<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.4 20241031//EN"
        "https://jats.nlm.nih.gov/publishing/1.4/JATS-journalpublishing1-4.dtd">
<article  article-type="research-article"        dtd-version="1.4">
            <front>

                <journal-meta>
                                    <journal-id></journal-id>
            <journal-title-group>
                                                                                    <journal-title>Ankara Üniversitesi Tıp Fakültesi Mecmuası</journal-title>
            </journal-title-group>
                            <issn pub-type="ppub">0365-8104</issn>
                                        <issn pub-type="epub">1307-5608</issn>
                                                                                            <publisher>
                    <publisher-name>Ankara University</publisher-name>
                </publisher>
                    </journal-meta>
                <article-meta>
                                        <article-id/>
                                                                <article-categories>
                                            <subj-group  xml:lang="en">
                                                            <subject>Anaesthesiology</subject>
                                                    </subj-group>
                                            <subj-group  xml:lang="tr">
                                                            <subject>Anesteziyoloji</subject>
                                                    </subj-group>
                                    </article-categories>
                                                                                                                                                        <title-group>
                                                                                                                        <article-title>Ağrı Tedavisinde Hipotermik Subaraknoid İrrigasyon</article-title>
                                                                                                                                                                                                <trans-title-group xml:lang="en">
                                    <trans-title>Hypothermic Subarachnoid Irrigation for Pain Management</trans-title>
                                </trans-title-group>
                                                                                                    </title-group>
            
                                                    <contrib-group content-type="authors">
                                                                        <contrib contrib-type="author">
                                                                <name>
                                    <surname>Akkartal</surname>
                                    <given-names>Birsen</given-names>
                                </name>
                                                                    <aff>ANKARA UNIVERSITY, ANKARA FACULTY OF MEDICINE</aff>
                                                            </contrib>
                                                                                </contrib-group>
                        
                                        <pub-date pub-type="pub" iso-8601-date="19721231">
                    <day>12</day>
                    <month>31</month>
                    <year>1972</year>
                </pub-date>
                                        <volume>25</volume>
                                        <issue>6</issue>
                                        <fpage>1345</fpage>
                                        <lpage>1355</lpage>
                        
                        <history>
                                    <date date-type="received" iso-8601-date="19721010">
                        <day>10</day>
                        <month>10</month>
                        <year>1972</year>
                    </date>
                                                    <date date-type="accepted" iso-8601-date="19721227">
                        <day>12</day>
                        <month>27</month>
                        <year>1972</year>
                    </date>
                            </history>
                                        <permissions>
                    <copyright-statement>Copyright © 1947, Ankara Üniversitesi Tıp Fakültesi Mecmuası</copyright-statement>
                    <copyright-year>1947</copyright-year>
                    <copyright-holder>Ankara Üniversitesi Tıp Fakültesi Mecmuası</copyright-holder>
                </permissions>
            
                                                                                                <abstract><p>Normal yollarla giderilemeyen ağrıların ortadan . kaldırılması için 11 hastada spinal iğne ile lomber bölgeden girilerek serebrospinal sıvı boşaltılmış ve yerine alınan sıvı kadar soğuk serum fizyolojik verilmiştir.11 hastanın 6 sında olumlu sonuç alınamamış, geri kalan 5 hastada ise değişik sürelerle devam eder bir analjezi sağlanmıştır.</p></abstract>
                                                                                                                                    <trans-abstract xml:lang="en">
                            <p>For persistent pain, 11 patients underwent spinal puncture from the lumbar region and were given some cold, physiological serum physiological after the cerebrospinal fluid was aspirated.The result was negative in six patients. Analgesia was provided for the remaining 5 patients for different periods.</p></trans-abstract>
                                                            
            
                                                            <kwd-group>
                                                    <kwd>AĞRI TEDAVİSİ</kwd>
                                                    <kwd>  ANESTEZİ</kwd>
                                                    <kwd>  CERRAHİ</kwd>
                                            </kwd-group>
                                                        
