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Miksoinflamatuar fibroblastik sarkom: Olgu sunumu

Year 2013, Volume: 47 Issue: 6, 436 - 439, 07.02.2014

Abstract

Miksoinflamatuar fibroblastik sarkom (MİFS), son zamanlarda tanımlanmış olan ve seyrek görülen, düşük dereceli bir sarkomdur. Genellikle alt veya üst ekstremitelerde yerleşen MİFS, klinikte iyi huylu kistik kitle bulgusu verirken fibroblastik miksoid stroma içerisinde iğsi ya da atipik görünümlü hücreler ile mikst türde inflamatuar infiltrattan oluşur. Radyolojik ve makroskobik görüntüsü genellikle düzensiz sınırlı lobüle kitle şeklindedir. Çalışmamızda, daha önceden tanımlanan özelliklerden farklı şekilde düzgün sınırlı ve sadece orta bölümde neoplastik hücreler saptanan tümöral bir kitle sunulmaktadır. Klinik olarak iyi huylu kitlelerden ayrılması oldukça zor olan MİFS olgularında, ekstremite yerleşimli lezyonlarda habaset olasılığı her zaman akılda bulundurulmalıdır.

References

  • Narváez JA, Martinez S, Dodd LG, Brigman BE. Acral myxoinflammatory fibroblastic sarcomas: MRI findings in four cases. AJR Am J Roentgenol 2007;188:1302-5.
  • Kovarik CL, Barrett T, Auerbach A, Cassarino DS. Acral myxoinflammatory fibroblastic sarcoma: case series and immunohistochemical analysis. J Cutan Pathol 2008;35:192
  • Flooks R, Vanacker A, Van Dorpe J, Smet B, Vandewiele V, De Schoenmakere G, et al. Acral myxoinflammatory fibroblastic sarcoma in a renal transplant patient: a case report. Transplant Proc 2009;41:3437-9.
  • Prescott RJ, Husain EA, Abdellaoui A, Al-Mahmoud RM, Khan M, Salman WD, et al. Superficial acral fibromyxoma: a clinicopathological study of new 41 cases from the U.K.: should myxoma (NOS) and fibroma (NOS) continue as part of 21st-century reporting? Br J Dermatol 2008;159:1315-21.
  • Meis-Kindblom JM, Kindblom LG. Myxoinflammatory fibroblastic sarcoma. In: Fletcher CD, Unni KK, Mertens F, editors. WHO classification of classification of tumors. Pathology and genetics of tumors of soft tissue and bone. Lyon: IARC Press; 2002. p. 96-7.
  • Premalata CS, Rama Rao C, Padma M, Vijaykumar M. Myxoinflammatory fibroblastic sarcoma – report of a rare case at an unusual site with review of the literature. Int J Dermatol 2008;47,68-71.
  • Sakaki M, Hirokawa M, Wakatsuki S, Sano T, Endo K, Fujii Y, et al. Acral myxoinflammatory fibroblastic sarcoma: a report of f›ve cases and review of the literature. Virchows Arch 2003;442:25-30.
  • Alkuwari E, Gravel DH. A 30-year-old man with a soft tissue mass on the right elbow. Inflammatory myxohyaline tumor of the distal extremities with prominent eosinophilic infiltrate. Arch Pathol Lab Med 2006;130:e35-6.
  • Montgomery EA, Devaney KO, Giordano TJ, Weiss SW. Inflammatory myxohyaline tumor of distal extremities with virocyte or Reed-Sternberg-like cells: a distinctive lesion with features simulating inflammatory conditions, Hodgkin's disease, and various sarcomas. Mod Pathol 1998;11:384-91.
  • Meis-Kindblom JM, Kindblom LG. Acral myxoinflammatory fibroblastic sarcoma: a low-grade tumor of the hands and feet. Am J Surg Pathol 1998;22:911-24.
  • Michal M. Inflammatory myxoid tumor of the soft parts with bizarre giant cells. Pathol Res Pract 1998;194:529-33.
  • Jurciç V, Zidar A, Montiel MD, Frkoviç-Grazio S, Nayler SJ, Cooper K, et al. Myxoinflammatory fibroblastic sarcoma: a tumor not restricted to acral sites. Ann Diagn Pathol 2002; 6:272-80.
  • Monson E, Vancourt R, Dawson J. Myxoinflammatory fibroblastic sarcoma: a case report and review of the literature. J Foot Ankle Surg 2010;49:86.
  • Kobayashi E, Kawai A, Endo M, Suehara Y, Takeda K, Nakatani F, et al. Myxoinflammatory fibroblastic sarcoma. J Orthop Sci 2008;13:566-71.
  • Tateishi U, Hasegawa T, Onaya H, Satake M, Arai Y, Moriyama N. Myxoinflammatory fibroblastic sarcoma: MR appearance and pathologic correlation. AJR Am J Roentgenol 2005;184:1749-53.
  • Lang JE, Dodd L, Martinez S, Brigman BE. Case reports: acral myxoinflammatory fibroblastic sarcoma: a report of five cases and literature review. Clin Orthop Relat Res 2006; (445):254-60.

