Ankara Üniversitesi Tıp Fakültesi Mecmuası 0365-8104 1307-5608 Ankara University Pediatric Hematology and Oncology Çocuk Hematolojisi ve Onkolojisi Hereditary Elliptocytosis Herediter Elliptositosis Arcasoy Ayten ANKARA ÜNİVERSİRESİ TIP FAKÜLTESİ, PEDİATRİ POLİKLİNİĞİ 12 31 1972 25 6 1373 1381 11 01 1972 12 30 1972 Copyright © 1947, Ankara Üniversitesi Tıp Fakültesi Mecmuası 1947 Ankara Üniversitesi Tıp Fakültesi Mecmuası

Hereditary Elliptocytosis Hereditary elliptocytosis is a very rare disorder, for this reason three patients with hereditary elliptocytosis are presented. Osmotic fragility increased in one case and her mother. Other hematological findings such as Hb A2, Hb F, G6PD, serum iron and iron binding capacyty were normal.

Herediter elliptositosisli üç vak'a anomalinin nadir oluşu nedeniyle takdim edildi.Hastalarda ve inceleyebildiğimiz aile fertlerinde yapılan Hb A2, G6PD serum demiri ve total demir bağlama kapasiteleri normal bulundu. Vak'alardan birinde ve annesinde osmotik frajilite artmıştı.

 Herediter Elliptositosis osmotik frajilite nadir Hereditary Elliptocytosis osmotic fragility rare AÜ. Tıp Fakültesi Çocuk HastalıkIarı ve Sağlığı Kliniği 1 AKSOY, M. AND ERDEM, Ş. : Combination of hereditary elliptocytosis and heterozygous beta - thalassemia. A family study. J. Med. Genet. 5 : 298, 1968. 2 AKSOY, M., ERDENİZ, Ş., DİNÇOL, E: Türkiye'de herediter elliptositoz problemi. VII. Türk Hematoloji Kongresi, 1972, Hematoloji Ill, Kâglt ve 'Baslm isleri P: 256. 3 ANGELOPOULOS, B. AND CARALİS, D: Hereditary elliptocytosis associated with heterozygous beta-thalassemia. A study in a Greek family. Ann. Paediat. 204 : 336, 1965. 4 BAEHNER. R. L.. GiLCHRïST, G.S., AND ANDERSON. E: Hereditary elliptocytosis and primary renal tubular acidosis in a single family. Amer. J. Dis. Child. 115 • 414, 1968. 5 MAUER, A. M. : Pediatric hematólogy. p. : 156, McGraw-Hill Book Com., 1969. 6 NELSON, VAUGHAN, MCKAY : Hereditary elliptocytosis. Textbook of periatrics. 9. Ed. W. B. Saunders Com., 1969. 7 PEARSON, H. A. : The genetic basis of hereditary elliptocytosis with hemolysis. Blood 32 : 972, 1968. 8 — PERİLLİE, P. E., AND CHERNOFF, A.l.: Heterozygous beta-thalassemia in association with hereditary elliptocytosis. A family study. Blood 25 : 494, 1965. 9 — PRYOR, D. S., AND PïTNEY, W. R.: Hereditary elliptocytosis. A report of two families from New Guinee, Brit. J. Hemat. 19 : 126, 1967. 10 RNGELHANN, B, KONOTEY-AHULU, F. 1. D, LEHMANN, H., ND LORKİN, P. A.: A Ghananian adult. Homozygous for hereditary persistence of foetal hemoglobin and heterozygous for elliptocytosis. Acta Haemat. 43 : 100, 1970. Il Weiss, H, J. : Hereditary elliptocytosis with hemolytic anemia. Amer. J. Med. 35 : 455, 1963. 12 WïNTROBE, M. M.: Clinical hematology. 6. Ed. Lea and Fabiger, Philadelphia, 1967.