Secnidazol Treatment to Improve Milk Yield in Sheep with Giardiasis

Year 2014, Volume: 9 Issue: 2, 0 - , 10.10.2014

Deniz Alıç Ural , Adnan Ayan Nuran Aysul , Canberk Balıkcı Kerem Ural

https://doi.org/10.17094/avbd.91674

Abstract

The purpose of this multidiciplinary (agricultural and veterinary fields) study was to assess the effect of single secnidazol treatment on milk production in dairy ewes naturally infected with Giardia duodenalis. Thirty dairy ewes with Giardiasis, were enrolled into 3 equal groups and Groups I and II were treated with secnidazole at a single dose rate of 10 mg/kg or 30 mg/kg, respectively, perorally and G III ewes were controls. Throughout the study ewes in G III remained positive for Giardiasis, with some of them showed an increase without statistical significance in cyst counts on day 10 (ranged 1300241650) compared to the initial values (ranged between 5600-274600). The least square means and standard error of means of cyst excretion on D0 and D10 revealed that there was a significant reduction (P<0.001) in cyst reduction in GI and GII animals. Both group GI and GII ewes produced significantly more milk than group G III ones (P<0.001). The change of mean milk yield over time was statistically significant (P<0.001) among group GI and GII ewes; besides a statistically significant (P<0.001) reduction in the mean milk yield of group GIII ewes was observed. Given the efficacy of secnidazol treatment for cyst reduction and increased milk yield, it may be safely suggested that Giardiasis adversely affects the production of the infested animals.

Keywords

Giardiasis, Milk yield, Secnidazol, Sheep.

Secnidazol Treatment to Improve Milk Yield in Sheep with Giardiasis

Abstract

Giardia duodenalis ile doğal enfekte sütçü koyunlar üzerine yapılan bu multidisipliner çalışmada tek dozda seknidazol sağaltım etkinliğinin belirlenmesi amaçlanmıştır. Giardiasisli 30 sütçü koyun, 3 eşit gruba ayrılmıştır. Grup I ve Grup II’de tek doz seknidazol (sırasıyla 10 mg/kg, 30 mg/kg p.o.) sağaltımı uygulanmış ve Grup III kontrol grubu olarak belirlenmiştir. Çalışma süresince kontrol grubu olan grup III’deki sütçü koyunlar Giardia yönünden pozitivitelerini sürdürmüşlerdir ve başlangıç değerleri (5600-274600) ile 10. gündeki (1300-241650) kist sayıları karşılaştırıldığında gruptaki bazı hayvanlarda istatistiksel önemi bulunmayan artış gözlenlenmiştir. Sıfırıncı ve 10. günlerindeki kist saçılımının en küçük kare ve standart hata değerlerine bakıldığında farklı doz seknidazol ile sağaltımı yapılan GI ve GII’deki hayvanların kist atılımında önemli derecede azalma (P<0.001) olduğu görülmüştür. Gerek GI, gerekse GII’deki koyunlar, GIII’dekilere oranla istatistiksel olarak belirgin şekilde daha fazla süt üretmişlerdir (P<0.001). Süt verimi ortalamalarında GI ve GII’de istatistiksel olarak anlamlı (P<0.001) değişiklikler saptanırken, GIII’deki koyunlarda süt veriminde azalma (P<0.001) gözlemlendi. Seknidazol sağaltımının kist atılımında azalma ve süt veriminde artış gibi etkileri nedeniyle; Giardiasis’in, enfekte koyunların süt verimini olumsuz derecede etkilediği rahatlıkla söylenebilinir.

Keywords

Giardiasis, Koyun, Seknidazol, Süt verimi.

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