Ankara Üniversitesi Tıp Fakültesi Mecmuası 0365-8104 1307-5608 Ankara University Gastroenterology Surgery Gastroenterology and Hepatology Gastroenteroloji Cerrahisi Gastroenteroloji ve Hepatoloji Türkiye'de Kronik Hepatitin Özellikleri ve Etyolojik Faktörler Characteristics And Etiological Factors Of Chronic Hepatitis In Turkey Paykoç Zafer ANKARA ÜNİVERSİTESİ, ANKARA TIP FAKÜLTESİ 09 30 1976 29 3 613 622 07 29 1976 09 29 1976 Copyright © 1947, Ankara Üniversitesi Tıp Fakültesi Mecmuası 1947 Ankara Üniversitesi Tıp Fakültesi Mecmuası

A. Ü. Tıp Fakültesi Gastroenteroloji Kliniğinde takip edilen kronik hepatit vak'a gurubu incelenerek Türkiye'de kronik hepatit etyolojisine yaklaşımda bulunulmuştur.40 Kronik hepatit vak'asında yapılan klinik, serolojik ve histopatolojik inceleme ile 9 kronik persistant hepatit, kronik aktiv hepatit örneği saptanmıştır. Vak'alarımızın tümünde HB ag positivliği % 47 bulundu bu oran kronik aktiv hepatitde % 51.0 kronik persistant hepa-UGUR KANDÌLCÌ — ÖZDEN UZUNALÏMOGLU ZAFER PAYKOÇtitde % 33.3 dür. Kronik aktiv hepatit vak'alarm yalnu 3 tanesi sistemik belirtileri ile Lupoid hepatit tipindedir. Bu bulgular ile memleketimizde Kronik hepatit vak'alarmm hemen yarlS1 HB ag (+) , sinsi seyirli sistemik belirtileri bulunmwan ve laboratuvarda orta derecede transmmaz) globilin yüksekliži ile karakterize vak'alar oldužunu göstermektedir. Etyolojide sorumlu ilâçlar, alkol, otoimmun mekanizma ile olusan kronik aktiv hepatit örnežinin memleketimizde oldukça nadir oldugu kamslndasnz.

40 patients with chronic hepatitis were studied clinically, and histopatologically. These cases were diided into two groups. 9 of these cases proved to be persistant hepatitis, 31 of these to be chronic active hepatitis.In 47 % of he chronic hepatitis cases HB Ag was positiv. This relation was found 51 percent in the patients with chronic active hepatitis and 33 percent in chronic persistant hepatitis only 3 of all the chronic active hepatitis cases were lupold„ he patitis type.The results suggest thet in our cauntry aetiologically alc Alcohol hol, drugs, or autoimmun mechanisms is quite rare in pathogenesis of chronic hepatitis.

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