Myxoinflammatory fibroblastic sarcoma: a case report

Year 2013, Volume: 47 Issue: 6, 436 - 439, 07.02.2014

Abstract

Myxoinflammatory fibroblastic sarcoma (MIFS) is a recently described, rare low-grade sarcoma. Generally located in the upper and lower extremities, MIFS clinically mimics a benign cystic mass and is composed of spindle-like or atypical cells and mixed inflammatory infiltrates located in the fibroblastic myxoid stroma. Radiologic images and macroscopic appearance generally resemble a lobulated mass with irregular margins. We present a case of a tumoral mass with neoplastic cells at the center and a smooth surface with a previously undefined appearance. Myxoinflammatory fibroblastic sarcoma is significantly difficult to distinguish clinically from benign lesions and the surgeon should consider the possibility of malignancy in lesions located at the extremities.

References

  • Narváez JA, Martinez S, Dodd LG, Brigman BE. Acral myxoinflammatory fibroblastic sarcomas: MRI findings in four cases. AJR Am J Roentgenol 2007;188:1302-5.
  • Kovarik CL, Barrett T, Auerbach A, Cassarino DS. Acral myxoinflammatory fibroblastic sarcoma: case series and immunohistochemical analysis. J Cutan Pathol 2008;35:192
  • Flooks R, Vanacker A, Van Dorpe J, Smet B, Vandewiele V, De Schoenmakere G, et al. Acral myxoinflammatory fibroblastic sarcoma in a renal transplant patient: a case report. Transplant Proc 2009;41:3437-9.
  • Prescott RJ, Husain EA, Abdellaoui A, Al-Mahmoud RM, Khan M, Salman WD, et al. Superficial acral fibromyxoma: a clinicopathological study of new 41 cases from the U.K.: should myxoma (NOS) and fibroma (NOS) continue as part of 21st-century reporting? Br J Dermatol 2008;159:1315-21.
  • Meis-Kindblom JM, Kindblom LG. Myxoinflammatory fibroblastic sarcoma. In: Fletcher CD, Unni KK, Mertens F, editors. WHO classification of classification of tumors. Pathology and genetics of tumors of soft tissue and bone. Lyon: IARC Press; 2002. p. 96-7.
  • Premalata CS, Rama Rao C, Padma M, Vijaykumar M. Myxoinflammatory fibroblastic sarcoma – report of a rare case at an unusual site with review of the literature. Int J Dermatol 2008;47,68-71.
  • Sakaki M, Hirokawa M, Wakatsuki S, Sano T, Endo K, Fujii Y, et al. Acral myxoinflammatory fibroblastic sarcoma: a report of f›ve cases and review of the literature. Virchows Arch 2003;442:25-30.
  • Alkuwari E, Gravel DH. A 30-year-old man with a soft tissue mass on the right elbow. Inflammatory myxohyaline tumor of the distal extremities with prominent eosinophilic infiltrate. Arch Pathol Lab Med 2006;130:e35-6.
  • Montgomery EA, Devaney KO, Giordano TJ, Weiss SW. Inflammatory myxohyaline tumor of distal extremities with virocyte or Reed-Sternberg-like cells: a distinctive lesion with features simulating inflammatory conditions, Hodgkin's disease, and various sarcomas. Mod Pathol 1998;11:384-91.
  • Meis-Kindblom JM, Kindblom LG. Acral myxoinflammatory fibroblastic sarcoma: a low-grade tumor of the hands and feet. Am J Surg Pathol 1998;22:911-24.
  • Michal M. Inflammatory myxoid tumor of the soft parts with bizarre giant cells. Pathol Res Pract 1998;194:529-33.
  • Jurciç V, Zidar A, Montiel MD, Frkoviç-Grazio S, Nayler SJ, Cooper K, et al. Myxoinflammatory fibroblastic sarcoma: a tumor not restricted to acral sites. Ann Diagn Pathol 2002; 6:272-80.
  • Monson E, Vancourt R, Dawson J. Myxoinflammatory fibroblastic sarcoma: a case report and review of the literature. J Foot Ankle Surg 2010;49:86.
  • Kobayashi E, Kawai A, Endo M, Suehara Y, Takeda K, Nakatani F, et al. Myxoinflammatory fibroblastic sarcoma. J Orthop Sci 2008;13:566-71.
  • Tateishi U, Hasegawa T, Onaya H, Satake M, Arai Y, Moriyama N. Myxoinflammatory fibroblastic sarcoma: MR appearance and pathologic correlation. AJR Am J Roentgenol 2005;184:1749-53.
  • Lang JE, Dodd L, Martinez S, Brigman BE. Case reports: acral myxoinflammatory fibroblastic sarcoma: a report of five cases and literature review. Clin Orthop Relat Res 2006; (445):254-60.
There are 16 citations in total.

