<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.4 20241031//EN"
        "https://jats.nlm.nih.gov/publishing/1.4/JATS-journalpublishing1-4.dtd">
<article  article-type="case-report"        dtd-version="1.4">
            <front>

                <journal-meta>
                                    <journal-id></journal-id>
            <journal-title-group>
                                                                                    <journal-title>Ankara Üniversitesi Tıp Fakültesi Mecmuası</journal-title>
            </journal-title-group>
                            <issn pub-type="ppub">0365-8104</issn>
                                        <issn pub-type="epub">1307-5608</issn>
                                                                                            <publisher>
                    <publisher-name>Ankara University</publisher-name>
                </publisher>
                    </journal-meta>
                <article-meta>
                                        <article-id/>
                                                                <article-categories>
                                            <subj-group  xml:lang="en">
                                                            <subject>Infectious Diseases</subject>
                                                    </subj-group>
                                            <subj-group  xml:lang="tr">
                                                            <subject>Bulaşıcı Hastalıklar</subject>
                                                    </subj-group>
                                    </article-categories>
                                                                                                                                                        <title-group>
                                                                                                                        <article-title>Difteri ile Karışık Bir Şarbon Enfeksiyonu</article-title>
                                                                                                                                                                                                <trans-title-group xml:lang="en">
                                    <trans-title>An Anthrax Infection Complicated by Diphtheria</trans-title>
                                </trans-title-group>
                                                                                                    </title-group>
            
                                                    <contrib-group content-type="authors">
                                                                        <contrib contrib-type="author">
                                                                <name>
                                    <surname>Onul</surname>
                                    <given-names>Behiç</given-names>
                                </name>
                                                                    <aff>ANKARA UNIVERSITY, ANKARA FACULTY OF MEDICINE</aff>
                                                            </contrib>
                                                                                </contrib-group>
                        
                                        <pub-date pub-type="pub" iso-8601-date="19511231">
                    <day>12</day>
                    <month>31</month>
                    <year>1951</year>
                </pub-date>
                                        <volume>5</volume>
                                        <issue>3-4</issue>
                                        <fpage>129</fpage>
                                        <lpage>134</lpage>
                        
                        <history>
                                    <date date-type="received" iso-8601-date="19510303">
                        <day>03</day>
                        <month>03</month>
                        <year>1951</year>
                    </date>
                                                    <date date-type="accepted" iso-8601-date="19510506">
                        <day>05</day>
                        <month>06</month>
                        <year>1951</year>
                    </date>
                            </history>
                                        <permissions>
                    <copyright-statement>Copyright © 1947, Ankara Üniversitesi Tıp Fakültesi Mecmuası</copyright-statement>
                    <copyright-year>1947</copyright-year>
                    <copyright-holder>Ankara Üniversitesi Tıp Fakültesi Mecmuası</copyright-holder>
                </permissions>
            
                                                                                                <abstract><p>Bu çalışma, Ankara&#039;nın Karakaş köyünde yaşayan 40 yaşında bir erkek hastada görülen, şarbon ve difteri basillerinin birleştiği nadir bir vakayı sunmaktadır. Sol göz kapağında şarbon püstülü ve ödemiyle başlayan hastalık, başlangıçta uygulanan şarbon serumu ile gerilemiş ancak iyileşme süreci duraksamıştır. Yapılan derinlemesine bakteriyolojik incelemeler, yara üzerinde mebzul miktarda difteri basili ürediğini ortaya koymuştur. Şarbon nekrozu üzerine eklenen yara difterisi tablosu, özel lokal ve genel difteri tedavisiyle kontrol altına alınmıştır. Makale, klinik olarak şarbona benzeyen ancak iyileşmeyen yaralarda başka ajanların da aranması gerektiğini vurgularken; hastaya 25 gün arayla yapılan mükerrer serum uygulamalarının immünolojik sonuçlarını da (serum hastalığı ve anafilaksi yönetimi) tartışmaktadır.</p></abstract>
                                                                                                                                    <trans-abstract xml:lang="en">
                            <p>This case report describes a unique clinical occurrence in a 40-year-old farmer from Ankara who initially contracted a cutaneous anthrax infection on his lower eyelid. Despite receiving successful anthrax serum treatment which resolved the systemic edema, the localized necrotic pustule failed to heal and began to expand. Microbiological investigations revealed that the wound had been secondarily infected with diphtheria bacilli (Corynebacterium diphtheriae). The study details the diagnostic challenges of mixed infections, where one pathogen masks another. After the administration of diphtheria antitoxin using the Besredka method, the patient showed rapid improvement and achieved full recovery. The paper also discusses immunological aspects of repeated serum treatments and emphasizes the need to search for secondary pathogens in non-healing anthrax lesions.</p></trans-abstract>
                                                            
            
                                                            <kwd-group>
                                                    <kwd>Şarbon Püstülü</kwd>
                                                    <kwd>  Difteri</kwd>
                                                    <kwd>  Karma Enfeksiyon</kwd>
                                                    <kwd>  Serum Hastalığı</kwd>
                                            </kwd-group>
                                                        
                                                                            <kwd-group xml:lang="en">
                                                    <kwd>Anthrax Pustule</kwd>
                                                    <kwd>  Diphtheria</kwd>
                                                    <kwd>  Mixed Infection</kwd>
                                                    <kwd>  Serum Sickness</kwd>
                                            </kwd-group>
                                                                                                            </article-meta>
    </front>
    <back>
                            <ref-list>
                                    <ref id="ref1">
                        <label>1</label>
                        <mixed-citation publication-type="journal">Onul, B. (1951). Difteri ile karışık bir şarbon enfeksiyonu. Ankara Üniversitesi Tıp Fakültesi Mecmuası, 5(1-2), 129-134.</mixed-citation>
                    </ref>
                            </ref-list>
                    </back>
    </article>
