ankara univ vet fak derg Ankara Üniversitesi Veteriner Fakültesi Dergisi 1300-0861 1308-2817 Ankara University 10.1501/Vetfak_0000002849 Veterinary Surgery Veteriner Cerrahi Ruminal fermentasyonun modifikasyonunda antibiyotiklerin alternatifi olarak bitki ekstraktları vesekonder bitki metabolitlerine genel bir bakış Overview of plant extracts and plant secondary metabolites as alternatives to antibiotics for modification of ruminal fermentation Demirtaş Ahu Öztürk Hakan Pişkin İlksin 06 01 2018 65 2 213 217 06 01 2018 Copyright © 1954, Ankara Üniversitesi Veteriner Fakültesi Dergisi 1954 Ankara Üniversitesi Veteriner Fakültesi Dergisi

İyonofor grubu antibiyotiklerin subterapötik dozları ruminal fermantasyonun verimliliğini artırmak için 1970’li yıllardan itibaren kullanılmaya başlamıştır. Fakat hayvansal ürünlerde kalıntı bırakma ve bakterilerde direnç oluşturma riskleri nedeniyle yem katkı maddesi olarak antibiyotiklerin kullanımı 2006 yılından itibaren Avrupa Birliği ülkelerinde ve Türkiye’de yasaklanmıştır. Bu yasak ruminal fermantasyonu değiştirerek ruminant verimliliğini yükseltmek amacıyla antibiyotiklere alternatif olabilecek bitki ekstraktları ve bunların sekonder metabolitleri gibi daha güvenli maddeler üzerine yoğun araştırmalar yapılmasına neden olmuştur. Bu derlemede, ruminal fermantasyonun modifikasyonunda kullanılan bitki ekstraktları ve ikincil bitki metabolitleri ile ilgili genel ve güncel bilgiler özetlenmiştir. Ayrıca bu maddelerin potansiyel faydaları ve olası dezavantajları da tartışılmıştır

Ionophore antibiotics in sub-therapeutic doses have been used since 1970s to improve ruminal fermentation. But use of antibiotics as feed additives was banned in the European Union and Turkey in 2006 since they leave residues in animal products and develop resistance in bacteria. This has shifted the focus of the studies to safer alternatives such as plant extracts and their secondary metabolites to alter ruminal fermentation in order to improve ruminant productivity. In this review, general and recent knowledge about plant extracts and plant secondary metabolites as modifiers of ruminal fermentation are summarized. Furthermore, potential efficacies and possible disadvantages of these substances are also discussed

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