BibTex RIS Cite
Year 2015, Volume: 32 Issue: 3, 291 - 295, 01.07.2015

Abstract

References

  • 1. Menon NJ, Amin AM, Mohammed A, Hamilton G. Acute mesenteric ischaemia. Acta Chir Belg 2005;105:344-54.
  • 2. Yasuhara H. Acute mesenteric ischemia: the challenge of gastroenterology. Surg Today 2005;35:185-95. [CrossRef]
  • 3. Christopher MB. Fernandes Mesenteric Ischemia. http://www. emedicine.com/EMERG/topic311.htm. Accessed: 13.09.2006.
  • 4. Carrol ED, Thomson AP, Hart CA. Procalcitonin as a marker of sepsis. Int J Antimicrob Agents 2002;20:1-9. [CrossRef]
  • 5. Massaro KS, Costa SF, Leone C, Chamone DA. Procalcitonin (PCT) and C-reactive protein (CRP) as severe systemic infection markers in febrile neutropenic adults. BMC Infect Dis 2000;7:137. [CrossRef]
  • 6. Burtis CA, Ashwood ER. Klinik Kimyada Temel İlkeler. Palme Yayınları, 5th Ed. Ankara, 2005, p. 450-2.
  • 7. Assıcat M, Gendrel D, Carsin H, Raymond J, Guılbaud J, Bohuon C. High serum procalcitonin concentrations in patients with sepsis and infections. Lancet 1993;341:515-8. [CrossRef]
  • 8. Yasuhara H. Acute mesenteric ischemia: the challenge of gastroenterology. Surg Today 2005;35:185-95. [CrossRef]
  • 9. Kozuch PL, Brandt LJ. Review article: diagnosis and management of mesenteric ischaemia with an emphasis on pharmacotherapy. Aliment Pharmacol Ther 2005;21:201-15. [CrossRef]
  • 10. Lange H, Jackel R. Usefulness of plasma lactate concentration in the diagnosis of acute abdominal disease. Eur J Surg 1994;160:381-4.
  • 11. Kulaçoğlu H, Kocaerkek Z, Moran M, Kulah B, Atay Ç, Kulaçoğlu S. Diagnostic value of blood D-dimer level in acute mesenteric ischaemia in the rat: An experimental study. Asian J Surg 2005;28:131-5. [CrossRef]
  • 12. Meyer T, Klein P, Schweiger H, Lang W. How can the prognosis of acute mesenteric artery ischemia be improved? Results of a retrospektive analysis. Zentralbl Chir 1998;123:230-4.
  • 13. Acosta S, Ogren M, Sternby NH, Bergqvist D, Bjorck M. Clinical implications for the management of acute thromboembolic occlusion of the superior mesenteric artery: autopsy findings in 213 patients. Ann Surg 2005;241:516-22. [CrossRef]
  • 14. Altinyollar H, Boyabatli M, Berberoglu U. D-dimer as a marker for early diagnosis of acute mesenteric ischemia. Thromb Res 2006;117:463-7. [CrossRef]
  • 15. Kurt Y, Akin ML, Demirbas S, Uluutku AH, Gulderen M, Avsar K, Celenk T. D-dimer in the early diagnosis of acute mesenteric ischemia secondary to arterial occlusion in rats. Eur Surg Res 2005;37:216-9. [CrossRef]
  • 16. Rau B, Steinbech G, Baum gart K, Gansauge F, Beger HG. The clinical value of procalcitonin in the prediction of infected necrosis in acute pancreatitis. Intensive Care Med 2000;26:159-64. [CrossRef]
  • 17. Meisner M. Pathobiochemistry and clinical use of procalcitonin. Clin Chim Acta 2002;323:17-29. [CrossRef]
  • 18. Becker KL, Nylen ES, Cohen R, Snider RH. Calcitonin: Structure, molecular biology, and actions. Principles of Bone Biology. Academic Press Inc.; 1996. p. 471-4.
  • 19. Guven H, Altıntop L, Baydın A, Esen S. Diagnostic value of procalcitonin levels as an early indicator of sepsis. Am J Emerg Med 2002;20:202-6. [CrossRef]
  • 20. Steinwald PM, Whang KT, Becker KL, Snider RH, Nylen ES, White JC. Elevated calcitonin precursor levels are related to mortality in an animal model of sepsis. Crit Care 1999;3:11-6. [CrossRef]
  • 21. Karabulut K, Gül M, Dündar ZD, Cander B, Kurban S, Toy H. Diagnostic and prognostic value of procalcitonin and phosphorus in acute mesenteric ischemia. Ulus Travma Acil Cerrahi Derg 2011;17:193-8. [CrossRef]

