ankara univ vet fak derg Ankara Üniversitesi Veteriner Fakültesi Dergisi 1300-0861 1308-2817 Ankara University 10.33988/auvfd.834133 Veterinary Surgery Veteriner Cerrahi The role of bio-detection dogs in the prevention and diagnosis of infectious diseases: A systematic review https://orcid.org/0000-0003-3869-3749 Salgırlı Demirbaş Yasemin ANKARA ÜNİVERSİTESİ https://orcid.org/0000-0001-9992-8738 Baş Bülent ANKARA ÜNİVERSİTESİ https://orcid.org/0000-0003-2913-2069 Öztürk Hakan ANKARA ÜNİVERSİTESİ https://orcid.org/0000-0003-3414-4697 Kismali Gorkem ANKARA ÜNİVERSİTESİ https://orcid.org/0000-0002-8782-9561 Alpay Merve DÜZCE ÜNİVERSİTESİ https://orcid.org/0000-0002-3783-8064 Seçilmiş Canbay Hale BURDUR MEHMET AKİF ERSOY ÜNİVERSİTESİ https://orcid.org/0000-0002-4974-2940 Emen Fatih BURDUR MEHMET AKİF ERSOY ÜNİVERSİTESİ https://orcid.org/0000-0002-2212-2610 Sareyyüpoğlu Barış ANKARA ÜNİVERSİTESİ https://orcid.org/0000-0001-5008-9443 Özkul Aykut ANKARA ÜNİVERSİTESİ 03 31 2021 68 2 185 192 12 01 2020 03 16 2021 Copyright © 1954, Ankara Üniversitesi Veteriner Fakültesi Dergisi 1954 Ankara Üniversitesi Veteriner Fakültesi Dergisi

Infectious diseases have been lately considered as one of the most important global risks, which negatively impact not only the health but also the socioeconomic conditions of countries. Globalization influences the spread of infectious diseases as a result of increased travelling and interaction in humans. Thus, it is highly important to prevent and diagnose new infectious diseases by using accurate and quick diagnostic methods. Bio-detection dogs have a great potential to accurately diagnose infectious disease as they have a great ability to sense disease-specific volatile organic compounds (VOCs) originate from infectious agents and/or pathophysiological processes in the human body. The use of these dogs to detect infectious diseases has come to focus in particular after the recent global health crisis due to the SARS-CoV-2 infection. This review discusses the potential use of bio-detection dogs in the prevention and diagnosing of infectious diseases. Moreover, factors affecting the scent of the disease, e.g. VOCs, are tried to be highlighted.

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