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Status of Reaching LDL Goals In Diabetic Patıents And Frequency Of Statin Treatment Compliance

Year 2012, Volume: 12 Issue: 3, 122 - 123, 01.03.2012

Abstract

Aim: Our aim was to evaluate the frequency of patients

with diabetes mellitus which reached the LDL cholesterol

goals and their competence with the statin treatment.

Method: LDL cholesterol levels were evaluated and reasons which effect the reaching the LDL goals were asked.

Results: 106 diabetic patients were included to the study.

Only %28.3 of such patients were at the LDL goal. Most

of these patients were not compatible with their statin

treatment and were effected with the statin arguments

in media.

Discussion: Statin treatment is important for the cardiovascular treatment. So that patients must be questioned

about their compliance to their treatment.

References

  • 1. American Diabetes Association. Et al. Standards of medical care in diabetes--2012. Diabetes Care. 2012 Jan;35 Suppl 1:S11-63.
  • 2. Türk Endokrinoloji ve Metabolizma Derneği Diabetes Mellitus ve Komplikasyonlarının Tanı, Tedavi ve İzlem Klavuzu 2011- http://www. turkendokrin.org/files/pdf/diabetes_klvz2011_web.pdf (05.08.12)
  • 3. Sattar N, Preiss D. Statins and risk of incident diabetes: a collaborative meta-analysis of randomised statin trials. Lancet. 2010 Feb 27;375(9716):735-742.
  • 4. Liao JK, Is Statin Discontinuation an Option in Patients Who Have Had a Stroke? Nat Clin Pract Neurol. 2008;4(1):18-19.
  • 5. Blanco M, Nombela F. Statin treatment withdrawal in ischemic stroke: a controlled randomized study. Neurology. 2007; Aug 28;69(9):904-910.
  • 6. Luigi X. Cubeddu. Statin Withdrawal: Clinical Implications and Molecular Mechanisms. Pharmacotherapy. 2006;26(9):1288-1296.
  • 7. C-Reactive Protein, Statins and the Risk of Vascular Events: A Better Understanding Behnood Bikdeli B.Cardiovascular Drugs and Therapy DOI: 10.1007/s10557-011-6323-7
  • 8. Sever PS, Dahlöf B Prevention of coronary and stroke events with atorvastatin in hypertensive patients who have average or lower-than-average cholesterol concentrations, in the AngloScandinavian Cardiac Outcomes Trial—Lipid Lowering Arm (ASCOT-LLA): a multicentre randomised controlled trial. Lancet 2003;361:1149-1158.
  • 9. Gurm HS, Hoogwerf B. The Heart Protection Study: High-risk patients benefit from statins regardless of LDL-C level. Clevaland Clinical Journal of Medicine. 2003;70(11): 991-997
  • 10.Bilge U. Statinlere Farklı Yaklaşımlar. Turkish Family Physician 2012 Vol:2 (3);1-5

Diyabetes Mellitus Hastalarında Hedef LDL Kolesterol Düzeylerine Ulaşma Durumu ve Statin Tedavisine Uyum Sıklığı

Year 2012, Volume: 12 Issue: 3, 122 - 123, 01.03.2012

Abstract

Amaç: 

Diyabetes Mellitus (DM) hastalarında hedef LDL kolesterol düzeylerine ulaşma oranı ve statin tedavisine uyum ile ilişkisini araştırmak.

Metod:

Çalışmaya katılan hastaların LDL kolesterol düzeylerine bakıldı ve hedef değerlere ulaşamama nedenleri sorgulandı.

Sonuçlar:

Çalışmaya 106 DM hastası dahil edildi. Hastaların %28,3’ü hedef LDL değerlerine sahipti. Hastaların büyük bir çoğunluğu statin tedavisine uyumsuzdu ve medyadaki statin tartışmalarından da etkilenmişti.

Tartışma: 

Statinlerin kardiyovasküler korumada önemlidir. Bu yüzden bu hastaların tedaviye uyumları açısından da değerlendirilmesi gereklidir.

