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<article  article-type="research-article"        dtd-version="1.4">
            <front>

                <journal-meta>
                                    <journal-id></journal-id>
            <journal-title-group>
                                                                                    <journal-title>Ankara Üniversitesi Tıp Fakültesi Mecmuası</journal-title>
            </journal-title-group>
                            <issn pub-type="ppub">0365-8104</issn>
                                        <issn pub-type="epub">1307-5608</issn>
                                                                                            <publisher>
                    <publisher-name>Ankara University</publisher-name>
                </publisher>
                    </journal-meta>
                <article-meta>
                                        <article-id/>
                                                                <article-categories>
                                            <subj-group  xml:lang="en">
                                                            <subject>Nuclear Medicine</subject>
                                                    </subj-group>
                                            <subj-group  xml:lang="tr">
                                                            <subject>Nükleer Tıp</subject>
                                                    </subj-group>
                                    </article-categories>
                                                                                                                                                        <title-group>
                                                                                                                        <trans-title-group xml:lang="en">
                                    <trans-title>INVITRO (THYROID HORMONE BINDING CAPACITY INDEX) AND T4 (TOTAL SERUM THYROXINE RATIO) TESTS FOR THE EXAMINATION OF THYROID FUNCTION</trans-title>
                                </trans-title-group>
                                                                                                                                                                                                <article-title>Tiroid Fonksiyonunun İncelenmesinde İnvitro T3 (Tiroid Hormonu Bağlama Kapasitesi İndeksi) ve T4 (Total Serum Thyroxine Oranı) Testleri</article-title>
                                                                                                    </title-group>
            
                                                    <contrib-group content-type="authors">
                                                                        <contrib contrib-type="author">
                                                                <name>
                                    <surname>Renda</surname>
                                    <given-names>Fevzi</given-names>
                                </name>
                                                                    <aff>ANKARA ÜNİVERSİTESİ, ANKARA TIP FAKÜLTESİ</aff>
                                                            </contrib>
                                                                                </contrib-group>
                        
                                        <pub-date pub-type="pub" iso-8601-date="19750630">
                    <day>06</day>
                    <month>30</month>
                    <year>1975</year>
                </pub-date>
                                        <volume>28</volume>
                                        <issue>1-2</issue>
                                        <fpage>575</fpage>
                                        <lpage>588</lpage>
                        
                        <history>
                                    <date date-type="received" iso-8601-date="19750101">
                        <day>01</day>
                        <month>01</month>
                        <year>1975</year>
                    </date>
                                                    <date date-type="accepted" iso-8601-date="19750603">
                        <day>06</day>
                        <month>03</month>
                        <year>1975</year>
                    </date>
                            </history>
                                        <permissions>
                    <copyright-statement>Copyright © 1947, Ankara Üniversitesi Tıp Fakültesi Mecmuası</copyright-statement>
                    <copyright-year>1947</copyright-year>
                    <copyright-holder>Ankara Üniversitesi Tıp Fakültesi Mecmuası</copyright-holder>
                </permissions>
            
                                                                                                <trans-abstract xml:lang="en">
                            <p>In this article, the results and method obtained with the total serum thyroxine ratio and thyroid hormone initiation capacity index for more than 315 cases are weighed§lldl. Thyroid disease 1 These invitro tests, performed without any radiation exposure, can also be used safely in children and pregnant women. The thyroid hormone binding capacity index, which gives a value between 0.85 - 1.20 in normal SAH1S, gives values above 1.20 in cases of hypothyroidism and below 0.85 in hyperthyroidism. The ratio of total serum thyroxine was normally found to be 5 - 14 nanograms below 5 nanogrammes in hypothyroidism and above 14 nanogrammes in hyperthyroidism. There are some thyroid gland DL events that cause both tests to give incorrect results. These reasons make the comparative evaluation more meaningful by performing both tests on the client.</p></trans-abstract>
                                                                                                                                    <abstract><p>Bu makalede 315&#039;ten fazla olgu için total serum tiroksin oranı ve tiroid hormon başlangıç kapasite indeksi ile elde edilen sonuçlar ve yöntem tartılmıştır. Tiroid hastalığı 1 Radyasyona maruz kalmadan yapılan bu ınvitro testleri çocuklarda ve hamile kadınlarda da güvenle kullanılabilir. Normal sah1&#039;lerde 0,85 - 1,20 arasında değer veren tiroid hormon bağlama kapasitesi indeksi hipotiroidizm vakalarında 1,20&#039;nin üzerinde, hipertiroidizmde 0,85&#039;in altında değerler verir. Total serum tiroksin oranı normalde hipotiroidizmde 5 nanogramın 5 - 14 nanogram altında ve hipertiroidizmde 14 nanogramın üzerinde bulundu. Her iki testin de yanlış sonuç vermesine neden olan bazı tiroid bezi DL olayları vardır. Bu nedenler, her iki testi de müşteri üzerinde gerçekleştirerek karşılaştırmalı değerlendirmeyi daha anlamlı hale getirir.</p></abstract>
                                                            
            
                                                                                        <kwd-group>
                                                    <kwd>tiroid</kwd>
                                                    <kwd>  T4</kwd>
                                                    <kwd>  HORMONLAR</kwd>
                                            </kwd-group>
                            
