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Cellular DNA content and clinicopathologic correlations in chondroid tumors

Year 1993, Volume: 27 Issue: 3, 163 - 165, 11.09.2006

Abstract

The process of differentiating between cartilage tumors is complex. Flow cytometric DNA analysis was performed on 23 chondroid tumors out of which 5 were enchondroma, 5 were Grade I, 4 were Grade II, 5 were Grade III and 4 were mesenchymal chandrosarcoma. Cellular DNA content, presynthetic growth phase, synthetic phase, postsynthetic phase and mitotic growth phases were determined for each case. Flow cytometry appears to provide a useful method to describe the DNA ploidy in cartilage tumors. In addition to nuclear DNA changes, proliferation phase values may also help in differential diagnosis of nuclear DNA changes, proliferation phase values may also help in differential diagnosis of these tumors.

Kıkırdak tümörlerinde hücresel DNA içeriği ile klinikopatolojik özelliklerin karşılaştırılması

Year 1993, Volume: 27 Issue: 3, 163 - 165, 11.09.2006

Abstract

Düşük grade li kondrosarkomların enkondromlarla ayırıcı tanısı, üzerinde tartışmaların halen sürdüğü bir konudur. Bu konuya çeşitli klinik, radyolojik ve histopatolojik yaklaşımlar getirilmektedir. Çalışmamızda 5 i enkondrom, 5 i Grade I kondrosarkom, 4 ü Grade II kondrosarkom, 5 i Grade III kondrosarkom, 4 ü mezenkimal kondrosarkom olmak üzere 23 kıkırdak tümörüne ait parafin bloklardan elde edilen kesitlere kollagenaz işlemi sonrası flow sitometrik analizi yapıldı. Hücresel DNA içeriği yanısıra presentetik büyüme fazı, sentetik faz, postsentetik faz, mitotik büyüme fazları her vaka için değerlendirildi. Bulgular klinikopatolojik özelliklerle birlikte değerlendirildiğinde DNA ploidisi ve proliferasyon fazı değerlerinin ayırıcı tanıya ışık tutan kriterler olduğu kanısına vardı.

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Details

Primary Language English
Journal Section Original Article
Authors

Sergülen Dervişoğlu This is me

Aslı Kasabaligil This is me

Altan Yalciner This is me

Buge Oz This is me

Suha Goksel This is me

Murat Hiz This is me

Ajlan Kasabaligil This is me

Gunay Girisken This is me

Publication Date September 11, 2006
Published in Issue Year 1993 Volume: 27 Issue: 3

Cite

APA Dervişoğlu, S., Kasabaligil, A., Yalciner, A., Oz, B., et al. (2006). Cellular DNA content and clinicopathologic correlations in chondroid tumors. Acta Orthopaedica Et Traumatologica Turcica, 27(3), 163-165. https://doi.org/10.3944/aott.v27i3.3147
AMA Dervişoğlu S, Kasabaligil A, Yalciner A, Oz B, Goksel S, Hiz M, Kasabaligil A, Girisken G. Cellular DNA content and clinicopathologic correlations in chondroid tumors. Acta Orthopaedica et Traumatologica Turcica. September 2006;27(3):163-165. doi:10.3944/aott.v27i3.3147
Chicago Dervişoğlu, Sergülen, Aslı Kasabaligil, Altan Yalciner, Buge Oz, Suha Goksel, Murat Hiz, Ajlan Kasabaligil, and Gunay Girisken. “Cellular DNA Content and Clinicopathologic Correlations in Chondroid Tumors”. Acta Orthopaedica Et Traumatologica Turcica 27, no. 3 (September 2006): 163-65. https://doi.org/10.3944/aott.v27i3.3147.
EndNote Dervişoğlu S, Kasabaligil A, Yalciner A, Oz B, Goksel S, Hiz M, Kasabaligil A, Girisken G (September 1, 2006) Cellular DNA content and clinicopathologic correlations in chondroid tumors. Acta Orthopaedica et Traumatologica Turcica 27 3 163–165.
IEEE S. Dervişoğlu, A. Kasabaligil, A. Yalciner, B. Oz, S. Goksel, M. Hiz, A. Kasabaligil, and G. Girisken, “Cellular DNA content and clinicopathologic correlations in chondroid tumors”, Acta Orthopaedica et Traumatologica Turcica, vol. 27, no. 3, pp. 163–165, 2006, doi: 10.3944/aott.v27i3.3147.
ISNAD Dervişoğlu, Sergülen et al. “Cellular DNA Content and Clinicopathologic Correlations in Chondroid Tumors”. Acta Orthopaedica et Traumatologica Turcica 27/3 (September 2006), 163-165. https://doi.org/10.3944/aott.v27i3.3147.
JAMA Dervişoğlu S, Kasabaligil A, Yalciner A, Oz B, Goksel S, Hiz M, Kasabaligil A, Girisken G. Cellular DNA content and clinicopathologic correlations in chondroid tumors. Acta Orthopaedica et Traumatologica Turcica. 2006;27:163–165.
MLA Dervişoğlu, Sergülen et al. “Cellular DNA Content and Clinicopathologic Correlations in Chondroid Tumors”. Acta Orthopaedica Et Traumatologica Turcica, vol. 27, no. 3, 2006, pp. 163-5, doi:10.3944/aott.v27i3.3147.
Vancouver Dervişoğlu S, Kasabaligil A, Yalciner A, Oz B, Goksel S, Hiz M, Kasabaligil A, Girisken G. Cellular DNA content and clinicopathologic correlations in chondroid tumors. Acta Orthopaedica et Traumatologica Turcica. 2006;27(3):163-5.