Diyabet Tedavisinde Antioksidan Etki: Alfa Lipoik Asit

Year 2024, Volume: 7 Issue: 1, 68 - 74, 29.01.2024

Umut Dalmış , Emine Merve Ekici

https://doi.org/10.53493/avrasyasbd.1344385

Abstract

Alfa lipoik asit besinlerde bulunmasının yanı sıra vücutta da sentezlenebilen bir maddedir. Alfa lipoik asit hem suda hem de yağda çözünebilen tek antioksidan olup ve glutatyon, C ve E vitamini gibi diğer antioksidanların yeniden kullanılmasını sağlamaktadır. Hem kendisi hem de indirgenmiş formu olan dihidrolipoik asit antioksidan özellik gösterir. Ağır metaller ile şelat oluşturarak vücuttaki toksin etkilerini azaltabilir. Ayıca insülin sinyal yolaklarında yer almaktadır. Bu özellikleri sayesinde önemli bir antioksidan olarak kabul edilmektedir. Günümüzde artan kronik hastalıklardan birisi olan diyabet ve diyabetin komplikasyonlarını azaltmaya yönelik çeşitli çalışmalar yapılmaktadır. Bu derlemede alfa lipoik asit ve diyabet arasındaki ilişkiyi değerlendirmek amaçlanmaktadır.

Keywords

Diyabet, alfa lipoik asit, antioksidan

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