Case Report
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Left atrial extension of metastatic renal cell carcinoma via pulmonary vein: A case report

Year 2018, Volume:3 Issue: 3, 204 - 206, 30.11.2018
https://doi.org/10.25000/acem.450495

Abstract

Cardiac involvement from renal cell carcinoma is rare but well-recognized
entity with several cases reported in literature. In majority of cases, the
tumor reaches the right heart cavities through a neoplastic thrombus within
inferior vena cava.  Other mechanisms are
dissemination via hematogeous spread and direct extension from either
mediastinal or lung lesions involving pulmonary veins. Left heart involvement
from renal cell carcinoma with normal inferior vena cava is extremely rare.
Direct extension of metastatic pulmonary mass to left atrium from renal cell
carcinoma via pulmonary veins is even rarer.



We report a case of left atrial extension via pulmonary vein from metastatic
renal cell carcinoma who presented with left cerebellar and right thalamic
acute ischemic lesions along with multiple metastatic lesions.

References

  • 1. Schreffler SM, Paolo WF, Kloss BT. Spontaneous showering of tumor emboli in a patient with advanced primary lung cancer: a case report. Int J Emerg Med. 2012;5:27.
  • 2. Lin M, Ku S, Wu M, Yu CJ. Intracardiac extension of lung cancer via the pulmonary vein. Thorax. 2008;63:1122.
  • 3. Funakoshi Y, Mukohara T, Kataoka T, Tomioka H, Chayahara N, Fujiwara Y, et al. Left atrial extension of metastatic lung tumor via pulmonary vein: report on the first case of Ewing sarcoma. Rare Tumors. 2010;2:53.
  • 4. Kojiro O, Yasuyoshi M, Kensuke M, Matsuo T, Mochizuki Y, Sakai H. Left atrial metastasis of renal cell carcinoma: a case report and review of the literature. BMC Res Notes. 2014; 7:520.
  • 5. Frederic C, Agathe S, Marc R, Kuntze T, Czesla M, Walther T, et al. Intracardiac renal cell carcinoma metastasis. Eur J Cardiothorac Surg. 2008;34:697-9.
  • 6. Fogel R, Balady G.J, Klein M.D, Rajaii-Khorasani A. Metastatic Renal Cell Carcinoma An Unusual Cause of Syncope. Chest. 1990;98:481-2.
  • 7. Aburto J, Bruckner BA, Blackmon SH, Beyer EA, Reardon MJ. Renal cell carcinoma, metastatic to the left ventricle. Tex Heart Inst J. 2009;36:48-9.
  • 8. Zhang B, Malouf J, Young P, Kohli M, Dronca R. Cardiac metastasis in renal cell carcinoma without vena cava or atrial involvement: an unusual presentation of metastatic disease. Rare Tumors. 2013;5:29.
  • 9. Atik FA, Navia JL, Krishnamurthi V, Singh G, Shiota T, Pitas G, et al. Solitary massive right ventricular metastasis of renal cell carcinoma without inferior vena cava or right atrium involvement. J Card Surg. 2006;21:304-6.
  • 10. Hunsaker RP, Stone JR. Images in clinical medicine. Renal cell carcinoma extending into the vena cava and side of the heart. New Eng J Med. 2001;345:1676.
  • 11. Motwani M, Kidambi A, Herzog BA, Uddin A, Greenwood JP, Plein S. MR imaging of cardiac tumors and masses: a review of methods and clinical applications. Radiology. 2013;268:26-43.
  • 12. Hoffmann U, Globits S, Schima W, Loewe C, Puig S, Oberhuber G, et al. Usefulness of magnetic resonance imaging of cardiac and paracardiac masses. Am J Cardiol. 2003;92:890-5.
  • 13. Fussen S, De Boeck BW, Zellweger MJ, Bremerich J, Goetschalckx K, Zuber M, et al. Cardiovascular magnetic resonance imaging for diagnosis and clinical management of suspected cardiac masses and tumours. Eur Heart J. 2011;32:1551-60.