                                                <kwd-group xml:lang="en">
                                                    <kwd>THYROID</kwd>
                                                    <kwd>  T4</kwd>
                                                    <kwd>  HORMONE</kwd>
                                            </kwd-group>
                                                                                                                                    <funding-group specific-use="FundRef">
                    <award-group>
                                                    <funding-source>
                                <named-content content-type="funder_name">ankara üniversitesi tıp fakültesi</named-content>
                            </funding-source>
                                                                    </award-group>
                </funding-group>
                                </article-meta>
    </front>
    <back>
                            <ref-list>
                                    <ref id="ref1">
                        <label>1</label>
                        <mixed-citation publication-type="journal">1	Freeman, L. M., Blaüfox, M. D. : Test of thyroid fonction. Physicians&#039; Desk Reference for Radiology and Nuclear Medicine. 1971.</mixed-citation>
                    </ref>
                                    <ref id="ref2">
                        <label>2</label>
                        <mixed-citation publication-type="journal">2	Blahd, W. H. : Nuclear Medicine. McGrow -Hill B. Com. New York. Second Ed. 208, 1971.</mixed-citation>
                    </ref>
                                    <ref id="ref3">
                        <label>3</label>
                        <mixed-citation publication-type="journal">3	Wagner, H. N. : Principles of Nuclear Medicine. Saunders Com.  320, 1968.</mixed-citation>
                    </ref>
                                    <ref id="ref4">
                        <label>4</label>
                        <mixed-citation publication-type="journal">4	Nava, M., De Groot, L. J. : Resine uptake of I- 131 - labeled Tri - iodothyronine as a test of thyroid function. New Engl. J. Med. 266 : 1307, 1963.</mixed-citation>
                    </ref>
                                    <ref id="ref5">
                        <label>5</label>
                        <mixed-citation publication-type="journal">5	Sodee, D. B. : Clinical usefulness of the I - 131 - triidothyronine erytrocyte uptake test. JA-MA, 185 : 100, 1963.</mixed-citation>
                    </ref>
                                    <ref id="ref6">
                        <label>6</label>
                        <mixed-citation publication-type="journal">6	— Murphy, B. P., Pattee, C. J. : Determination of thyroxine utilizing the property of protein binding. J. Clin. Endoc. And Metob. 24 : 187, 1964.</mixed-citation>
                    </ref>
                                    <ref id="ref7">
                        <label>7</label>
                        <mixed-citation publication-type="journal">7	Murphy, B. P., Pattee, C. H., Gold, A. : Clinical evaluation of a new method for the determination of serum thyroxine. J. Clin. Endoc. 26 : 247, 1966.</mixed-citation>
                    </ref>
                                    <ref id="ref8">
                        <label>8</label>
                        <mixed-citation publication-type="journal">8	Murphy, B. P. : The determination of thyroxine by competitive proteinbinding analysis employing an anion - exchange resin and radiothyronine. J. Lab. Clin. Med. 66 : 161, 1965.</mixed-citation>
                    </ref>
                                    <ref id="ref9">
                        <label>9</label>
                        <mixed-citation publication-type="journal">9	Nauman, J. A., Werner, S. C. : Total and free triiodothyronine in human serum. J. Clin. Invest. 46 : 1346, 1967.</mixed-citation>
                    </ref>
                                    <ref id="ref10">
                        <label>10</label>
                        <mixed-citation publication-type="journal">10	Sterling, K., Bellabarba, D, Newrnan, E. S. and Brenner, M. A : Determination of tri - iodothyronine concantration in human serum. J. Clin. Invest. 48 : 1150, 1969.</mixed-citation>
                    </ref>
                                    <ref id="ref11">
                        <label>11</label>
                        <mixed-citation publication-type="journal">11	Mitchell, M. L., Harden, A. B., O&#039;Rourke, M. E. : The in vitro rain sponge uptake of triiodothyronene - I - 131 from serum in thyroid dise8se and pregnancy. J. Endoc. 20 : 1474, 1960.</mixed-citation>
                    </ref>
                                    <ref id="ref12">
                        <label>12</label>
                        <mixed-citation publication-type="journal">12	— Goolden, A. G., Gartside, J. M. and Osorio, C. : An evaluation of the I - 131 - triiodothyronine resin sponge test. J. Clin. Endoe. 25 : 127, 1965. 13 Clark, F. : Resine uptake of I- 131 triiodothyronine, an invitro test of thyroid function. Lancet, 2 : 167, 1963.</mixed-citation>
                    </ref>
                                    <ref id="ref13">
                        <label>13</label>
                        <mixed-citation publication-type="journal">14 Inada, M. and Sterling, K. : Thyroxine transport in thyrotoxicosig and hypothyroidism. J. Cl.in. Invest. 46 : 1442, 1967.</mixed-citation>
                    </ref>
                                    <ref id="ref14">
                        <label>14</label>
                        <mixed-citation publication-type="journal">15 — Ingbar, S. H., Braverman, L. Dumber, N. A., Lee, G. A. : New methode for measuring the free thyroid hormone in human serum and analysis of the factors that influence its concentration. J.  Clin. Invest. 44 : 1679, 1965.  — Sterling, K., Brenner, M. A. : Free thyroxine in human serum. Simplified measurement with the aid of magnesium presipitation. J. Clin. Invest. 45 : 153, 1966.</mixed-citation>
                    </ref>
                                    <ref id="ref15">
                        <label>15</label>
                        <mixed-citation publication-type="journal">17	— MC Adams, G. B., Reinfrank, R. F. : Resin sponge modification of I - 131 T3 test. J. Nuc. Med. 5 : 112, 1964.</mixed-citation>
                    </ref>
                                    <ref id="ref16">
                        <label>16</label>
                        <mixed-citation publication-type="journal">18	— Quinby, H., Hiza, E. : Evaluation of the Resin uptake of 1- 131 trliodotžwonine as a test of thyroid function. J. Nuc. Med. 5</mixed-citation>
                    </ref>
                            </ref-list>
                    </back>
    </article>
