Ankara Üniversitesi Tıp Fakültesi Mecmuası

0365-8104 1307-5608

Ankara University

Pediatric Nephrology

Çocuk Nefrolojisi

Hemolitik Üremik Sandrom

Hemolytic Uremic Syndrome

Tümer

Necmiye

ANKARA ÜNİVERSİRESİ TIP FAKÜLTESİ PEDİATRİ ANABİLİM DALI

09 30 1976

29 3 745 759 07 01 1976 09 30 1976

1947

Ankara Üniversitesi Tıp Fakültesi Mecmuası

Bu makalede hemolitik üremik sendrom'un etyoloji, patogenez, patoloji, klinik, laboratuvar bulguları ve tedavisi literatür gözden geçirilerek detaylı incelenmiştir.

This article reviewes the literature in detial on the hemolytic uremic syndrome. Etiology, pathogenesis, clinicopathology, laboratory findings and treatment are diccussed.

Mikroanjiopatik Hemolitik Anemi Akut Böbrek Yetmezliği trombositopeni

Microangiopathic Hemolytic Anemia Acute Renal Failure Thrombocytopenia

1 — Abildgaard, F.C: Medical Progress; Recognition and Treatment of IMmtravascular Coaguletion, J, Pediatr. 74:163, 1969. i

2 - Bergstein, J. M., Edson, J.R., Michael, AF. Fibrinolytic Treatment of the Hemolytic Üremic Syndrome. Lancet 1; 448, 1972.

3 — Boichis, H., Winterborn, H.M. Acute Renal Failure in Childhood, Pediatr. Ann. April: 58, 1974.

4 — Cambell, S., Carre, 1J.: Fatal Hemolytic Uremic Syndrome and Idıopathic Hiperlipemia in Monozygotic Twins. Arch. Dis. Childh. 40:654, 1965.

5 — Geyner, E, Bouvier, C., Spaet, T.H.. Vascular Lesions: Possible Pathogenic Basis of the Generalized Schwertzman. Science 170: 896, 1970.

6 — Gervais, M., Richardson,.J.B., Chin, J., Drummond, K.N.: Immunofluorescent and histologic Findings in the Hemolytic Uremic Syndrome. Pediatrics 47:352, 1971. i

7 — Gillehrist, G.S., Lieberman, E, Ekert, H., Fine, R.N., Grushkin, G. Heparin Therapy in the Hemolytic Üremic Syndrome. Lancet 1:1123, 1969.

8— Kaplan, B.S., Katz, J., Krawitz, 5. Lurie, A: An Analysis of the Resultsof Therapy in 67 Cases of the Hemolytic Uremic Syndrome. J. Pediatr. 78:420, 1971.

8 — Kaplan, B.S,, Katz, J., Krawitz, S., Sacks, V.P.: Platelet, Erythrocyte and Fibrinogen Kinetic in the Hemolytic Üremic Syndrome of Infancy. - J. Pediatr. 83: 739, 1973

10 — Lieberman, E.: Oo Medical. Progress; Hemolytic Uremic Syndrome. J. Pediatr. 80:1, 1972 .

11 — Lieberman, E., Heuser, E., Donnel, N.G,, Landing, B.H., Hammond, G.D.: - Hemelytic Uremic Syndrome, Clinical and Pathological.Considerations. New Eng. J. Med. 275: 227, 1966.

12 — Mettler, N.E. Isolation ofa Microtatobiote İrom Petients with Hemolytic Uremic Syndrome and Thrombotic Thrombocytopenic Purpura and İrom Mites in the United States. New Eng. J. Med. 281: 1023, 1969.

13 — Metz, J. Observations on the Mechanism of the Haematological Changes in'the Hemolytic Üremic Syndrome of Mmfancy. Brith. J. Haematology. 23 Suppl). 58: 53, 1972.

14 — Mormes, L., Kleyneu, F., Van Munster, P., Schretten, E., Bonnerman, A: Coagulation Studies and Streptokinase Therapy in the Hemolytic Uremic Syndrome. Helv. Pediatr. Acta, 27:45, 1972.

15 — Nash, A.M. İmmunology of Glomerular Diseases. Pediatr. Ann. April 9, 1974.

16 — Ray; G.C, Portman, N.J,, Stamm, J.S., Hickman, O. R.: Hemolytic Uremic Syndrome and Myocarditis. Am, J. Dis. Child. 22:418, 1971.

17 — Royer, P., Habib, R., Mathion, H., Broyer, M. Pediatris Nephrology, W.B. Saunders Co. Phila., London, 1974. . 18 — Rubin, MI, Barratt, T.M. Pediatric Nephrology. Williams gnd Wilkins Co. Baltimore, 1975.

19 — Strauss, M.B. Welt, L.G.: Diseases of the Kidney. Sec. Edit. Little, Brown and Co,, Boston, 1971. i

20 — Uttley, W.S.: Serum Levels of Fibrin/Fibrinogen Degragtion Products İn the Hemolytic Uremic Syndrome. Arch. Dis. Childh. 45: 587, 1970.

21 — Vaughan, V.C., McKay, R.J., Nelson, W.E. Textbook of Pediatrics, W.B. Saunders Co. Phila., London, Toronto, 1975.

22 — Wieringen, P.M.V., Monnes, LA., Schretlen, E.D.A.: Hemolytic Uremic Syndrome: Epidemiyological and Clinical Study. Arch. Dis Childh. 49:432, 1974.

23 — Wintrobe, MM.