Ankara Üniversitesi Tıp Fakültesi Mecmuası 0365-8104 1307-5608 Ankara University Medical Bacteriology Tıbbi Bakteriyoloji Pencere Dönemınde Bır Akut Vıral Hepatıtıs B Olgusu Case Of Acute Vıral Hepatıtıs B In Wındow Perıod Tekeli Emin ANKARA ÜNİVERSİTESİ, SAĞLIK BİLİMLERİ ENSTİTÜSÜ, MİKROBİYOLOJİ VE KLİNİK MİKROBİYOLOJİ (YL) (TEZLİ) 12 31 1989 42 4 517 520 10 01 1989 12 31 1989 Copyright © 1947, Ankara Üniversitesi Tıp Fakültesi Mecmuası 1947 Ankara Üniversitesi Tıp Fakültesi Mecmuası

30 yasinda erkek hasta klinigimize halsizlik, istahsizlik, bulanti,kusma, deri ve skleralarida ikter, idrar renginin koyulasmasi sikayetleri ile basvurdu. Fizik muayenesinde deri ve skleralar ikterik oluporta derecede hepatomegalisi mevcuttu. Daboratuvar bulgulan viralhepatit ile uyumlu olan hastanin markerleri ELISA yéntemi ile incelendi ve vak’anm pencere (window) déneminde A. viral hepatit Bvak’asi oldugu sonucuna varildi.

A 30 year-old male patient was admitted to the hospital with complaints of malaise, nausea, womiting, icter in skin and scleras and colour change of his urine. On his physical examination the skin and scleras were icteric and there was a mild hepatomegaly. The laborotory findings were consistent with hepatitis. The investigation ofviral markers by ELISA technic revealed a case of viral hepatitis B in window periodu

 malaise nausea womiting idrar renginin koyulasmasi skleralarida ikter kusma 1. Aicawa T, Sairenji H. : Seroconversion from hepatitis Be antijen to anti HBe n A. Hep. B virus inf. N. Eng. J. Med. 298 : 439 (1978). 2. Aldersvile J, Frosna G : Hepatitis Be antigen and antibody radioimmunoassay in a Hepatitis B surface ag. positive hepatitis J. inf. dis. 141 : 293, 1980. Hoofnagle Gerald. Clinic asp. of. inf. disease. 1985. Mandel 3. Howard F, Taswell. : Viral hepatitis diagn. test using Anti HBcIgM. Lab. Med. 1985. Krugman S : Viral hepatitis type B DNA polymerase activity and antibody to hepatitis B core ant. N. Eng. J. Med. 290 : 1331, 1974. 4. Krugman 5, Overbay LR: Viral hepatitis type B studies on natural history and prevention reexamined. N. Eng. Jour. of Med. 300 : 101, 1979 . Kryger P, Aldershvile : Acute type B hepatitis among HBsAg negative patients detected by antiHBcIgM. Hepatology, 2 : 50-3, 1982. Lemon SM, Gates NI. : IgM antibody to HB core ant. as a diagn. p. of. an inf. with HBV. The jour. of. inf. dis. vol : 143, June 1981. 5. Mushward J, Polesky : Interpretation of various serological profiles of Hepatitis B Virus inf. Am. J. Clin. Path. 1981, 76-77 : 3-7. Overby, LR, Mushahwar ik, Hepatitis Be antigen and its correlation with other serologic markers. Inf. Immun. 24. 352, 1979.