Ankara Üniversitesi Tıp Fakültesi Mecmuası

0365-8104 1307-5608

Ankara University

Medical Genetics (Excl. Cancer Genetics)

Tıbbi Genetik (Kanser Genetiği hariç)

Genetik ve Diabetes Mellitus

Genetics and Diabetes Mellitus

Şaylı

Bekir Sıtkı

ANKARA ÜNİVERSİTESİ, ANKARA TIP FAKÜLTESİ

06 30 1973

26 3 817 840 05 01 1973 05 30 1973

1947

Ankara Üniversitesi Tıp Fakültesi Mecmuası

Diabetes mellitus is one of disorders of carbohydrate metabolism, according to several authors, present at the time of conception of the individual. in fact, there are several lines of evidence indicating that the heredity plays an important role in the genesis of the disease. These are given as familial aggregation, monozygotic twin concordance, pedigree patterns and animal models. The associated syndro mes, population studies and different pathological investigations also support this view of hereditary basis.Despite these observations and some but limited experiments, the mode of transmission has not been yet established and it seems impossible at the present stage of our knowledge to decide which of the different kinds of transmission is involved. This, of course, is due to difficulties of ascertainement and that the basic defect, whether central or peripheral, macroscopic or microscopic, molecular or enzymatic, is almost completely unknown.

Genetik diabetes mellitusdan söz edilmesine ve bu anlayışın haklılığının çeşitli metodlarla desteklenmesine rağmen, hastalığın kalıtım yolu bilinmemektedir. öte yandan, kondisyona yol açan temel kusur açık değildir. O nedenle ileri sürülen çeşitli hipotezler ve teklif olunan santral veya periferik, makroskopik veya moleküler modeller henüz tartışmasız kabul edilememektedir.

Diabetes Mellitus Genetics Prevalence

Diabetes Mellitus Genetik Prevalans

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