References

  • 1. American Diabetes Association. Et al. Standards of medical care in diabetes--2012. Diabetes Care. 2012 Jan;35 Suppl 1:S11-63.
  • 2. Türk Endokrinoloji ve Metabolizma Derneği Diabetes Mellitus ve Komplikasyonlarının Tanı, Tedavi ve İzlem Klavuzu 2011- http://www. turkendokrin.org/files/pdf/diabetes_klvz2011_web.pdf (05.08.12)
  • 3. Sattar N, Preiss D. Statins and risk of incident diabetes: a collaborative meta-analysis of randomised statin trials. Lancet. 2010 Feb 27;375(9716):735-742.
  • 4. Liao JK, Is Statin Discontinuation an Option in Patients Who Have Had a Stroke? Nat Clin Pract Neurol. 2008;4(1):18-19.
  • 5. Blanco M, Nombela F. Statin treatment withdrawal in ischemic stroke: a controlled randomized study. Neurology. 2007; Aug 28;69(9):904-910.
  • 6. Luigi X. Cubeddu. Statin Withdrawal: Clinical Implications and Molecular Mechanisms. Pharmacotherapy. 2006;26(9):1288-1296.
  • 7. C-Reactive Protein, Statins and the Risk of Vascular Events: A Better Understanding Behnood Bikdeli B.Cardiovascular Drugs and Therapy DOI: 10.1007/s10557-011-6323-7
  • 8. Sever PS, Dahlöf B Prevention of coronary and stroke events with atorvastatin in hypertensive patients who have average or lower-than-average cholesterol concentrations, in the AngloScandinavian Cardiac Outcomes Trial—Lipid Lowering Arm (ASCOT-LLA): a multicentre randomised controlled trial. Lancet 2003;361:1149-1158.
  • 9. Gurm HS, Hoogwerf B. The Heart Protection Study: High-risk patients benefit from statins regardless of LDL-C level. Clevaland Clinical Journal of Medicine. 2003;70(11): 991-997
  • 10.Bilge U. Statinlere Farklı Yaklaşımlar. Turkish Family Physician 2012 Vol:2 (3);1-5
There are 10 citations in total.

Details

Primary Language Turkish
Journal Section Research Articles
Authors

Ahmet Keskin This is me

Publication Date March 1, 2012
Published in Issue Year 2012 Volume: 12 Issue: 3

Cite

APA Keskin, A. (2012). Diyabetes Mellitus Hastalarında Hedef LDL Kolesterol Düzeylerine Ulaşma Durumu ve Statin Tedavisine Uyum Sıklığı. Ankara Medical Journal, 12(3), 122-123.
AMA Keskin A. Diyabetes Mellitus Hastalarında Hedef LDL Kolesterol Düzeylerine Ulaşma Durumu ve Statin Tedavisine Uyum Sıklığı. Ankara Med J. March 2012;12(3):122-123.
Chicago Keskin, Ahmet. “Diyabetes Mellitus Hastalarında Hedef LDL Kolesterol Düzeylerine Ulaşma Durumu Ve Statin Tedavisine Uyum Sıklığı”. Ankara Medical Journal 12, no. 3 (March 2012): 122-23.
EndNote Keskin A (March 1, 2012) Diyabetes Mellitus Hastalarında Hedef LDL Kolesterol Düzeylerine Ulaşma Durumu ve Statin Tedavisine Uyum Sıklığı. Ankara Medical Journal 12 3 122–123.
IEEE A. Keskin, “Diyabetes Mellitus Hastalarında Hedef LDL Kolesterol Düzeylerine Ulaşma Durumu ve Statin Tedavisine Uyum Sıklığı”, Ankara Med J, vol. 12, no. 3, pp. 122–123, 2012.
ISNAD Keskin, Ahmet. “Diyabetes Mellitus Hastalarında Hedef LDL Kolesterol Düzeylerine Ulaşma Durumu Ve Statin Tedavisine Uyum Sıklığı”. Ankara Medical Journal 12/3 (March 2012), 122-123.
JAMA Keskin A. Diyabetes Mellitus Hastalarında Hedef LDL Kolesterol Düzeylerine Ulaşma Durumu ve Statin Tedavisine Uyum Sıklığı. Ankara Med J. 2012;12:122–123.
MLA Keskin, Ahmet. “Diyabetes Mellitus Hastalarında Hedef LDL Kolesterol Düzeylerine Ulaşma Durumu Ve Statin Tedavisine Uyum Sıklığı”. Ankara Medical Journal, vol. 12, no. 3, 2012, pp. 122-3.
Vancouver Keskin A. Diyabetes Mellitus Hastalarında Hedef LDL Kolesterol Düzeylerine Ulaşma Durumu ve Statin Tedavisine Uyum Sıklığı. Ankara Med J. 2012;12(3):122-3.