Historical and recent aspects of boron in human and animal health
Abstract
Evidence that boron is a beneficial bioactive trace element is substantial. The evidence has come from numerous laboratories that have use a variety of experimental models, including humans. In nutritional amounts, boron promotes bone health and brain function, modulates the immune or inflammatory response, and influences the response to oxidative stress. Boron apparently has diverse effects through influencing a cell signaling system or the formation and/or activity of an entity involved in many biochemical processes. Based on findings from both animal and human experiments, and intake of boron near 1.0 mg/day would be a reasonable suggestion for an adequate intake that would assure the benefits provided by boron.
Increased intakes of boron through
consuming fruits, vegetables, nuts, and pulses should be recognized as a
reasonable dietary recommendation.
Keywords
References
- [1] Hunt C. D., Dietary boron: Evidence for essentiality and homeostatic control in humans and animals, Advances in Plant and Animal Boron Nutrition, Springer, Dordrecht, The Netherlands, pp. 251-267, 2007.
- [2] Fort D. J., Rogers R. L., McLaughlin D. W., Sellers C. M., Schlekat C. L., Impact of boron deficiency on Xenopus laevis, A summary of biological effects and potential biochemical roles, Biol. Trace Elem. Res., 90, 117-142, 2002.
- [3] Rowe R. I., Eckhert C. D., Boron is required for zebrafish embryogenesis, J. Exp. Biol., 12, 221-233, 1999.
- [4] Hunt C. D., Nielsen F. H., Interaction between boron and cholecalciferol in the chick, Trace Elements Metabolism in Man and Animals, TENA-4, Australian Academy of Science, Canberra, Australia, pp. 597-600, 1981.
- [5] Hunt C. D., Herbel J. L., Idso J. P., Dietary boron modifies the effects of vitamin D3 nutriture on indices of energy substrate utilization and mineral metabolism in the chick, J. Bone Miner. Res., 9, 171-181, 1994.
- [6] Armstrong T. A., Spears J. W., Crenshaw T. D., Nielsen F. H., Boron supplementation of a semipurified diet for weanling pigs improves feed efficiency and bone strength characteristics and alters plasma lipid metabolites, J. Nutr., 139, 2575-2581, 2000.
- [7] Nielsen F. H., Dietary fat composition modifies the effect of boron on bone characteristics and plasma lipids in rats, BioFactors, 20, 161-171, 2004.
- [8] Gorustovich A. A., Steimetz T., Nielsen F. H., Guglielmotti M. B., Histomorphometric study of alveolar bone healing in rats fed a boron-deficient diet, Anatomical Record (Hoboken), 291, 441-447, 2008.
Details
Primary Language
English
Subjects
-
Journal Section
Review
Authors
Forrest Harold Nielsen
*
This is me
0000-0001-9557-4792
Publication Date
December 30, 2017
Submission Date
March 23, 2017
Acceptance Date
December 21, 2017
Published in Issue
Year 2017 Volume: 2 Number: 3