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MULTIPLE LARGE PERIPHERAL GIANT CELL GRANULOMA: A CASE REPORT

Year 2015, Volume: 4 Issue: 2, 103 - 106, 31.08.2015

Abstract


Peripheral giant cell granuloma (PGCG) is the most common oral giant cell lesion. PGCG presumably does not represent a true neoplasm. PGCG is believed to be stimulated by local irritation or trauma besides the causing of PGCG isn’t known exactly. PGCG affects women more frequent than men and mandible more often than maksilla. It is usually seen as red or redhiss-blue, noduler mass on the gingiva or edentulous ridge. In the case report; multiple large PGCGs of 48 years old male patient causing facial asymmetry, localizated on the gingiva including the alveolar ridge of his maxillary left central incisor-right canin region and mandibular right central incisor-left canin region is presented. This case report contains radiological, clinical, histopathological findings, as well as diagnosis, treatment, follow-up of 6 months after totally excision of multiple PGCSs


References

  • 1. Tandon PN, Gupta SK, Gupta DS, Jurel SK, Saraswat A. Peripheral giant cell granuloma. Contemp Clin Dent 2012;3(Suppl 1):S118-21.
  • 2. Neville BW, Damm DD, Allen CM, Bouquot JE. Oral and maxillofacial pathology, 2th edition, p.449-50, W.B. Saunders Co., Philadelphia (2002).
  • 3. Kfir Y, Buchner A, Hansen LS. Reactive lesions of the gingiva. A clinicopathological study of 741 cases. J Periodontol 1980;51(11):655-61.
  • 4. Flaitz CM. Peripheral giant cell granuloma: a potentially aggressive lesion in children. Pediatr Dent 2000;22(3):232-3.
  • 5. Mannem S, Chava VK. Management of an unusual peripheral giant cell granuloma: A diagnostic dilemma. Contemp Clin Dent 2012;3(1):93–6.
  • 6. Bodner L, Peist M, Gatot A, Fliss DM. Growth potential of peripheral giant cell granuloma. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1997;83(5):548-51.
  • 7. Barış E, Gültekin SE, Bozkaya S. A clinicopathologic evaluation of peripheral giant cell granulomas. J Dent Fac Atatürk Uni 2010;20(2):79-83.
  • 8. Katsikeris N, Kakarantza-Angelopoulou E, Angelopoulos AP. Peripheral giant cell granuloma. Clinicopathologic study of 224 new cases and review of 956 reported cases. Int J Oral Maxillofac Surg 1988;17(2):94-9.
  • 9. Lester SR, Cordell KG, Rosebush MS, Palaiologou AA, Maney P. Peripheral giant cell granulomas: a series of 279 cases. Oral Surg Oral Med Oral Pathol Oral Radiol 2014;118(4):475-82.
  • 10. Regezi JA, Sciubba JJ, Jordan RCK. Oral pathology, clinical pathologic correlations, 4 th ed, p.116-7, W.B. Saunders Co.,. Philadelphia (2003)
  • 11. Kibar S, Yılmaz H, Erdoğan BA, Şanlı A, Kayahan S. Sert Damakta Periferik Dev Hücreli Granülom. İstanbul Med J 2013;14:136-9.
  • 12. Smith BR, Fowler CB, Svane TJ. Primary hyperparathyroidism presenting as a “peripheral” giantcell granuloma. J Oral Maxillofac Surg. 1988;46(1):65-9.
  • 13. Burkes EJ, White RP. A peripheral giant-cell granuloma manifestation of primary hyperparathyroidism: report of case. J Am Dent Assoc 1989;118(1):62-4.14.
  • 14. Cayci E, Kan B, Guzeldemir-Akcakanat E, Muezzinoglu B. Peripheral giant cell reparative granuloma of maxilla in a patient with aggressive periodontitis. Oral Health Dent Manag 2014;13(3):638-41.

