogan, M., Karaman, K., 2014. HPLC-DAD Analysis to identify the phenolic profile of rhododendron honeys collected from different regions in Turkey. International Journal of Food Properties,17(5), 1126–1135. Doi: 10.1080/10942912.2012.698441
  • Tatli, O., Karaca, Y., Turkmen, S., Gulgen, G. S., Sahin, A., Eryigit, U., Fazli, O., Karaguzel, E., Mentese, A., Orem, A., Cansu, A., Turedi, S., Gunduz, A., 2016. The effect of mad honey on testosterone levels of male rats. Bratislavske Lekarske Listy, 117(11):677-680. Doi: 10.4149/BLL_2016_130.
There are 24 citations in total.

Details

Subjects Food Engineering
Journal Section Makaleler
Authors

Hüseyin Şahin

Zehra Can This is me

Sevgi Kolaylı

Publication Date December 1, 2017
Published in Issue Year 2017 Volume: 9 Issue: 2

Cite

APA Şahin, H., Can, Z., & Kolaylı, S. (2017). Bazı Ormangülü Ballarının Fenolik İçerik Kompozisyonu. Arıcılık Araştırma Dergisi, 9(2), 40-46.
AMA Şahin H, Can Z, Kolaylı S. Bazı Ormangülü Ballarının Fenolik İçerik Kompozisyonu. Arıcılık Araştırma Dergisi. December 2017;9(2):40-46.
Chicago Şahin, Hüseyin, Zehra Can, and Sevgi Kolaylı. “Bazı Ormangülü Ballarının Fenolik İçerik Kompozisyonu”. Arıcılık Araştırma Dergisi 9, no. 2 (December 2017): 40-46.
EndNote Şahin H, Can Z, Kolaylı S (December 1, 2017) Bazı Ormangülü Ballarının Fenolik İçerik Kompozisyonu. Arıcılık Araştırma Dergisi 9 2 40–46.
IEEE H. Şahin, Z. Can, and S. Kolaylı, “Bazı Ormangülü Ballarının Fenolik İçerik Kompozisyonu”, Arıcılık Araştırma Dergisi, vol. 9, no. 2, pp. 40–46, 2017.
ISNAD Şahin, Hüseyin et al. “Bazı Ormangülü Ballarının Fenolik İçerik Kompozisyonu”. Arıcılık Araştırma Dergisi 9/2 (December 2017), 40-46.
JAMA Şahin H, Can Z, Kolaylı S. Bazı Ormangülü Ballarının Fenolik İçerik Kompozisyonu. Arıcılık Araştırma Dergisi. 2017;9:40–46.
MLA Şahin, Hüseyin et al. “Bazı Ormangülü Ballarının Fenolik İçerik Kompozisyonu”. Arıcılık Araştırma Dergisi, vol. 9, no. 2, 2017, pp. 40-46.
Vancouver Şahin H, Can Z, Kolaylı S. Bazı Ormangülü Ballarının Fenolik İçerik Kompozisyonu. Arıcılık Araştırma Dergisi. 2017;9(2):40-6.