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In vivo experimental models of schizophrenia: mechanisms, features, advantages, disadvantages

Year 2022, Volume: 16 Issue: 2, 114 - 123, 30.08.2022

Abstract

The experimental models of human diseases are indispensable research methods which are undesirable to be tested on humans. It is inevitable for researchers who continue their careers in the field of anatomy to be aware of these methods. Here, experimental schizophrenia models that can be used to reveal brain functions and also pathophysiology of schizophrenia are discussed. It is aimed to give general information about the features of the experimental schizophrenia models that can be used by researchers in morphological sciences; therein the references should be considered for the setup of the experimental schizophrenia models. In this review, in vivo model of schizophrenia used on etiopathogenesis, pathophysiology, drug discovery and behavioral analysis are represented. And also we briefly indicate the molecular mechanisms of the experimental models that mimic schizophrenia-like symptoms and its behavioral outputs.

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There are 96 citations in total.

Details

Primary Language English
Subjects Health Care Administration
Journal Section Reviews
Authors

Zeynep Mine Altunay This is me 0000-0002-7663-7417

Aysel Alphan This is me 0000-0001-9624-2036

Esat Adıgüzel This is me 0000-0002-1110-5786

Early Pub Date May 9, 2023
Publication Date August 30, 2022
Published in Issue Year 2022 Volume: 16 Issue: 2

Cite

APA Altunay, Z. M., Alphan, A., & Adıgüzel, E. (2022). In vivo experimental models of schizophrenia: mechanisms, features, advantages, disadvantages. Anatomy, 16(2), 114-123.
AMA Altunay ZM, Alphan A, Adıgüzel E. In vivo experimental models of schizophrenia: mechanisms, features, advantages, disadvantages. Anatomy. August 2022;16(2):114-123.
Chicago Altunay, Zeynep Mine, Aysel Alphan, and Esat Adıgüzel. “In Vivo Experimental Models of Schizophrenia: Mechanisms, Features, Advantages, Disadvantages”. Anatomy 16, no. 2 (August 2022): 114-23.
EndNote Altunay ZM, Alphan A, Adıgüzel E (August 1, 2022) In vivo experimental models of schizophrenia: mechanisms, features, advantages, disadvantages. Anatomy 16 2 114–123.
IEEE Z. M. Altunay, A. Alphan, and E. Adıgüzel, “In vivo experimental models of schizophrenia: mechanisms, features, advantages, disadvantages”, Anatomy, vol. 16, no. 2, pp. 114–123, 2022.
ISNAD Altunay, Zeynep Mine et al. “In Vivo Experimental Models of Schizophrenia: Mechanisms, Features, Advantages, Disadvantages”. Anatomy 16/2 (August 2022), 114-123.
JAMA Altunay ZM, Alphan A, Adıgüzel E. In vivo experimental models of schizophrenia: mechanisms, features, advantages, disadvantages. Anatomy. 2022;16:114–123.
MLA Altunay, Zeynep Mine et al. “In Vivo Experimental Models of Schizophrenia: Mechanisms, Features, Advantages, Disadvantages”. Anatomy, vol. 16, no. 2, 2022, pp. 114-23.
Vancouver Altunay ZM, Alphan A, Adıgüzel E. In vivo experimental models of schizophrenia: mechanisms, features, advantages, disadvantages. Anatomy. 2022;16(2):114-23.

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