Case Report
BibTex RIS Cite

Statin kullanımına bağlı pankreatik enzim yükselmesi-vaka sunumu

Year 2021, Volume: 2 Issue: 3, 25 - 26, 31.12.2021

Abstract

Statin kullanımıyla birlikte kas ağrıları, karaciğer enzim yüksekliği ve rabdomyoliz görülebilmektedir. Pankreas hasarı ve buna bağlı lipaz yüksekliği statinin nadir görülen ciddi istenmeyen etkilerindendir. Bu vaka sunumunda, statin kullanımından sonra lipaz seviyelerinde yükselme görülen, serebrovasküler hastalık ve prostat kanseri öyküsü bulunan 61 yaşında bir erkek hastayı değerlendirdik. Bu hastada olası pankreatik hasar görülen hastada farklı statin gruplarını denedik ve statin kullanımına bağlı olası pankreas hasar mekanizmalarını ele aldık.

References

  • 1. Jaya Krishna Chintanaboina and Deepa Gopavaram, Recurrent Acute Pancreatitis Probably Induced by Rosuvastatin Therapy: A Case Report Hindawi Publishing Corporation Case Reports in Medicine Volume 2012, Article ID 973279, 4 pages.
  • 2. G.Miltiades, A.Anthopoulos & M.Elisaf (2003), Acute pancreatitis possibly associated with combined salicylate and atorvastatin therapy: JOP. J Pancreas (Online) 4(1):20-21.
  • 3. S.Singh,A.Nautiyal,andJ.G.Dolan,Recurrentacute pancreatitis possibly induced by atorvastatin and rosuvastatin. Is statin-induced pancreatit is a class effect? JOP. J Pancreas (Online) 2004; 5(6):502-504.
  • 4. J.L.Johnson and I.B.Loomis, A case of simvastatin-associated pancreatitis and review of statin-associated pancreatitis, Pharmacotherapy 2006;26(3):414–422.
  • 5. Deshpande PR, Khera K, Thunga G, Hande M, Gouda ST, Nagappa AN. Atorvastatin-induced acute pancreatitis. J Pharmacol Pharmaco ther. 2011;2(1):40–42.
  • 6. Nison Badalov et al. Drug-Induced Acute Pancreatitis: An Evidence-Based Review: CLINICAL GASTROENTEROLOGY AND HEPATOLOGY 2007;5:648–661.
  • 7. Jun Gong et al. Statins and pancreatic cancer (Review): ONCOLOGY LETTERS 13: 1035-1040, 2017.

A case of pancreatic enzyme elevation due to use of statins

Year 2021, Volume: 2 Issue: 3, 25 - 26, 31.12.2021

Abstract

It is well known that statin usage is linked with side effects such as miyalgias, hepatic enzyme elevation and rabdomyolisis. Pancreatic injury and lipase elevation may be a rare side effect of statins. In this case report, we present a 61-year-old male with the history of cerebrovascular disease (CVD) and prostate cancer which experienced elevation of lipase levels after use of statins. We tried different types of statins for the patients condition of pancreatic injury and in this case report, the possible reasons of statin induced pancreatic injury are underlined.

References

  • 1. Jaya Krishna Chintanaboina and Deepa Gopavaram, Recurrent Acute Pancreatitis Probably Induced by Rosuvastatin Therapy: A Case Report Hindawi Publishing Corporation Case Reports in Medicine Volume 2012, Article ID 973279, 4 pages.
  • 2. G.Miltiades, A.Anthopoulos & M.Elisaf (2003), Acute pancreatitis possibly associated with combined salicylate and atorvastatin therapy: JOP. J Pancreas (Online) 4(1):20-21.
  • 3. S.Singh,A.Nautiyal,andJ.G.Dolan,Recurrentacute pancreatitis possibly induced by atorvastatin and rosuvastatin. Is statin-induced pancreatit is a class effect? JOP. J Pancreas (Online) 2004; 5(6):502-504.
  • 4. J.L.Johnson and I.B.Loomis, A case of simvastatin-associated pancreatitis and review of statin-associated pancreatitis, Pharmacotherapy 2006;26(3):414–422.
  • 5. Deshpande PR, Khera K, Thunga G, Hande M, Gouda ST, Nagappa AN. Atorvastatin-induced acute pancreatitis. J Pharmacol Pharmaco ther. 2011;2(1):40–42.
  • 6. Nison Badalov et al. Drug-Induced Acute Pancreatitis: An Evidence-Based Review: CLINICAL GASTROENTEROLOGY AND HEPATOLOGY 2007;5:648–661.
  • 7. Jun Gong et al. Statins and pancreatic cancer (Review): ONCOLOGY LETTERS 13: 1035-1040, 2017.
There are 7 citations in total.

Details

Primary Language English
Subjects Clinical Sciences
Journal Section Olgu Sunumu
Authors

Bilge Karadeniz 0000-0003-3584-1128

Mert Kaşkal 0000-0002-2220-8529

Publication Date December 31, 2021
Submission Date March 8, 2021
Acceptance Date May 14, 2021
Published in Issue Year 2021 Volume: 2 Issue: 3

Cite