Ankara Üniversitesi Tıp Fakültesi Mecmuası

0365-8104 1307-5608

Ankara University

Internal Diseases

İç Hastalıkları

Romatoid Artrit ve Safra Taşı

Rheumatoid Arthritis and Gallstones

Özdemir

İlhan

ANKARA ÜNİVERSİRESİ TIP FAKÜLTESİ DAHİLİYE ANABİLİM DALI

06 30 1975

28 1-2 559 562 01 01 1975 06 30 1975

1947

Ankara Üniversitesi Tıp Fakültesi Mecmuası

Tanıları otopsi ile de teyit edilen 83 rumatoid artritli hastaların 48'inde safra kesesi taşı bulundu. Bu safra taşı oranı hastaların o 51.8ini teşkil etmekte olup, yaş-cinse göre yapılan kontrol grubuna oranla (o 26.5) önemli derecede yüksektir(p<0.001). Bu bulgu, rumatoid artritli hastalarda yeni bir sindirim sistemi bozukluğunun olduğunu ortaya koymaktadır

Forty eight of 83 patients with rheumatoid arthritişs which were studied at autopsy had cholelithiasis. This represents a prevalence rate of 57.8 , which is significantly above the rate in a age -sex matched non -rhreumatoid controls (26.5 %). This finding adds a new gastrointestinal abnormality in thepatients with rheumatoid arthritis.

Safra kesesi taşı Romatoid artrit Otopsi

Gallbladder stone (Cholelithiasis) Rheumatoid arthritis Autopsy

1-Barrett - Connor, HK. : Cholelithiasis in sickle cell anemia. Amer. J. Med. 45:889, 1968.

2-Phillips, J. C., Gerald, B. E.: The incidence of cholelithiasis in sickle cell disease. Amer. J. Roentgen. 113:23, 1971.

3-Perrine, R. P. : Cholelithiasis in sickle cell anemia in a caucasian population. Amer, J. Med. 54:327, 1973,

4-Diaz-Buxo, J. A., Hermans, P. BE., Eiveback, L. R.: Prevalence of cholelithiasis in idiopathic late - onset immunoglobulin deficiency. Ann. Intern. Med. 82:213, 1975.

5-Gaster, J.: Surgery of the biliary tract. A five year survey. Arch. Surg. 60:21, 1950.

6-Torvik, A., Hoivik, B. : Gallstones in an autonsy series. Acta chir. Scandinav. 120 : 168, 1960.

7-Horn, G.: Observations on the aeliology of cholelithiasis. Brit. Med. J. II :732, 1956.

8-Blumberg, N., Zisserman, L.: Cholelithiasis: A necropsy study. Rev. Gastroent. 9 : 318, 1942.

9-Kozoll, D. D., Dwyer, G., Meyer, K. A.: Pathologic correlation ot pallstones. A review of 1874 autopsies of patients with gallstones. Arch. Surg. 79:514, 1959.

10-Rains, A. J. H. : Galistones: Causes and treatment, Springfield, Thomas, 1964

11-Small, D. M.: Gallstones. New Eng. J. Med. 279 : 588, 1968.

12-Large, A. M.: On the formation of gallstones. Recent adv. Sur. 54 : 928, 1963.

13-Kaye, M. D., Kern, F.: Clinical relatlonships of galistones. Lancet. 1:1228, 1971.

14-Lieber, M. M.: Incidence of gallstones and their correlation with other diseases. Ann. Surg. 135 :394, 1952.