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Colonic cancers fistulised to other segments of the digestive tube. Case series and review of literature.

Year 2016, Volume: 1 Issue: 1, 8 - 10, 28.12.2016
https://doi.org/10.25000/acem.289228

Abstract

Background

Occurrence of enteric fistulas caused by colon cancer is a rare. Preoperative diagnosis has some difficulty because of non-specific presentation and lack of appropriate combination of diagnostic techniques. 

Methods

From November 2008 to April 2012, patients with entero-enteric fistulas caused by colon cancer were reviewed with regard to demographic variables, clinical presentation, diagnostic evaluation, intra-operative findings, type of surgical procedure and pathologic examination.

Results

There were four (3.92%) fistulas caused by colon cancer among 102 patients with adenocarcinoma of the colon. Fistulas were one colo-duodenal, one colo-gastric, one ceco-sigmoidal and one sigmoido-rectal in patients with a mean age 56.5 years. Presence of fistulas was not diagnosed preoperatively in any of the patients by using standard diagnostic techniques, i.e., endoscopy and computed tomography. Complete resection of tumor with tract of fistula was performed in all patients. Mean duration of follow-up period was 12.25 months, liver metastasis was detected in one patient, entero-cutaneous fistula in one.

Conclusions

Malignant fistula formation caused by colon cancers is a rare event. Preoperative diagnosis could be achieved by using a combination of barium enema or meal and endoscopy. Surgical treatment via oncologic en bloc resection with negative microscopic margins is important for long-term survival.

References

  • 1. Takahashi M, Fukuda T. Ileorectal fistula due to a rectal cancer-A case report. Int J Surg Case Rep 2011; 2: 20-1.
  • 2. Aydin U, Yazici P, Ozütemiz O, Güler A. Outcomes in the management of gastrocolic fistulas: a single surgical unit's experience. Turk J Gastroenterol 2008; 19: 152-7.
  • 3. Soulsby R, Leung E, Williams N. Malignant colo-duodenal fistula; case report and review of the literature. World J Surg Oncol 2006; 4: 86.
  • 4. Halevy A, Bracha M, Jeroukhimov I, et al. En bloc resection for malignant colouterine fistula. Tech Coloproctol 2010; 14: 37-9.
  • 5. Sımsek Z, Altinbas A, Ekiz F, et al. Cancer of the transverse colon revealed by a gastrocolic fistula. Turk J Gastroenterol 2011; 22: 107-8.
  • 6. Kamath AS, Iqbal CW, Pham TH, et al. Management and outcomes of primary coloduodenal fistulas. J Gastrointest Surg 2011; 15: 1706-11.
  • 7. Hyun YS, Han DS, Kim TY, et al. Education and imaging. Gastrointestinal: Sigmoidocecal fistula diagnosed with colonoscopy. J Gastroenterol Hepatol 2011; 26:208.
  • 8. No authors listed. Clinicopathologic conference: well differentiated adenocarcinoma of the cecum with cecosigmoidal fecal fistula. Ill Med J 1952; 102: 274-9.
  • 9. Matsuo S, Eto T, Ohara O, et al. Gastrocolic fistula originating from transverse colon cancer: report of a case and review of the Japanese literature. Surg Today 1994; 24: 1085-9.
  • 10. Tavenor T, Smith S, Sullivan S. Gastrocolic fistula. A review of 15 cases and an update of the literature. J Clin Gastroenterol 1993; 16:189-91.

Diğer sindirim borusu bölümlerine fistül oluşturan Kolonik kanserler. Olgu serisi ve literatür derlemesi.

Year 2016, Volume: 1 Issue: 1, 8 - 10, 28.12.2016
https://doi.org/10.25000/acem.289228

Abstract

Giriş

Kolon kanserinin sebep olduğu enterik fistüller nadir görülür. Ameliyat öncesi tanı, spesifik olmayan sunum ve uygun tanı teknikleri kombinasyonu bulunmaması nedeniyle bir miktar zorluk çekmektedir.