Metastatik renal hücreli karsinomun pulmoner ven yoluyla sol atriyuma uzanımı: Bir olgu sunumu

Year 2018, Volume:3 Issue: 3, 204 - 206, 30.11.2018
https://doi.org/10.25000/acem.450495

Abstract



Renal hücreli karsinomun kardiyak tutulumu nadir ancak iyi bilinen bir
olgudur ve literatürde bir çok vaka bildirilmiştir. Tümör çoğu durumda, sağ
kalp boşluklarına vena kava inferiyor
içinde neoplastik trombüs yoluyla ulaşır.  Bu mekanizma dışında, kardiyak tutulum,
hematojen yolla olabileceği gibi, mediyastinal veya akciğer lezyonlarının pulmoner
venler yoluyla direk yayılımı ile de ortaya çıkabilir. Ancak vena kava inferiyor
tutulumu olmaksızın tümörün sol kalbe ulaşması son derece nadirdir.  Renal hücreli karsinomun akciğer metastazlarının,
p
ulmoner venler yoluyla sol atriyuma direk
uzanımı daha da nadirdir.



Bu makalede, çok sayıda
metastatik lezyonu olan ve sol serebellar ve sağ talamik akut iskemik
lezyonlara bağlı belirtileri ortaya çıkan, 
pulmoner ven yoluyla sol atriyuma direk uzanımı olan metastatik renal
hücreli karsinom olgusunu sunuyoruz.

References

  • 1. Schreffler SM, Paolo WF, Kloss BT. Spontaneous showering of tumor emboli in a patient with advanced primary lung cancer: a case report. Int J Emerg Med. 2012;5:27.
  • 2. Lin M, Ku S, Wu M, Yu CJ. Intracardiac extension of lung cancer via the pulmonary vein. Thorax. 2008;63:1122.
  • 3. Funakoshi Y, Mukohara T, Kataoka T, Tomioka H, Chayahara N, Fujiwara Y, et al. Left atrial extension of metastatic lung tumor via pulmonary vein: report on the first case of Ewing sarcoma. Rare Tumors. 2010;2:53.
  • 4. Kojiro O, Yasuyoshi M, Kensuke M, Matsuo T, Mochizuki Y, Sakai H. Left atrial metastasis of renal cell carcinoma: a case report and review of the literature. BMC Res Notes. 2014; 7:520.
  • 5. Frederic C, Agathe S, Marc R, Kuntze T, Czesla M, Walther T, et al. Intracardiac renal cell carcinoma metastasis. Eur J Cardiothorac Surg. 2008;34:697-9.
  • 6. Fogel R, Balady G.J, Klein M.D, Rajaii-Khorasani A. Metastatic Renal Cell Carcinoma An Unusual Cause of Syncope. Chest. 1990;98:481-2.
  • 7. Aburto J, Bruckner BA, Blackmon SH, Beyer EA, Reardon MJ. Renal cell carcinoma, metastatic to the left ventricle. Tex Heart Inst J. 2009;36:48-9.
  • 8. Zhang B, Malouf J, Young P, Kohli M, Dronca R. Cardiac metastasis in renal cell carcinoma without vena cava or atrial involvement: an unusual presentation of metastatic disease. Rare Tumors. 2013;5:29.
  • 9. Atik FA, Navia JL, Krishnamurthi V, Singh G, Shiota T, Pitas G, et al. Solitary massive right ventricular metastasis of renal cell carcinoma without inferior vena cava or right atrium involvement. J Card Surg. 2006;21:304-6.
  • 10. Hunsaker RP, Stone JR. Images in clinical medicine. Renal cell carcinoma extending into the vena cava and side of the heart. New Eng J Med. 2001;345:1676.
  • 11. Motwani M, Kidambi A, Herzog BA, Uddin A, Greenwood JP, Plein S. MR imaging of cardiac tumors and masses: a review of methods and clinical applications. Radiology. 2013;268:26-43.
  • 12. Hoffmann U, Globits S, Schima W, Loewe C, Puig S, Oberhuber G, et al. Usefulness of magnetic resonance imaging of cardiac and paracardiac masses. Am J Cardiol. 2003;92:890-5.
  • 13. Fussen S, De Boeck BW, Zellweger MJ, Bremerich J, Goetschalckx K, Zuber M, et al. Cardiovascular magnetic resonance imaging for diagnosis and clinical management of suspected cardiac masses and tumours. Eur Heart J. 2011;32:1551-60.
There are 13 citations in total.

Details

Primary Language English
Subjects ​Internal Diseases
Journal Section Case Report
Authors

Mehmet Şeker 0000-0002-6745-0159

Cengiz Erol 0000-0003-3468-7712

Publication Date November 30, 2018
Published in Issue Year 2018 Volume:3 Issue: 3

Cite

Vancouver Şeker M, Erol C. Left atrial extension of metastatic renal cell carcinoma via pulmonary vein: A case report. Arch Clin Exp Med. 2018;3(3):204-6.