BÜYÜK BOYUTLARDA MULTİPL PERİFERAL DEV HÜCRELI GRANÜLOM: VAKA RAPORU

Year 2015, Volume: 4 Issue: 2, 103 - 106, 31.08.2015

Abstract


Periferal dev hücreli granülom (PDHG) oral bölgenin sık izlenen dev hücreli bir lezyonudur. PDHG’ler gerçek bir neoplazmı temsil etmezler. Etyolojileri çok açık olmayan bu lezyonların, travma veya lokal irritasyonlara bağlı gelişen reaktif bir lezyon olduğu düşünülmektedir. PDHG’lere kadınlarda erkeklere oranla daha sık, mandibulada ise maksilladan daha fazla rastlanılır. Gingiva veya dişsiz alveolar kret üzerinde kırmızı, kırmızı-mavi nodüler kitle şeklinde görülürler. Bu olgu raporunda, 48 yaşında erkek hastada görülen, maksilla sol santral kesici - sağ kanin kesici dişler ve mandibula sağ santral kesici-sol kanin kesici dişler bölgesinde lokalize, yüzde asimetriye neden olan büyük boyutlu PDHG’ler sunulmuştur. Multipl PDHG vakasının radyolojik, klinik, histopatolojik bulguları ile birlikte teşhis, tedavi ve 6 aylık takibi rapor edilmiştir.


References

  • 1. Tandon PN, Gupta SK, Gupta DS, Jurel SK, Saraswat A. Peripheral giant cell granuloma. Contemp Clin Dent 2012;3(Suppl 1):S118-21.
  • 2. Neville BW, Damm DD, Allen CM, Bouquot JE. Oral and maxillofacial pathology, 2th edition, p.449-50, W.B. Saunders Co., Philadelphia (2002).
  • 3. Kfir Y, Buchner A, Hansen LS. Reactive lesions of the gingiva. A clinicopathological study of 741 cases. J Periodontol 1980;51(11):655-61.
  • 4. Flaitz CM. Peripheral giant cell granuloma: a potentially aggressive lesion in children. Pediatr Dent 2000;22(3):232-3.
  • 5. Mannem S, Chava VK. Management of an unusual peripheral giant cell granuloma: A diagnostic dilemma. Contemp Clin Dent 2012;3(1):93–6.
  • 6. Bodner L, Peist M, Gatot A, Fliss DM. Growth potential of peripheral giant cell granuloma. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1997;83(5):548-51.
  • 7. Barış E, Gültekin SE, Bozkaya S. A clinicopathologic evaluation of peripheral giant cell granulomas. J Dent Fac Atatürk Uni 2010;20(2):79-83.
  • 8. Katsikeris N, Kakarantza-Angelopoulou E, Angelopoulos AP. Peripheral giant cell granuloma. Clinicopathologic study of 224 new cases and review of 956 reported cases. Int J Oral Maxillofac Surg 1988;17(2):94-9.
  • 9. Lester SR, Cordell KG, Rosebush MS, Palaiologou AA, Maney P. Peripheral giant cell granulomas: a series of 279 cases. Oral Surg Oral Med Oral Pathol Oral Radiol 2014;118(4):475-82.
  • 10. Regezi JA, Sciubba JJ, Jordan RCK. Oral pathology, clinical pathologic correlations, 4 th ed, p.116-7, W.B. Saunders Co.,. Philadelphia (2003)
  • 11. Kibar S, Yılmaz H, Erdoğan BA, Şanlı A, Kayahan S. Sert Damakta Periferik Dev Hücreli Granülom. İstanbul Med J 2013;14:136-9.
  • 12. Smith BR, Fowler CB, Svane TJ. Primary hyperparathyroidism presenting as a “peripheral” giantcell granuloma. J Oral Maxillofac Surg. 1988;46(1):65-9.
  • 13. Burkes EJ, White RP. A peripheral giant-cell granuloma manifestation of primary hyperparathyroidism: report of case. J Am Dent Assoc 1989;118(1):62-4.14.
  • 14. Cayci E, Kan B, Guzeldemir-Akcakanat E, Muezzinoglu B. Peripheral giant cell reparative granuloma of maxilla in a patient with aggressive periodontitis. Oral Health Dent Manag 2014;13(3):638-41.
There are 14 citations in total.

Details

Primary Language Turkish
Journal Section Olgu sunumları
Authors

Mustafa Gümüşok

Murat Özle This is me

Begüm Okur This is me

Anıl Seçkin This is me

Farid Museyibov This is me

Özlem Üçok This is me

Sedat Çetiner This is me

Publication Date August 31, 2015
Submission Date December 19, 2014
Published in Issue Year 2015 Volume: 4 Issue: 2

Cite

APA Gümüşok, M., Özle, M., Okur, B., Seçkin, A., et al. (2015). BÜYÜK BOYUTLARDA MULTİPL PERİFERAL DEV HÜCRELI GRANÜLOM: VAKA RAPORU. Balıkesir Sağlık Bilimleri Dergisi, 4(2), 103-106.

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