Ankara Üniversitesi Tıp Fakültesi Mecmuası

0365-8104 1307-5608

Ankara University

Nuclear Medicine

Nükleer Tıp

Şizofreni ve Depresyonda

«SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY» (SPECT) AND «POSTTRON EMISSION TOMOGRAPHY» IN SCHIZOPHRENIA AND DEPRESSION

Karayalçın

Binnur

AKDENİZ ÜNİVERSİTESİ, TIP FAKÜLTESİ

09 30 1992

45 3 529 540 08 10 1992 09 10 1992

1947

Ankara Üniversitesi Tıp Fakültesi Mecmuası

Psikiyatrik hastalıkların değerlendirilmesinde, PET ile yapılan önemli katkılardan sonra, serebral SPECT çalışmaları da çok umut verici görünmektedir. Özellikle son yıllarda, SPECT teknolojisindeki gelişmelere ve yeni radyo-farmasötiklerin bulunmasına paralel olarak bu konuda yapılan çalışmalar hızla artmaktadır. Hernekadar elde edilen sonuçlar henüz mental hastalıkların tanısında ve sınıflandırı!- masında patognomonik olmasada, özellikle şizofreninin bazı formları ile depresyonun değerlendirilmesine önemli katkıları olmuştur. Bir diger önemli husus, hastaya uygun tedavinin seçiminde ve tedaviye alınan yanıtın değerlendirilmesinde, halen kabul edilmiş olan klinik prametreler yanında önemli objektif kriter olacağıdır. Ayrıca kullanılan radyofarmasötiklerin geliştirilmesi, özellikle reseptör görüntülenmesine yönelik çalışmalar, bazı psikiyatrik hastalıkların etiopatogenezini aydınlatmada yardımcı olacaktır.

After major contribution of PET studies to the assessment of schizophrenia and affective disorders, SPECT imaging also seems to be promising. Especially recent developments in SPECT technology and new radiopharmaceuticals have contributed significant advanceş in the evaluation of mental disorders. Although the results are not yet patognomonic for diagnosing and subtyping mental disorders, some improvements were obtained in some forms of schizophrenia and depression. In addition, SPECT receptor site imaging will be guite useful to elucidate the underilying mechanisms responsible for some phychiatric disease.

Şizofreni Depresyon SPECT PET.

Schizophrenia Depression SPECT PET.

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