Adnan Menderes Üniversitesi Sağlık Bilimleri Fakültesi Dergisi

2587-2427

Aydin Adnan Menderes University

10.46237/amusbfd.1033604

Health Care Administration

Sağlık Kurumları Yönetimi

Vitamins and Non Alcoholic Fatty Liver Disease

Vitaminler ve Non Alkolik Yağlı Karaciğer Hastalığı

https://orcid.org/0000-0002-6526-9102

Kılınç

Aziz

Cihanbeyli Devlet Hastanesi

https://orcid.org/0000-0002-2213-4419

Akdevelioğlu

Yasemin

GAZİ ÜNİVERSİTESİ, SAĞLIK BİLİMLERİ FAKÜLTESİ, BESLENME VE DİYETETİK BÖLÜMÜ, BESLENME BİLİMLERİ ANABİLİM DALI

05 31 2022

6 2 383 393 12 07 2021 03 22 2022

2017

Adnan Menderes Üniversitesi Sağlık Bilimleri Fakültesi Dergisi

In parallel with the increasing obesity prevalence, non-alcoholic fatty liver disease has become the most common liver disease in many countries. Non-alcoholic fatty liver disease is an important cause of morbidity and mortality worldwide, as it has become the leading cause of liver transplantation, as well as cardiovascular, hepatic, metabolic and oncological sequelae. This epidemic and its consequences have prompted experts from around the world to identify effective strategies for the management and treatment of the disease. There is currently no approved drug therapy for the treatment of non-alcoholic fatty liver disease. Therefore, modifiable risk factors such as diet and exercise remain as cornerstones in the management and treatment of the disease. Vitamins are micronutrients that are vital for a healthy life. Some studies have linked fatty liver disease with vitamin deficiencies. However, the mechanism underlying these relationships has not been fully elucidated. Therefore, this review aims to discuss the role of vitamins in the pathogenesis of non-alcoholic fatty liver disease and explore their potential benefits in disease management.

Artan obezite prevalansına paralel olarak non alkolik yağlı karaciğer hastalığı birçok ülkede en yaygın karaciğer hastalığı haline gelmiştir. Non alkolik yağlı karaciğer hastalığı kardiyovasküler, hepatik, metabolik ve onkolojik sekellerinin yanı sıra karaciğer naklinin önde gelen nedeni haline geldiği için dünya çapında önemli bir morbidite ve mortalite nedenidir. Bu salgın ve sonuçları, dünyanın dört bir yanından uzmanları, hastalığın yönetimi ve tedavisi için etkili stratejiler belirlemeye yönlendirmiştir. Şu anda non alkolik yağlı karaciğer hastalığı için onaylanmış bir ilaç tedavisi yoktur. Bu nedenle diyet ve egzersiz gibi değiştirilebilir risk faktörleri hastalığın yönetimi ve tedavisinde köşe taşı olarak yerini korumaktadır. Vitaminler sağlıklı yaşam için hayati önem taşıyan mikro besin öğeleridir. Bazı çalışmalar yağlı karaciğer hastalığını vitamin eksiklikleri ile ilişkilendirse de bu ilişkilerin altında yatan mekanizma tam olarak aydınlatılamamıştır. Bu nedenle, bu derleme, vitaminlerin non alkolik yağlı karaciğer hastalığı patogenezindeki rolünü tartışmayı ve hastalık yönetiminde potansiyel faydalarını araştırmayı amaçlamaktadır.

Non alkolik yağlı karaciğer hastalığı Non alkolik yağlı karaciğer hastalığı Vitaminler Riboflavin Askorbik asid

Non-alcoholic fatty liver disease Vitamins Riboflavin Ascorbic acid

Yok

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