Ankara Üniversitesi Tıp Fakültesi Mecmuası

0365-8104 1307-5608

Ankara University

Brain and Nerve Surgery (Neurosurgery)

Beyin ve Sinir Cerrahisi (Nöroşirurji)

The Effect of Temoral Lobe On Sexual Functions

TEMPORAL LOBUN SEKSÜEL FONKSİYONLAR ÜZERİNE ETKİSİ*

Deda

Halık

Ankara Üniversitesi Tıp Fakültesi Nöroşirürji Anabilim Dalı

12 31 1989

42 4 525 534 10 01 1989 12 30 1989

1947

Ankara Üniversitesi Tıp Fakültesi Mecmuası

Temporal lobe modulates sexual, reproductive, and neuroendocrine function in animals. However so far, it has not been shown by ebjective tests, that what kind of lesions of the temporal lobe results in hypo or hypersexuality and which part of the temporal lobe plays a role in sexual funetions in men.Sleep and NPT monitorization were held on in six patients with temporal lobe tumors in order to investigate the effect of temporal lobe on sexual functions the Neurosurgical Department of the Üniversity of Ankara, Faculty of Medicine.The results were as follows; hypersexuality in one patient, hyposexuality in 2 patients, impotence in 2 patients, and normosexuality in one patient. The endocrinologic tests in these patients were as follows; in 4 patients PRL, and in one patient FSH and LH were found to be increased. The testosterone levels of these 6 patients were normal.In conclusion, we can say that temporal lobe is effective on sexual and neuroendocrinologic functions. Key words : Temporal lobe, Impotence, NPT, Sexual Functions

Temporal lob lezyonlarının seksüel fonksiyonlar üzerinde etkilerini araştırmak amacı ile temporal lob lezyonu olan 6 hastanın 2 gece boyunca yapılan NPT monitörizasyonu sonucunda 1 hastada hiperseksüalite, 2 hastada hiposeksüalite, 2 hastada impotans tespit edilmiş ve 1 hastada normoseksüel olarak bulunmuştur.Hastaların yapılan hormon incelemelerinde 4 hastada PRL, 1 hastada ise FSH ve LH düzeyi yüksek olarak bulunmuştur. Bu hastaların testesteron düzeyleri ise normal olarak tespit edilmiştir. Bu bulgularla; temporal lobun, objektif kriterlerin ışığında, literatürle uyumlu olarak seksüel ve nöroendokrin fonksiyonlar üzerinde etkili olduğunu ve gerek seksüel ve gerekse nöroendokrin bozukluğu olan hastalarda bu bulguları açıklayacak bir patoloji tespit edilemediği takdirde temporal lobun mutlaka, detaylı olarak incelenmesi gerektiğini söyliyebiliriz.

Temporal lobe testosterone

temporal lob testesteron

1. Berkovic S.F, Temporal lobe epilepsy in hyposexual men. The Lancet March 17, 622-623, 1984,

2. Beutler LE, et al,, MMPI and MIT discriminators of biogenic and psychogenic impotence. Journal of Consulting and Clinical Psycology vol 43, No 6 899-903, 1975.

3. Blumer D., Walker E., Sexual behavior in temporal lobe epilepsy. Arch Neurol Vol 16, 37-43, 1967.

4.Blumer D., Hypersexual Episodes in Temporal Lobe Epilepsy., Amer J. Psychiat. 126 : 8, 1099-1105, 1970.

5.Dewsbury D.A, et al., Effects of Hippocampal lesions on the copulatory behavior of male rats., Physiology and Behavior. vol 3, pp. 651-656, 1968.

6.Ertekin C., and Reel F., Bulbocavernosus refleks in normal.nen and in patients with neurogenic bladder and/or impotence,, Journal of the Neurological Sciences, 28 : 1-15, 1976.

7.Fisher C. et al, Evaluation of nocturnal penile tumescence in the differential diagnosis of sexual impotence. Arch Gen Psychiatry Vol 36, April, 431-437, 1979.

8.Hierons R., and Saunders M., Impotence in patients with temporal-lobe lesions.,The Lancet october 8, 761-763, 1966.

9.Hunter R., Transvestism, impotence and temporal lobe dysfunction., J. neurol. Sci 4 : 357-360, 1967.

10.Hurseh C.J., et al, Some characteristic of nocturnal penile tumescence in early middle-aged males., Comprehensive psychiatry, Vol 13, No 6, 539-548, 1972.

11.Johnson J., Sexual impotence and the limbic system. Brit. J. Psychiat, 111, 300 - 303, 1965.

12.Karacan 1, Some characteristics of nocturnal penile tumescence in elderiy males, Journal of Gerontology vol 27, No 1, 39-45, 1972,

13.Karacan 1. et al. Establishment and implemettation of standardized sleep laboratory data collection and scoring procedures,, Psychophysiology vol 15, no 2, 173-179, 1978.

14.Karacan 1. et al, The ontogeny of nocturnal penile tumescence. Waking and sleeping 1 : 27-44, 1976.

15.Karacan 1, Advances in the diagnosis of erectile impotence., Medical Aspecis ol human sexuality, May, 1978.

16.Karacan 1. Clinical value of nocturnal erection in the prognosis and diagnosis of impotence., Medical Aspects of human sexuality, April, 1970.

17.Karacan 1., Moore C.A., Objective methods of differentiation between organic and psychogenic impotence., Male Reproductive Dysfunction. Marcel Dekker Inc., New York and Basel, pp : 545-562, 1986.

18.Karacan 1., Nocturnal penile tumescence as a biologic marker in assessing erectile dysfunction., The Journal of the academy of psychosomatic medicine vol 23, No 4, 1982.

19.Karacan 1. et al, Some characteristics of nocturnal penile tumescence in young adults., Arch Gen Psychiat. Vol 26 351-356, 1972.

20.Klüver H., and Bucy P.C,, Preliminary analysis of functions of the temporal lobes in monkeys., Archives of Neurology and Psychiatry, Vol 42, No 6, 979-1000, 1939.

21.MacLean P.D., and Ploog D.W. Cerebral representation of penile erection., Journal of Neurophysiology Vol 25, 29-55, 1962.

22.Nagler H.M, et al., The role of fenular penile brachial indices in the assessment of penile vasculature. American Urological Association, 77th Annual Meeting, 1982.

23.Shukla G.D,, et al., Sexual disturbances in temporal lobe epilepsy : A controlled study., Brit. J. Psychiat. 134 : 288-292, 1979.

24.Spark R.F,, et al. Hypogonadism, hyperprolactinaemla, and temporal lobe epilepsy in hyposexual men., The Lancet, February 25, 413-417, 1984.

25.Williams R.L., Karacan 1., The role of the sleep laboratory in diagnosis and treatment of impotence. Sleep Disorders diagnosis and treatment, John Wiley& Sons Pub., New York, Toronto, Brisbane, pp : 353-401, 1978.