                                                                            <kwd-group xml:lang="en">
                                                    <kwd>PAIN TREARMENT</kwd>
                                                    <kwd>  ANAESTHESIOLOGY</kwd>
                                                    <kwd>  SURGERY</kwd>
                                            </kwd-group>
                                                                                                        <funding-group specific-use="FundRef">
                    <award-group>
                                                    <funding-source>
                                <named-content content-type="funder_name">Ankara University Faculty of Medicine</named-content>
                            </funding-source>
                                                                    </award-group>
                </funding-group>
                                </article-meta>
    </front>
    <back>
                            <ref-list>
                                    <ref id="ref1">
                        <label>1</label>
                        <mixed-citation publication-type="journal">1	— BATTISTA, F. A.: Subarachnoid cold Saline Wash for Pain relief.  Arch. surg. vol 103, Dec. 1971</mixed-citation>
                    </ref>
                                    <ref id="ref2">
                        <label>2</label>
                        <mixed-citation publication-type="journal">2	— BUNGE R. P., SETTLAGE P. H.: Neurological lesion in cats fallowing cerebrospinal fluid maniqulation, J. Neuropath. Exp. Neurol. 16 : 471 491, 1957</mixed-citation>
                    </ref>
                                    <ref id="ref3">
                        <label>3</label>
                        <mixed-citation publication-type="journal">3	COLLINS J. R., JURAS B. P., VON HOUTEN R. 1., ET AL : Intrathecal cold Saline Solution A new approach to pain (Evaluation) Anesth. Analg. 48 : 816 823, 1969</mixed-citation>
                    </ref>
                                    <ref id="ref4">
                        <label>4</label>
                        <mixed-citation publication-type="journal">4	DENNY - BROWN D, ADAMS R. D, BRENNER, C, ET AL : The pathology of injury to nerve induced by cold. J. neuropath. Exp. Neurol.  4 : 305 323, 1945</mixed-citation>
                    </ref>
                                    <ref id="ref5">
                        <label>5</label>
                        <mixed-citation publication-type="journal">5	— FAY T, MC GRAV\&#039;.V A : Pain relief by •local and generalized r  ration. Dis. Nerv. syst. 1. : 209 - 211, 1940</mixed-citation>
                    </ref>
                                    <ref id="ref6">
                        <label>6</label>
                        <mixed-citation publication-type="journal">6	— FAY T, SIMITH G. W. : Obsercation on reflex response during prolonged periods of human refrigeration. Arch. Neural. Pasychiat. 45 : 215 - 222, 1941</mixed-citation>
                    </ref>
                                    <ref id="ref7">
                        <label>7</label>
                        <mixed-citation publication-type="journal">7	— HITCHCOCK E. : Hypothermic Subarachnoid Irrigation for Intractable pain Lancet 1 : 1133 - 1135, 1967</mixed-citation>
                    </ref>
                                    <ref id="ref8">
                        <label>8</label>
                        <mixed-citation publication-type="journal">8	—m HITCHCOCK, : Osmolytic Neurolysis for intractable facial paLn Lancet 1: 434 - 436, 1969</mixed-citation>
                    </ref>
                                    <ref id="ref9">
                        <label>9</label>
                        <mixed-citation publication-type="journal">9	— KIMOTO S, SUGIÐ S, ASANO K : open heart surgery under direct   vision with aid of brain cooling by irrigation, Surgery 39 : 592 - 603, 1965</mixed-citation>
                    </ref>
                                    <ref id="ref10">
                        <label>10</label>
                        <mixed-citation publication-type="journal">10 LUNDBERG Potassium and the differential thermosensivity of membrane potential : Spike and negative after potential in mamalian A and C fibers. Acta Physiol. Scand. 15 (suppl 50) : 1 - 67, 1948</mixed-citation>
                    </ref>
                                    <ref id="ref11">
                        <label>11</label>
                        <mixed-citation publication-type="journal">11	MAHER, R. M. Lancet 1955, 1. 18</mixed-citation>
                    </ref>
                                    <ref id="ref12">
