Case Report
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Bariatrik cerrahi sonrası gelişen papil ödeminin eşlik ettiği Wernicke ensefalopatisi: bir olgu sunumu

Year 2021, Volume: 54 Issue: 3, 497 - 500, 01.01.2022
https://doi.org/10.20492/aeahtd.932741

Abstract

Wernicke ensefalopatisi konfüzyon, oftalmopleji ve ataksi üçlüsü ile karakterize bir akut ensefalopati tablosudur. Etiyolojide tiaminin yetersiz alımı veya emilim bozukluğu ile ilişkili olabilecek birçok neden bildirilmiştir. Burada, erken muayenede papil ödemi ve obezite dışında bir özellik olmadığı için tanısı geciken, gastrik bypass ameliyatı sonrası gelişmiş bir Wernicke ensefalopatisi olgusunu sunuyoruz. Takip sırasında hastada oftalmopleji ve tetraparezi gelişti ve tabloya bilinç değişikliği de eklendi. Ayırıcı tanıda Wernicke ensefalopatisi düşünülür düşünülmez yüksek doz intravenöz tiamin tedavisi başlandı ve hastanın kliniği progresif olarak düzeldi. Bu vakada papil ödemi, obezite ve tablonun karakteristik bulgularının başlangıçta silik olması tanıda gecikmeye yol açmıştır. Bu vakanın Wernicke ensefalopatisinin sık karşılaşılmayan bulguları hakkında farkındalığı artıracağı için önemli olduğu düşünülmüştür.

References

  • 1. Latt N, Dore G. Thiamine in the treatment of Wernicke encephalopathy in patients with alcohol use disorders. Intern Med J. 2014;44: 911-915. doi: 10.1111/imj.12522. PMID: 25201422.
  • 2. Ferrier DR. Vitamins. In: Harvey RA; ed. Lippincott’s Illustrated Reviews Biochemistry. Sixth Edition. Philadelphia: Lippincott Williams & Wilkins; 2013. p.858
  • 3. Saeki K, Saito Y, Komaki H, et al. Thiamine-deficient encephalopathy due to excessive intake of isotonic drink or overstrict diet therapy in Japanese children. Brain Dev. 2010;32: 556-563. doi: 10.1016/j.braindev.2009.08.004. Epub 2009 Sep 26. PMID: 19783110.
  • 4. Aasheim ET. Wernicke encephalopathy after bariatric surgery: a systematic review. Ann Surg. 2008;248: 714-720. doi: 10.1097/SLA.0b013e3181884308. PMID: 18948797.
  • 5. Isen DR, Kline LB. Neuro-ophthalmic Manifestations of Wernicke Encephalopathy. Eye Brain. 2020; 12: 49-60. doi: 10.2147/EB.S234078. PMID: 32636690; PMCID: PMC7335288.
  • 6. Bohnsack BL, Patel SS. Peripapillary nerve fiber layer thickening, telangiectasia, and retinal hemorrhages in wernicke encephalopathy. J Neuroophthalmol. 2010;30: 54-58. doi: 10.1097/WNO.0b013e3181ceb4d0. PMID: 20182209.
  • 7. DiNicolantonio JJ, Niazi AK, Lavie CJ, et al. Thiamine supplementation for the treatment of heart failure: a review of the literature. Congest Heart Fail. 2013; 19: 214-222. doi: 10.1111/chf.12037. PMID: 23910704.
  • 8. Zuccoli G, Pipitone N. Neuroimaging findings in acute Wernicke's encephalopathy: review of the literature. AJR Am J Roentgenol. 2009; 192:501-508. doi: 10.2214/AJR.07.3959. PMID: 19155417.
  • 9. Ashraf VV, Prijesh J, Praveenkumar R, et al. Wernicke's encephalopathy due to hyperemesis gravidarum: Clinical and magnetic resonance imaging characteristics. J Postgrad Med. 2016; 62: 260-263. doi: 10.4103/0022-3859.191005. PMID: 27763485; PMCID: PMC5105213.
  • 10. McEntee WJ. Wernicke's encephalopathy: an excitotoxicity hypothesis. Metab Brain Dis. 1997;12: 183-192. PMID: 9346467.
  • 11. Nishimoto A, Usery J, Winton JC, et al. High-dose Parenteral Thiamine in Treatment of Wernicke's Encephalopathy: Case Series and Review of the Literature. In Vivo. 2017; 31: 121-124. doi: 10.21873/invivo.11034. PMID: 28064230; PMCID: PMC5354137.

