İntragastrik Balon ve Botulinum Toksin Enjeksiyonunun Kilo Kaybı Üzerine Kısa Dönem Etkilerinin Karşılaştırılması

Year 2022, Volume: 7 Issue: 3, 51 - 55, 26.12.2022

Muzaffer Al

https://doi.org/10.25000/acem.1168617

Abstract

Amaç: Morbid obez olmayan hastalarda endoskopik intragastrik balon (IGB) yerleştirme ve intragastrik botulinum toksin-A (BTX-A) enjeksiyonunun kilo kaybı açısından etkilerini karşılaştırmak.
Yöntemler: Bu retrospektif tek merkezli çalışma 01.08.2020 ile 01.01.2022 tarihleri arasında gerçekleştirildi. Beden kitle indeksi (BKİ) <40 olan ve komorbiditesi olmayan toplam 39 hasta çalışmaya dahil edildi. Olguların 19'una intragastrik BTX-A enjeksiyonu ve 20'sine IGB yerleştirmesi yapıldı. Hastalar işlemlerden 1 ay ve 6 ay sonra değerlendirildi.
Bulgular: Ortalama yaş BTX-A grubunda 39.4 ± 8.6 ve IGB grubunda 37.3 ± 10.4 idi (p = 0.496). BTX-A grubunun %78,9'u ve IGB grubunun %75,0'ı kadındı (p = 1.000). Her iki grupta da işlem öncesi ile karşılaştırıldığında işlemden 1 ay sonra ve işlemden 1 ay sonrası ile karşılaştırıldığında işlemden 6 ay sonra ortanca ağırlık anlamlı düzeyde azaldı (her iki grup için p<0,001). BTX-A grubu ile karşılaştırıldığında hem 1. hem de 6. ayda medyan kilo kaybı IGB grubunda anlamlı düzeyde daha fazlaydı (her ikisi için p < 0,001).
Sonuç: Çalışmamızda müdahale sonrası 1. ve 6. ayda kilo kaybı ile ölçüldüğü üzere, IGB yerleştirilmesi intragastrik BTX-A enjeksiyonundan daha başarılı bir endoskopik bariatrik prosedür gibi görünmektedir. Obezite ile ilişkili komorbiditesi olmayan BKİ 40'ın altında olan hastalarda IGB tercih edilebilir.

Keywords

Obezite, endoskopik bariatrik prosedürler, intragastrik balon yerleştirme, intragastrik botulinum toksin-A enjeksiyonu, kilo kaybı

Comparison of The Short-Term Effects of Intragastric Balloon and Botulinum Toxin Injection On Weight Loss

Abstract

Aim: To compare the effects of endoscopic intragastric balloon (IGB) placement and intragastric botulinum toxin-A (BTX-A) injection in terms of weight loss among patients with non-morbid obesity.
Methods: This retrospective single center study was conducted between 01.08.2020 and 01.01.2022. A total of 39 patients with a body mass index (BMI) of <40 without comorbidities were included in the study. Nineteen underwent intragastric BTX-A injection and 20 underwent IGB placement. Patients were evaluated 1 month and 6 months after the procedures.
Results: Mean age was 39.4 ± 8.6 in the BTX-A group and 37.3 ± 10.4 in the IGB group (p = 0.496). 78.9% of the BTX-A group and 75.0% of the IGB group were female (p = 1.000). In both groups, the median weight 1 month after the procedure was significantly lower than before the procedure, and the median weight 6 months after the procedure was significantly lower than 1 month after the procedure (p<0.001 for both groups). The median weight loss in the IGB group at both the 1st and 6th months was significantly greater than the corresponding values of the BTX-A group (p < 0.001 for both).
Conclusion: IGB insertion appears to be a more successful endoscopic bariatric procedure than intragastric BTX-A injection, as measured by weight loss at post-intervention 1 month and 6 months. IGB may be preferred in patients with a BMI below 40 without obesity-related comorbidity.

Keywords

Obesity, endoscopic bariatric procedures, intragastric balloon placement, intragastric botulinum toxin-A injection, weight loss

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