                        <label>12</label>
                        <mixed-citation publication-type="journal">12	— MATHÐUS G. J., PACE FLORIDIA A.: Intrathecal cold saline for the relief of intractable pain. Canad, Med. Assoc. J. 103 • 1143 1146, 1970</mixed-citation>
                    </ref>
                                    <ref id="ref13">
                        <label>13</label>
                        <mixed-citation publication-type="journal">13	MC KEAN MC, HÏTCHCOCK : Electrocardiographic changes after intratfecal hypertonic saline solution. Lancet 2 • 1083 - 1084, 1968</mixed-citation>
                    </ref>
                                    <ref id="ref14">
                        <label>14</label>
                        <mixed-citation publication-type="journal">14	— MULLAN S, HARPER pv, Hekmatphanh J, et al. : Percutaneous in. terruption of spinal pain tracts by means of a strontwm needle, J. Neurosurg. 20 • 931 - 939, 1963</mixed-citation>
                    </ref>
                                    <ref id="ref15">
                        <label>15</label>
                        <mixed-citation publication-type="journal">15	Negrin J. Excepta med. int. Congr. Ser. 1966 : 110</mixed-citation>
                    </ref>
                                    <ref id="ref16">
                        <label>16</label>
                        <mixed-citation publication-type="journal">16	NEGRÏN J. : Selective hypothermia in neurosurgery. Newyork J. Med.61 • 2951 2954, 1961</mixed-citation>
                    </ref>
                                    <ref id="ref17">
                        <label>17</label>
                        <mixed-citation publication-type="journal">17	O. HIGGINS J. W,   A., Clapp H. : Possible complication of hypothermic saline subarachnoid injection. Lancet : Marc 1970, pp, 567</mixed-citation>
                    </ref>
                                    <ref id="ref18">
                        <label>18</label>
                        <mixed-citation publication-type="journal">18	— Patterson R H Jr., Ray R S. : Profound hypottermia for intracranial surg. Ann. Surg. Ann. Surg. 156 377 - 393, 1962</mixed-citation>
                    </ref>
                                    <ref id="ref19">
                        <label>19</label>
                        <mixed-citation publication-type="journal">19	ROSOMOFF HL, CARROLL F, BROWN J. ET AL.: Percutaneous radioprequency cervical cordotomy techniaue. J. Neurosurg. 23 • 630  644, 1965</mixed-citation>
                    </ref>
                                    <ref id="ref20">
                        <label>20</label>
                        <mixed-citation publication-type="journal">20	SHAPÏRO H. : Osmotic properties of frog nerve comp, Biochem. Phy siol. 19 : 225 239, 1966</mixed-citation>
                    </ref>
                                    <ref id="ref21">
                        <label>21</label>
                        <mixed-citation publication-type="journal">21	STEVENSON GC., COLLtNS W F, RAUDT CT, ET AL : Effect of in. duced hypothermia on subcortical evoked potentials In the cat Amer. J. Physlol. 194 : 423 - 426, 1958</mixed-citation>
                    </ref>
                                    <ref id="ref22">
                        <label>22</label>
                        <mixed-citation publication-type="journal">22	THOMPSON G E. : Pulmoner edema complicating intrathecal hypertonic saline infection for intractable pain. Anesthesiology 35 : 425, 1971</mixed-citation>
                    </ref>
                                    <ref id="ref23">
                        <label>23</label>
                        <mixed-citation publication-type="journal">23	TSUBOKAWA T, : The effects of intratecal frozen saline perfusion on the thalamic responses and dorsal root potentials rasponding to sciatic nerve stimülation and noX10us stimuli. Bram Nerve 21 • 81 - 88, 1969 24 VON EULER C.: Acta physiol. Scand 1947, 14 supi 45</mixed-citation>
                    </ref>
                                    <ref id="ref24">
                        <label>24</label>
                        <mixed-citation publication-type="journal">25	WILKINSON H.A., MARK v.H., White J. C. J. Chronic Dis. 1964, 11 •1055</mixed-citation>
                    </ref>
                                    <ref id="ref25">
                        <label>25</label>
                        <mixed-citation publication-type="journal">26	WtLSON . CB.: . What&#039;s new In surgery.- Neurologic surgery, Surg. Gynec. Obstet.132 • 225 - 228, 1971</mixed-citation>
                    </ref>
                            </ref-list>
                    </back>
    </article>
