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            <front>

                <journal-meta>
                                                                <journal-id>ahi evran med j</journal-id>
            <journal-title-group>
                                                                                    <journal-title>Ahi Evran Medical Journal</journal-title>
            </journal-title-group>
                                        <issn pub-type="epub">2619-9203</issn>
                                                                                            <publisher>
                    <publisher-name>Kirsehir Ahi Evran University</publisher-name>
                </publisher>
                    </journal-meta>
                <article-meta>
                                        <article-id pub-id-type="doi">10.46332/aemj.1756023</article-id>
                                                                <article-categories>
                                            <subj-group  xml:lang="en">
                                                            <subject>Chest Diseases</subject>
                                                    </subj-group>
                                            <subj-group  xml:lang="tr">
                                                            <subject>Göğüs Hastalıkları</subject>
                                                    </subj-group>
                                    </article-categories>
                                                                                                                                                        <title-group>
                                                                                                                        <trans-title-group xml:lang="tr">
                                    <trans-title>GOLD 2025: KOAH Yönetiminde Güncel Bilimsel Yaklaşımlar</trans-title>
                                </trans-title-group>
                                                                                                                                                                                                <article-title>GOLD 2025: Current Scientific Approaches in COPD Management</article-title>
                                                                                                    </title-group>
            
                                                    <contrib-group content-type="authors">
                                                                        <contrib contrib-type="author">
                                                                    <contrib-id contrib-id-type="orcid">
                                        https://orcid.org/0000-0001-6437-1730</contrib-id>
                                                                <name>
                                    <surname>Bilgin</surname>
                                    <given-names>Mehmet Hakan</given-names>
                                </name>
                                                                    <aff>VAN YÜZÜNCÜ YIL ÜNİVERSİTESİ, TIP FAKÜLTESİ</aff>
                                                            </contrib>
                                                                                </contrib-group>
                        
                                        <pub-date pub-type="pub" iso-8601-date="20260429">
                    <day>04</day>
                    <month>29</month>
                    <year>2026</year>
                </pub-date>
                                        <volume>10</volume>
                                        <issue>1</issue>
                                        <fpage>4</fpage>
                                        <lpage>6</lpage>
                        
                        <history>
                                    <date date-type="received" iso-8601-date="20250801">
                        <day>08</day>
                        <month>01</month>
                        <year>2025</year>
                    </date>
                                                    <date date-type="accepted" iso-8601-date="20250925">
                        <day>09</day>
                        <month>25</month>
                        <year>2025</year>
                    </date>
                            </history>
                                        <permissions>
                    <copyright-statement>Copyright © 2017, Ahi Evran Medical Journal</copyright-statement>
                    <copyright-year>2017</copyright-year>
                    <copyright-holder>Ahi Evran Medical Journal</copyright-holder>
                </permissions>
            
                                                                                                <trans-abstract xml:lang="tr">
                            <p>GOLD 2025 kılavuzu, Kronik Obstrüktif Akciğer Hastalığı (KOAH) yönetiminde güncel bilimsel kanıtlara dayanan temel bir kaynak olarak geliştirilmiştir. Bu kılavuz, KOAH patogenezi, tanı yöntemleri, bireyselleştirilmiş tedavi stratejileri, yeni bronkodilatör ilaçlar, aşılama programları ve pulmoner rehabilitasyon gibi konuları kapsamlı bir şekilde ele almıştır. Sigara dumanı, biyokütle dumanı ve hava kirliliği gibi çevresel faktörlerin yanı sıra genetik yatkınlıkların KOAH gelişimindeki rolü vurgulanmıştır. Spirometri, biyobelirteçler ve görüntüleme teknikleri gibi tanı araçlarının önemi artırılmış, bireyselleştirilmiş ve multidisipliner tedavi yaklaşımlarının gerekliliği ön plana çıkarılmıştır. Yeni bronkodilatörler, aşılama stratejileri ve pulmoner rehabilitasyon programları hasta sonuçlarını iyileştirmek ve sağlık sistemi yükünü azaltmak amacıyla önerilmiştir. GOLD 2025, KOAH bakımında standartları yükselterek klinisyenlere, sağlık politikası yapıcılarına ve araştırmacılara yol göstermektedir.</p></trans-abstract>
                                                                                                                                    <abstract><p>The GOLD 2025 guideline was developed as an essential reference for managing Chronic Obstructive Pulmonary Disease (COPD) based on current scientific evidence. It comprehensively addressed COPD pathogenesis, diagnosis, personalized treatment strategies, novel bronchodilator therapies, vaccination programs, and pulmonary rehabilitation. The role of environmental factors, including cigarette smoke, biomass smoke, and air pollution, as well as genetic predisposition, was emphasized in COPD development. Diagnostic tools such as spirometry, biomarkers, and imaging techniques were highlighted, along with the importance of individualized and multidisciplinary treatment approaches. New bronchodilators, vaccination strategies, and pulmonary rehabilitation programs were designed to improve patient outcomes and reduce healthcare burden. GOLD 2025 set higher standards in COPD care, offering guidance to clinicians, healthcare policymakers, and researchers.</p></abstract>
                                                            
            
                                                                                        <kwd-group>
                                                    <kwd>bronchodilator agents</kwd>
                                                    <kwd>  COPD</kwd>
                                                    <kwd>  inhalation therapy</kwd>
                                                    <kwd>  vaccination</kwd>
                                            </kwd-group>
                            
                                                <kwd-group xml:lang="tr">
                                                    <kwd>aşılama</kwd>
                                                    <kwd>  bronkodilatör ajanlar</kwd>
                                                    <kwd>  inhalasyon tedavisi</kwd>
                                                    <kwd>  KOAH</kwd>
                                            </kwd-group>
                                                                                                                                        </article-meta>
    </front>
    <back>
                            <ref-list>
                                    <ref id="ref1">
                        <label>1</label>
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                    </back>
    </article>