Details

Primary Language English
Subjects Health Care Administration
Journal Section Case Report
Authors

Ozge Ertener This is me

Burcin Tuna This is me

Omer Akcali This is me

Kutsal Yorukoglu This is me

Publication Date February 7, 2014
Published in Issue Year 2013 Volume: 47 Issue: 6

Cite

APA Ertener, O., Tuna, B., Akcali, O., Yorukoglu, K. (2014). Myxoinflammatory fibroblastic sarcoma: a case report. Acta Orthopaedica Et Traumatologica Turcica, 47(6), 436-439.
AMA Ertener O, Tuna B, Akcali O, Yorukoglu K. Myxoinflammatory fibroblastic sarcoma: a case report. Acta Orthopaedica et Traumatologica Turcica. February 2014;47(6):436-439.
Chicago Ertener, Ozge, Burcin Tuna, Omer Akcali, and Kutsal Yorukoglu. “Myxoinflammatory Fibroblastic Sarcoma: A Case Report”. Acta Orthopaedica Et Traumatologica Turcica 47, no. 6 (February 2014): 436-39.
EndNote Ertener O, Tuna B, Akcali O, Yorukoglu K (February 1, 2014) Myxoinflammatory fibroblastic sarcoma: a case report. Acta Orthopaedica et Traumatologica Turcica 47 6 436–439.
IEEE O. Ertener, B. Tuna, O. Akcali, and K. Yorukoglu, “Myxoinflammatory fibroblastic sarcoma: a case report”, Acta Orthopaedica et Traumatologica Turcica, vol. 47, no. 6, pp. 436–439, 2014.
ISNAD Ertener, Ozge et al. “Myxoinflammatory Fibroblastic Sarcoma: A Case Report”. Acta Orthopaedica et Traumatologica Turcica 47/6 (February 2014), 436-439.
JAMA Ertener O, Tuna B, Akcali O, Yorukoglu K. Myxoinflammatory fibroblastic sarcoma: a case report. Acta Orthopaedica et Traumatologica Turcica. 2014;47:436–439.
MLA Ertener, Ozge et al. “Myxoinflammatory Fibroblastic Sarcoma: A Case Report”. Acta Orthopaedica Et Traumatologica Turcica, vol. 47, no. 6, 2014, pp. 436-9.
Vancouver Ertener O, Tuna B, Akcali O, Yorukoglu K. Myxoinflammatory fibroblastic sarcoma: a case report. Acta Orthopaedica et Traumatologica Turcica. 2014;47(6):436-9.