Year 2021, Volume 31 , Issue 1, Pages 124 - 129 2021-01-15

OLİGODONTİNİN GENETİK TEMELİ

Canan BAYRAKTAR [1] , Zuhal KIRZIOĞLU [2]


Oligodonti, çeşitli nedenlerle altı ya da daha fazla dişin oluşmamasına bağlı izlenen bir sayı anomalisidir. Görülme sıklığı kıtalara, toplumlara ve cinsiyetlere göre farklılık göstermektedir. Diş gelişimi ağırlıklı olarak genetik kontrolü altında ilerlemektedir. Diş gelişimi sırasında 200'den fazla gen rol oynamakta ve bu genlerde meydana gelen mutasyonların, oligodontiye neden olduğu düşünülmektedir. Oligodontiye neden olan genlerde, bireyler arası önemli varyasyonlar bulunmakta ve oluşan gen mutasyonlarının oligodontiyle birlikte bazı anomalilere ve kanserlere neden olduğu ifade edilmektedir. Oligodontili bireylerde etiyolojinin belirlenmesi, bu durumu etkileyen genlerin, ileride neden olabileceği çeşitli sağlık problemlerinin de önüne geçilmesi açısından önem taşımaktadır. Derlememiz, daha önceki yayınlarda bildirilmiş olan oligodonti ile ilişkili insan genomundaki mutasyonları gözden geçirmek ve dahil olan farklı genler hakkında gene özgü detaylar sağlamak için hazırlanmıştır. Anahtar Kelimeler: Diş Eksikliği, Etiyoloji, Genetik

GENETIC BASIS OF OLIGODONTIA

Abstract

Oligodontia is a number anomaly that is observed due to the absence of six or more teeth for various reason. The prevalance of oligodontia have varies according to continents, societies and genders. Tooth development have proceed predominantly genetic control. More than 200 genes have play a role during dental development, and mutations in these genes are thought to cause oligodontia. There are important inter-individual differences in the genes that cause oligodontia, and it is stated that the gene mutations that cause oligodontia cause some anomalies and cancers. The determination of the etiology in individuals with oligodontia is important in order to prevent the various health problems that may be caused by the genes that affect this condition. Our review was prepared to review mutations in the human genome associated with oligodontia reported in previous publications and to provide gene-specific details about the different genes involved. Keywords: Tooth Agenesis, Etiology, Genetics

Diş Eksikliği, Etiyoloji, Genetik
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Primary Language tr
Subjects Dentistry, Oral Surgery and Medicine
Journal Section Derleme
Authors

Orcid: 0000-0003-1388-1778
Author: Canan BAYRAKTAR
Institution: SÜLEYMAN DEMİREL ÜNİVERSİTESİ, DİŞ HEKİMLİĞİ FAKÜLTESİ
Country: Andorra


Orcid: 0000-0002-3726-2392
Author: Zuhal KIRZIOĞLU
Institution: SÜLEYMAN DEMİREL ÜNİVERSİTESİ, DİŞ HEKİMLİĞİ FAKÜLTESİ
Country: Andorra


Dates

Publication Date : January 15, 2021

Bibtex @review { ataunidfd718002, journal = {Atatürk Üniversitesi Diş Hekimliği Fakültesi Dergisi}, issn = {1300-9044}, eissn = {2667-5161}, address = {}, publisher = {Ataturk University}, year = {2021}, volume = {31}, pages = {124 - 129}, doi = {10.17567/ataunidfd.718002}, title = {OLİGODONTİNİN GENETİK TEMELİ}, key = {cite}, author = {Bayraktar, Canan and Kırzıoğlu, Zuhal} }
APA Bayraktar, C , Kırzıoğlu, Z . (2021). OLİGODONTİNİN GENETİK TEMELİ . Atatürk Üniversitesi Diş Hekimliği Fakültesi Dergisi , 31 (1) , 124-129 . DOI: 10.17567/ataunidfd.718002
MLA Bayraktar, C , Kırzıoğlu, Z . "OLİGODONTİNİN GENETİK TEMELİ" . Atatürk Üniversitesi Diş Hekimliği Fakültesi Dergisi 31 (2021 ): 124-129 <https://dergipark.org.tr/en/pub/ataunidfd/issue/60082/718002>
Chicago Bayraktar, C , Kırzıoğlu, Z . "OLİGODONTİNİN GENETİK TEMELİ". Atatürk Üniversitesi Diş Hekimliği Fakültesi Dergisi 31 (2021 ): 124-129
RIS TY - JOUR T1 - OLİGODONTİNİN GENETİK TEMELİ AU - Canan Bayraktar , Zuhal Kırzıoğlu Y1 - 2021 PY - 2021 N1 - doi: 10.17567/ataunidfd.718002 DO - 10.17567/ataunidfd.718002 T2 - Atatürk Üniversitesi Diş Hekimliği Fakültesi Dergisi JF - Journal JO - JOR SP - 124 EP - 129 VL - 31 IS - 1 SN - 1300-9044-2667-5161 M3 - doi: 10.17567/ataunidfd.718002 UR - https://doi.org/10.17567/ataunidfd.718002 Y2 - 2020 ER -
EndNote %0 Atatürk Üniversitesi Diş Hekimliği Fakültesi Dergisi OLİGODONTİNİN GENETİK TEMELİ %A Canan Bayraktar , Zuhal Kırzıoğlu %T OLİGODONTİNİN GENETİK TEMELİ %D 2021 %J Atatürk Üniversitesi Diş Hekimliği Fakültesi Dergisi %P 1300-9044-2667-5161 %V 31 %N 1 %R doi: 10.17567/ataunidfd.718002 %U 10.17567/ataunidfd.718002
ISNAD Bayraktar, Canan , Kırzıoğlu, Zuhal . "OLİGODONTİNİN GENETİK TEMELİ". Atatürk Üniversitesi Diş Hekimliği Fakültesi Dergisi 31 / 1 (January 2021): 124-129 . https://doi.org/10.17567/ataunidfd.718002
AMA Bayraktar C , Kırzıoğlu Z . OLİGODONTİNİN GENETİK TEMELİ. Ata Diş Hek Fak Derg. 2021; 31(1): 124-129.
Vancouver Bayraktar C , Kırzıoğlu Z . OLİGODONTİNİN GENETİK TEMELİ. Atatürk Üniversitesi Diş Hekimliği Fakültesi Dergisi. 2021; 31(1): 124-129.
IEEE C. Bayraktar and Z. Kırzıoğlu , "OLİGODONTİNİN GENETİK TEMELİ", Atatürk Üniversitesi Diş Hekimliği Fakültesi Dergisi, vol. 31, no. 1, pp. 124-129, Jan. 2021, doi:10.17567/ataunidfd.718002