Diagnostic Value of Procalcitonin Levels in Acute Mesenteric Ischemia

Year 2015, Volume: 32 Issue: 3, 291 - 295, 01.07.2015

Abstract

Background: Acute mesenteric ischemia (AMI) is a potentially fatal disease. Difficulties in diagnosis make it essential to find early biomarkers. Aims: This study investigated the diagnostic value of procalcitonin (PCT) levels in AMI. Study Design: Animal experimentation.  Methods: Rats were divided into six groups of six animals each. In the experimental group, an experimental ischemia model was established by clamping the superior mesenteric artery from the aortic outflow tract. Blood and tissue specimens were collected from rats in the experimental mesenteric ischemia model at 30 min and 2 and 6 h, and these were compared with specimens from the respective control groups. PCT levels were compared at 30 min and 2 and 6 h. Results: PCT levels were 185.3 pg/mL in the control group and 219.3 pg/mL in the study group, 199.6 pg/mL in the control group and 243.9 pg/mL in the study group, and 201.9 pg/mL in the control group and 286.9 pg/mL in the study group, respectively, at 30 minute, 2 and 6 hours. Significant differences were determined between 6-h control group and ischemia group PCT levels (p=0.005). Conclusion: The absence of a significant increase in PCT levels in the early period, while a significant difference was detected in the later period (6 h), shows that PCT levels rise late in mesenteric ischemia and can be a marker in the late period.

References

  • 1. Menon NJ, Amin AM, Mohammed A, Hamilton G. Acute mesenteric ischaemia. Acta Chir Belg 2005;105:344-54.
  • 2. Yasuhara H. Acute mesenteric ischemia: the challenge of gastroenterology. Surg Today 2005;35:185-95. [CrossRef]
  • 3. Christopher MB. Fernandes Mesenteric Ischemia. http://www. emedicine.com/EMERG/topic311.htm. Accessed: 13.09.2006.
  • 4. Carrol ED, Thomson AP, Hart CA. Procalcitonin as a marker of sepsis. Int J Antimicrob Agents 2002;20:1-9. [CrossRef]
  • 5. Massaro KS, Costa SF, Leone C, Chamone DA. Procalcitonin (PCT) and C-reactive protein (CRP) as severe systemic infection markers in febrile neutropenic adults. BMC Infect Dis 2000;7:137. [CrossRef]
  • 6. Burtis CA, Ashwood ER. Klinik Kimyada Temel İlkeler. Palme Yayınları, 5th Ed. Ankara, 2005, p. 450-2.
  • 7. Assıcat M, Gendrel D, Carsin H, Raymond J, Guılbaud J, Bohuon C. High serum procalcitonin concentrations in patients with sepsis and infections. Lancet 1993;341:515-8. [CrossRef]
  • 8. Yasuhara H. Acute mesenteric ischemia: the challenge of gastroenterology. Surg Today 2005;35:185-95. [CrossRef]
  • 9. Kozuch PL, Brandt LJ. Review article: diagnosis and management of mesenteric ischaemia with an emphasis on pharmacotherapy. Aliment Pharmacol Ther 2005;21:201-15. [CrossRef]
  • 10. Lange H, Jackel R. Usefulness of plasma lactate concentration in the diagnosis of acute abdominal disease. Eur J Surg 1994;160:381-4.
  • 11. Kulaçoğlu H, Kocaerkek Z, Moran M, Kulah B, Atay Ç, Kulaçoğlu S. Diagnostic value of blood D-dimer level in acute mesenteric ischaemia in the rat: An experimental study. Asian J Surg 2005;28:131-5. [CrossRef]
  • 12. Meyer T, Klein P, Schweiger H, Lang W. How can the prognosis of acute mesenteric artery ischemia be improved? Results of a retrospektive analysis. Zentralbl Chir 1998;123:230-4.
  • 13. Acosta S, Ogren M, Sternby NH, Bergqvist D, Bjorck M. Clinical implications for the management of acute thromboembolic occlusion of the superior mesenteric artery: autopsy findings in 213 patients. Ann Surg 2005;241:516-22. [CrossRef]
  • 14. Altinyollar H, Boyabatli M, Berberoglu U. D-dimer as a marker for early diagnosis of acute mesenteric ischemia. Thromb Res 2006;117:463-7. [CrossRef]
  • 15. Kurt Y, Akin ML, Demirbas S, Uluutku AH, Gulderen M, Avsar K, Celenk T. D-dimer in the early diagnosis of acute mesenteric ischemia secondary to arterial occlusion in rats. Eur Surg Res 2005;37:216-9. [CrossRef]
  • 16. Rau B, Steinbech G, Baum gart K, Gansauge F, Beger HG. The clinical value of procalcitonin in the prediction of infected necrosis in acute pancreatitis. Intensive Care Med 2000;26:159-64. [CrossRef]
  • 17. Meisner M. Pathobiochemistry and clinical use of procalcitonin. Clin Chim Acta 2002;323:17-29. [CrossRef]
  • 18. Becker KL, Nylen ES, Cohen R, Snider RH. Calcitonin: Structure, molecular biology, and actions. Principles of Bone Biology. Academic Press Inc.; 1996. p. 471-4.
  • 19. Guven H, Altıntop L, Baydın A, Esen S. Diagnostic value of procalcitonin levels as an early indicator of sepsis. Am J Emerg Med 2002;20:202-6. [CrossRef]
  • 20. Steinwald PM, Whang KT, Becker KL, Snider RH, Nylen ES, White JC. Elevated calcitonin precursor levels are related to mortality in an animal model of sepsis. Crit Care 1999;3:11-6. [CrossRef]
  • 21. Karabulut K, Gül M, Dündar ZD, Cander B, Kurban S, Toy H. Diagnostic and prognostic value of procalcitonin and phosphorus in acute mesenteric ischemia. Ulus Travma Acil Cerrahi Derg 2011;17:193-8. [CrossRef]
There are 21 citations in total.

