Ankara Üniversitesi Tıp Fakültesi Mecmuası 0365-8104 1307-5608 Ankara University ​Internal Diseases İç Hastalıkları Otoimmün Tiroid Hastalıkları ve Sekonder Otoimmün Reaksiyonların Müşahede Edildiği Tiroid Rahatsızlıkları: 1 — TİROİDİTLER VE HİPOTİROİDİZM Autoimmune Thyroid Diseases and Thyroid Disorders in Which Secondary Autoimmune Reactions Are Observed: 1 — THYROIDITIS AND HYPOTHYROIDISM Koloğlu Selahattin ANKARA UNIVERSITY, ANKARA FACULTY OF MEDICINE 06 30 1973 26 3 715 736 05 01 1973 06 30 1973 Copyright © 1947, Ankara Üniversitesi Tıp Fakültesi Mecmuası 1947 Ankara Üniversitesi Tıp Fakültesi Mecmuası

A. Ü. Tıp Fakültesi İç Hastalıkları Kliniği Endokrinoloji ve Metabolizma bölümünde yapılan çalışmada, 3 Hashimoto hastalığı, 61 subakut tiroidit vakası ve 22 primer hipotiroidizm vakasında tiroid antikorları ayrıntılı bir şekilde incelenmiştir. Hashimoto hastalığı ve primer erişkin miksödeminde tiroid otoantikorlarının yüksek seviyeleri teyit edilmiş ve bu iki tiroid hastalığının oluş mekanizmalarında otoimmün reaksiyonların rolü tartışılmıştır. Ayrıca, bu yazıda post-radioizotopik hipotiroidizm ile otoimmün reaksiyonlar arasındaki ilişki gözden geçirilmiş ve subakut tiroiditlerde tespit edilen tiroid otoantikorlarının hastalığın seyri sırasında sekonder olarak ortaya çıktığı belirtilmiştir.

In a study conducted in the Endocrinology and Metabolism Department of the Internal Medicine Clinic at A. Ü. Faculty of Medicine, thyroid antibodies were examined in detail in 3 cases of Hashimoto's disease, 61 cases of subacute thyroiditis, and 22 cases of primary hypothyroidism. Elevated levels of thyroid autoantibodies were confirmed in Hashimoto's disease and primary adult myxedema, and the role of autoimmune reactions in the mechanisms of these two thyroid diseases was discussed. Additionally, this paper reviewed the relationship between post-radioisotopic hypothyroidism and autoimmune reactions, and it was noted that thyroid autoantibodies detected in subacute thyroiditis appeared secondarily during the course of the disease.

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