Ankara Üniversitesi Tıp Fakültesi Mecmuası

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Ankara University

Pathology

Patoloji

Çocukluk Çağı Non-Hodgin Lenfomaları

Childhood Non-Hodgkin's Lymphomas

Sertçelik

Ayşe

AÜ. Tıp Fak. Patoloji Anabilim Dalı

09 30 1986

39 3 233 242 07 01 1986 09 30 1986

1947

Ankara Üniversitesi Tıp Fakültesi Mecmuası

Makalemizde, 1189 çocukluk çağı tümörleri içinde yer alan 158 non-Hodgkin lenfoma olguları sunulmuştur. Bu non-Hodgkin lenfoma olguları Kiel Klasifikasyonuna göre değerlendirilmiştir. 128 non-Hodgkin lenfoma olgumuz lenfoblastik tip olup bunun % 34.4 ü Burkitt tiptir. Burkitt tip lenfoma olgularının % 682 si batında yerleşim göstermiştir, buna karşın non-Burkitt olanlarda bu oran % 25 dir.Araştırmamızda diğer çocukluk çağı malign tümörleri arasında çocukluk çağı lenfomalarınm ilk sırayı aldığı belirlenmiştir.

One hundred and fifty eight cases of non-Hodgin's lymphoma among 1189 childhood malignant tumors were present . These non hodgin's lymphoma cases were reviewed according Kiel's classification and rediagnosed. One hundred twenty eight cases of non-Hodgkin's lymphoma were lymphoblastic type whose 34.4 % was Burkitt type, and 68.2 % of Burkitt's lymphoma was located in the abdomen, although in non, Burkitt's lymphoma 25 % of cases showed abdominal involvement. Our results demonstrated that the childhood lymphoma comes first among the other malignant tumors.

kötü huylu lenfoblastik Kiels Non-Hodgkin

malignant lymphoblastic Kiels Non-Hodgkin's

I. Birch JM, Marsden MB, Swindell R : Incidence of malignant disease in child hood. A 24 year review of Manchester children's tumor regisitry data. Br J Cancer. 42 : 215, 1980.

2. Cutler SJ, Young JL : Third national cancer survey : incidence data nat Cancer Inst Monogra 41 : 100, 1975.

3. Çavdar A, Gözdasoälu S, Arcasoy A et al : High frequency of Hodgkin's disease in Turkish children. New Istanbul Contr Clin Sc 11 : 31, 1974.

4. Çevik N, Büyükpamukçu M, Tekmalp G et al : 1972-1983 Ylllarl araslnda H.Ü. Çocuk Hastanesinde görülen çocukluk çažl malign tümörleri. Ill. Ulusal Pediatrik Tümörler Kongresi. 315, 1984.

5. Hausner RJ, Rosas-Uribe A, Wickstrum DA, et al. : Non-Hodgkin's lymphoma in the first two decades of life: a pathological study of 30 cases. Cancer 40 : 1533, 1977.

6. Kjeldsberg C, Wilson J, Berard CW : Non-Hodgkin's lymphoma in children Hum Pathol. 14 612, 1983.

Murphy SB : Classification, taging and end-results of treatment of childhood non-Hodgkin's lymphomas : Dissimilarities from lymphomas in adults. Semin Oncol 7: 332, 1980.

8. Pastore G, Magnani C, Zanetti R, Terracini B : Incidence of cancer in children in the province Torino (Itay) 1967 1978. Eur J Cancer Oncol. 17 (12) : 254, 1981

9. Sabbah RS : Childhood cancer in Saudi Arabia. Current problems and suggest solution. The King Faisal Specialist Hosp Med J 2 (4) : 272, 1982.

10. Williams AO : Tumors of childhood in Ibadan, Nigeria. Cancer. 36 : 370, 1975.

11. Wilson JF, Jenkin RDT, Anderson JR et al : Studies on the pathology of nonHodgkin's lymphoma of childhood. Cancer' 53 : 1695, 1984.

12. Young JL, Miller RW : Incidence of malignant tumors in U.S. children. J Pediatr 86 : 254, 1975.