Our Therapeutic Approach to Idiopathic Granulomatous Mastitis

Year 2018, Volume: 23 Issue: 2, 88 - 92, 20.05.2018

Süleyman Bademler , Muhammed Zubeyr Ucuncu

https://doi.org/10.21673/anadoluklin.418775

Abstract

Aim: Granulomatous mastitis is a rare disease of the breast. Initial findings during admission can be mistaken for breast cancer. In this study, we aimed to present our experience with idiopathic granulomatous mastitis (IGM).

Materials and Methods: Patients who had been treated and followed up after a diagnosis of GM at the surgical clinic of the Istanbul University Institute of Oncology between 2007 and 2017 were categorized into two groups: those who had received steroid treatment only (Group 1), and those who had received steroids in combination with surgical treatment (Group 2). The groups were compared in terms of clinical and demographic characteristics and recurrence rates.

Results: We included a total of seventy-nine patients in our study. The mean patient age was 36.41±6.93 years and the mean follow-up 57.34±20.39 months. There was no significant difference between the two groups in terms of mean age, age at menarche, maternal age at first delivery, and the side involved (right, left, bilateral). The disease had recurred in 19 patients in Group 1 while no recurrence had been observed in Group 2 (p=0.001).

Discussion and Conclusion: IGM is a disease that is rare but easily mistakable for breast cancer. The diagnosis necessitates confirmation through a biopsy. Steroid therapy combined with surgery can be the first choice in the treatment of this disease, on which no consensus has yet been reached. Such combination is capable of reducing recurrence rates. 

Keywords

granulomatous mastitis, autoimmune disease

İdiyopatik Granülomatöz Mastitte Tedavi Yaklaşımımız

Abstract

Amaç: Granülomatöz mastit nadir görülen bir meme hastalığıdır. Müracaat bulguları meme kanseri ile karıştırılabilir. Bu çalışmada idiyopatik granülomatöz mastit (İGM) deneyimimizi sunmayı amaçladık.

Gereç ve Yöntemler: İstanbul Üniversitesi Onkoloji Enstitüsü Cerrahi Polikliniği’nde granülomatöz mastit tanısı ile 2007–2017 döneminde tedavi ve takip edilmiş olan hastalar, sadece steroit tedavisi görmüş olanlar (Grup 1) ve steroit tedavisine ilaveten cerrahi tedavi görmüş olanlar (Grup 2) olarak iki gruba ayrıldı. Gruplar klinik ve demografik özellikleri ile nüks oranları açısından karşılaştırıldı.

Bulgular: Çalışmamız kapsamına toplam 79 hasta alınmıştır. Hastaların ortalama yaşı 36,41±6,93 yıl, ortalama takip süresi 57,34±20,39 ay idi. İki grup arasında yaş ortalaması, ilk adet yaşı, ilk doğum yaşı ve tutulan taraf (sağ, sol, bilateral) yönünden anlamlı fark yoktu. Grup 1’de 19 hastada nüks gözlenirken Grup 2’de hiç nüks gözlenmemişti (p=0,001).

Tartışma ve Sonuç: İGM nadir görülen fakat meme kanseri ile karıştırılabilen bir hastalıktır. Tanıda biyopsi ile teyit şarttır. Tedavisi konusunda henüz konsensüse varılamamış olan bu hastalıkta steroit tedavisiyle cerrahi tedavinin kombine edilmesi ilk tercih olabilir. Bu kombinasyon ile nüks oranları azaltılabilmektedir. 

Keywords

granülomatöz mastit, otoimmün hastalıklar

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