Yöntemler

Kasım 2008 - Nisan 2012 arasında demografik değişkenler, klinik tablo, tanı değerlendirme, intraoperatif bulgular, cerrahi girişim tipi ve patolojik inceleme açısından entero-enterik fistüllü hastalar gözden geçirildi.

Bulgular

Kolon adenokarsinomalı 102 hasta içinde kolon kanserine bağlı dört fistül vardı (% 3.92). Yaş ortalaması 56.5 olan hastalarda bir kolo-duodenal, bir kolo-gastrik, bir ceco-sigmoidal ve bir sigmoid-rektal fistül görüldü. Fistüllerin varlığı, standart tanı teknikleri, yani endoskopi ve bilgisayarlı tomografi kullanılarak preoperatif olarak teşhis edilemedi. Bütün hastalarda tümör-fistül dokusu rezeksiyonu yapıldı. İzlem süresi ortalama 12.25 ay, bir hastada karaciğer metastazı, bir hastada entero-kutanöz fistül saptandı.

Sonuçlar

Kolon kanserlerinden kaynaklanan malign fistül oluşumu nadir görülen bir olaydır. Ameliyat öncesi tanı, baryum lavman veya yemek ve endoskopi kombinasyonu kullanılarak başarılabilir. Onkolojik en blok rezeksiyon ve negatif mikroskobik cerrahi sınır, uzun süreli sağkalım için önemlidir.

References

  • 1. Takahashi M, Fukuda T. Ileorectal fistula due to a rectal cancer-A case report. Int J Surg Case Rep 2011; 2: 20-1.
  • 2. Aydin U, Yazici P, Ozütemiz O, Güler A. Outcomes in the management of gastrocolic fistulas: a single surgical unit's experience. Turk J Gastroenterol 2008; 19: 152-7.
  • 3. Soulsby R, Leung E, Williams N. Malignant colo-duodenal fistula; case report and review of the literature. World J Surg Oncol 2006; 4: 86.
  • 4. Halevy A, Bracha M, Jeroukhimov I, et al. En bloc resection for malignant colouterine fistula. Tech Coloproctol 2010; 14: 37-9.
  • 5. Sımsek Z, Altinbas A, Ekiz F, et al. Cancer of the transverse colon revealed by a gastrocolic fistula. Turk J Gastroenterol 2011; 22: 107-8.
  • 6. Kamath AS, Iqbal CW, Pham TH, et al. Management and outcomes of primary coloduodenal fistulas. J Gastrointest Surg 2011; 15: 1706-11.
  • 7. Hyun YS, Han DS, Kim TY, et al. Education and imaging. Gastrointestinal: Sigmoidocecal fistula diagnosed with colonoscopy. J Gastroenterol Hepatol 2011; 26:208.
  • 8. No authors listed. Clinicopathologic conference: well differentiated adenocarcinoma of the cecum with cecosigmoidal fecal fistula. Ill Med J 1952; 102: 274-9.
  • 9. Matsuo S, Eto T, Ohara O, et al. Gastrocolic fistula originating from transverse colon cancer: report of a case and review of the Japanese literature. Surg Today 1994; 24: 1085-9.
  • 10. Tavenor T, Smith S, Sullivan S. Gastrocolic fistula. A review of 15 cases and an update of the literature. J Clin Gastroenterol 1993; 16:189-91.
There are 10 citations in total.

Details

Subjects Surgery
Journal Section Original Research
Authors

Ali Kılıç

Mustafa Hasbahçeci

Orhan Alimoğlu This is me

Fatih Başak

Abdullah Şişik

Tolga Canbak

Publication Date December 28, 2016
Published in Issue Year 2016 Volume: 1 Issue: 1

Cite

Vancouver Kılıç A, Hasbahçeci M, Alimoğlu O, Başak F, Şişik A, Canbak T. Colonic cancers fistulised to other segments of the digestive tube. Case series and review of literature. Arch Clin Exp Med. 2016;1(1):8-10.