In human embryos, the neocortex starts differentiating during 1.5, 2 months of gestation. Gyri start appearing around 5 months and continue their development to postnatal stages. During this time, a complex series of molecular and cellular events define topographic organization of the neocortex with primary sensory, motor areas, language areas, sensory association and cognitive areas. Neural activity joins the orchestration of molecular signaling and differentiation, in shaping the functional characteristics of anatomical connections. This lecture will focus on how studies in mouse cortical development are revealing the underlying principles of neocortical differentiation in the mammalian brain and how they are shining light upon developmental brain disorders in children.
Primary Language | English |
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Subjects | Health Care Administration |
Journal Section | Abstracts |
Authors | |
Publication Date | September 30, 2016 |
Published in Issue | Year 2016 Volume: 10 Issue: S2 |
Anatomy is the official journal of Turkish Society of Anatomy and Clinical Anatomy (TSACA).