Wernicke Encephalopathy with papilledema after bariatric surgery: a case report

Year 2021, Volume: 54 Issue: 3, 497 - 500, 01.01.2022
https://doi.org/10.20492/aeahtd.932741

Abstract

Wernicke encephalopathy is an acute encephalopathy, characterized by the triad of mental confusion, ophthalmoplegia, and gait ataxia. Many reasons have been reported in the etiology that may be related to insufficient intake or malabsorption of thiamine. Here, we present a case of Wernicke's encephalopathy that developed after gastric bypass surgery, whose diagnosis was delayed because there was no feature other than papillary edema and obesity at early examination. During follow-up, the patient developed ophthalmoplegia and tetraparesis, and a change in consciousness was added. When Wernicke's encephalopathy was considered in the diagnosis, her clinic improved progressively under high dose intravenous thiamine treatment. The fact that this case had papillary edema, being obese, and the characteristic findings of the picture were obscure at the beginning caused a delay in diagnosis. This case was thought to be important as it would increase awareness of the uncommon findings of Wernicke's encephalopathy.

References

  • 1. Latt N, Dore G. Thiamine in the treatment of Wernicke encephalopathy in patients with alcohol use disorders. Intern Med J. 2014;44: 911-915. doi: 10.1111/imj.12522. PMID: 25201422.
  • 2. Ferrier DR. Vitamins. In: Harvey RA; ed. Lippincott’s Illustrated Reviews Biochemistry. Sixth Edition. Philadelphia: Lippincott Williams & Wilkins; 2013. p.858
  • 3. Saeki K, Saito Y, Komaki H, et al. Thiamine-deficient encephalopathy due to excessive intake of isotonic drink or overstrict diet therapy in Japanese children. Brain Dev. 2010;32: 556-563. doi: 10.1016/j.braindev.2009.08.004. Epub 2009 Sep 26. PMID: 19783110.
  • 4. Aasheim ET. Wernicke encephalopathy after bariatric surgery: a systematic review. Ann Surg. 2008;248: 714-720. doi: 10.1097/SLA.0b013e3181884308. PMID: 18948797.
  • 5. Isen DR, Kline LB. Neuro-ophthalmic Manifestations of Wernicke Encephalopathy. Eye Brain. 2020; 12: 49-60. doi: 10.2147/EB.S234078. PMID: 32636690; PMCID: PMC7335288.
  • 6. Bohnsack BL, Patel SS. Peripapillary nerve fiber layer thickening, telangiectasia, and retinal hemorrhages in wernicke encephalopathy. J Neuroophthalmol. 2010;30: 54-58. doi: 10.1097/WNO.0b013e3181ceb4d0. PMID: 20182209.
  • 7. DiNicolantonio JJ, Niazi AK, Lavie CJ, et al. Thiamine supplementation for the treatment of heart failure: a review of the literature. Congest Heart Fail. 2013; 19: 214-222. doi: 10.1111/chf.12037. PMID: 23910704.
  • 8. Zuccoli G, Pipitone N. Neuroimaging findings in acute Wernicke's encephalopathy: review of the literature. AJR Am J Roentgenol. 2009; 192:501-508. doi: 10.2214/AJR.07.3959. PMID: 19155417.
  • 9. Ashraf VV, Prijesh J, Praveenkumar R, et al. Wernicke's encephalopathy due to hyperemesis gravidarum: Clinical and magnetic resonance imaging characteristics. J Postgrad Med. 2016; 62: 260-263. doi: 10.4103/0022-3859.191005. PMID: 27763485; PMCID: PMC5105213.
  • 10. McEntee WJ. Wernicke's encephalopathy: an excitotoxicity hypothesis. Metab Brain Dis. 1997;12: 183-192. PMID: 9346467.
  • 11. Nishimoto A, Usery J, Winton JC, et al. High-dose Parenteral Thiamine in Treatment of Wernicke's Encephalopathy: Case Series and Review of the Literature. In Vivo. 2017; 31: 121-124. doi: 10.21873/invivo.11034. PMID: 28064230; PMCID: PMC5354137.
There are 11 citations in total.

Details

Primary Language English
Subjects Clinical Sciences
Journal Section Case report
Authors

Zeynep Zıroglu 0000-0002-2859-5072

Tehran Allahverdiyev 0000-0003-4456-1849

Zerin Özaydın Aksun 0000-0003-1154-4276

Nursel Aydın 0000-0003-1502-370X

Publication Date January 1, 2022
Submission Date May 4, 2021
Published in Issue Year 2021 Volume: 54 Issue: 3

Cite

AMA Zıroglu Z, Allahverdiyev T, Özaydın Aksun Z, Aydın N. Wernicke Encephalopathy with papilledema after bariatric surgery: a case report. Ankara Eğitim ve Araştırma Hastanesi Tıp Dergisi. January 2022;54(3):497-500. doi:10.20492/aeahtd.932741