Details

Other ID JA35CS85SU
Journal Section Research Article
Authors

Yunus Karaca This is me

Abdulkadir Gündüz This is me

Süha Türkmen This is me

Süleyman Türedi This is me

Ahmet Menteşe This is me

Süleyman Caner Karahan This is me

Umut Eryiğit This is me

Publication Date July 1, 2015
Published in Issue Year 2015 Volume: 32 Issue: 3

Cite

APA Karaca, Y., Gündüz, A., Türkmen, S., Türedi, S., et al. (2015). Diagnostic Value of Procalcitonin Levels in Acute Mesenteric Ischemia. Balkan Medical Journal, 32(3), 291-295.
AMA Karaca Y, Gündüz A, Türkmen S, Türedi S, Menteşe A, Karahan SC, Eryiğit U. Diagnostic Value of Procalcitonin Levels in Acute Mesenteric Ischemia. Balkan Medical Journal. July 2015;32(3):291-295.
Chicago Karaca, Yunus, Abdulkadir Gündüz, Süha Türkmen, Süleyman Türedi, Ahmet Menteşe, Süleyman Caner Karahan, and Umut Eryiğit. “Diagnostic Value of Procalcitonin Levels in Acute Mesenteric Ischemia”. Balkan Medical Journal 32, no. 3 (July 2015): 291-95.
EndNote Karaca Y, Gündüz A, Türkmen S, Türedi S, Menteşe A, Karahan SC, Eryiğit U (July 1, 2015) Diagnostic Value of Procalcitonin Levels in Acute Mesenteric Ischemia. Balkan Medical Journal 32 3 291–295.
IEEE Y. Karaca, A. Gündüz, S. Türkmen, S. Türedi, A. Menteşe, S. C. Karahan, and U. Eryiğit, “Diagnostic Value of Procalcitonin Levels in Acute Mesenteric Ischemia”, Balkan Medical Journal, vol. 32, no. 3, pp. 291–295, 2015.
ISNAD Karaca, Yunus et al. “Diagnostic Value of Procalcitonin Levels in Acute Mesenteric Ischemia”. Balkan Medical Journal 32/3 (July 2015), 291-295.
JAMA Karaca Y, Gündüz A, Türkmen S, Türedi S, Menteşe A, Karahan SC, Eryiğit U. Diagnostic Value of Procalcitonin Levels in Acute Mesenteric Ischemia. Balkan Medical Journal. 2015;32:291–295.
MLA Karaca, Yunus et al. “Diagnostic Value of Procalcitonin Levels in Acute Mesenteric Ischemia”. Balkan Medical Journal, vol. 32, no. 3, 2015, pp. 291-5.
Vancouver Karaca Y, Gündüz A, Türkmen S, Türedi S, Menteşe A, Karahan SC, Eryiğit U. Diagnostic Value of Procalcitonin Levels in Acute Mesenteric Ischemia. Balkan Medical Journal. 2015;32(3):291-5.