Clinical Outcomes of Radioactive Iodine Therapy in a Patient with Myasthenia Gravis and Hyperthyroidism
Abstract
Myasthenia Gravis is an autoimmune disease characterized with muscle weakness and fatigue. Hyperthyroidism can be present with Myasthenia Gravis with a rate of 2-17.5
%. It is known that hyperthyroidism affects the clinical course of myasthenia gravis. A
27 years old woman with myasthenia gravis and recently occurred hyperthyroidism is presented in this study. Radioactive iodine therapy was applied to the patient and after 3 months of medication the patient become euthyroid and clinical findings of myasthenia were regressed.
References
- Drachman DB. Myasthenia gravis. N Engl J Med 1994;330:1797-810.
- Ratanakorn D, Vejjajiva A. Long-term follow-up of myasthenia gravis patients with hyperthyroidism. Acta Neurol Scand 2002;106(2):93-8.
- Marinó M, Ricciardi R, Pinchera A, Barbesino G, Manetti L, Chiovato L, Braverman LE, Rossi B, Muratorio A, Mariotti S.Mild clinical expression of myasthenia gravis associated with autoimmune thyroid diseases. J Clin Endocrinol Metab 1997; 82(2):438-43.
- Datt V, Tempe DK, Singh B, Tomar AS, Banerjee A, Dutta D, Bhandari H.Anesthetic management of patient with myasthenia gravis and uncontrolled hyperthyroidism for thymectomy. Ann Card Anaesth 2010;13(1):49-52.
- Trabelsi L, Charfi N, Triki Ch, Mnif M, Rekik N, Mhiri Ch, Abid M. Myasthenia gravis and hyperthyroidism: two cases. Ann Endocrinol (Paris) 2006;67(3):265-9.
- Moura-Neto A, Mosci C, Santos AO, Amorim BJ, de Lima MC, Etchebehere EC, Tambascia MA, Ramos CD, Zantut-Wittmann DE . Predictive factors of failure in a fixed 15 mCi 131I-iodide therapy for Graves’ disease. Clin Nucl Med 2012;37(6):550-4.
- Freedman S.Antisemitism and the history of myasthenia gravis. Isr Med Assoc J 2010;12(4):195-8
- Waller E.E, Razavi M, Picchi J. Myasthenia Gravis and Hyperthyroidism—A Report of Two Cases Calif Med 1963;99(5): 340–3.
- Weetman Ap. Graves’ Dis. N Engl J Med 2000;343: 1236–48.
- Knapska-Kucharska M, Oszukowska L, Lewiński A. Analysis of demographic and clinical factors affecting the outcome of radioiodine therapy in patients with hyperthyroidism Arch Med Sci 2010;6(4):611-6. 71
Abstract
Miyastenia gravis kas güçsüzlüğü ve yorgunlukla karakterize otoimmün bir hastalıktır. Myastenia gravis diğer otoimmun hastalıklar ile birlikte görülebilir. Miyastenia gravis hastalarında % 2-17.5 hipertiroidizm görülür. Hipertiroidizmin myastenia gravis klinik seyrini etkilediği bildirilmektedir. Bu vaka takdiminde miyastenia gravisi bulunan ve 3 ay önce hipertiroidi teşhisi konulan 27 yaşında bir bayan hasta sunulmuştur. Olguya, rad- yoaktif iyot tedavisi uygulanmış ve 3 ay sonra ötiroid olduğu ve miyestania şikâyetlerinin tedaviye daha iyi yanıt verdiği izlenmiştir.
References
- Drachman DB. Myasthenia gravis. N Engl J Med 1994;330:1797-810.
- Ratanakorn D, Vejjajiva A. Long-term follow-up of myasthenia gravis patients with hyperthyroidism. Acta Neurol Scand 2002;106(2):93-8.
- Marinó M, Ricciardi R, Pinchera A, Barbesino G, Manetti L, Chiovato L, Braverman LE, Rossi B, Muratorio A, Mariotti S.Mild clinical expression of myasthenia gravis associated with autoimmune thyroid diseases. J Clin Endocrinol Metab 1997; 82(2):438-43.
- Datt V, Tempe DK, Singh B, Tomar AS, Banerjee A, Dutta D, Bhandari H.Anesthetic management of patient with myasthenia gravis and uncontrolled hyperthyroidism for thymectomy. Ann Card Anaesth 2010;13(1):49-52.
- Trabelsi L, Charfi N, Triki Ch, Mnif M, Rekik N, Mhiri Ch, Abid M. Myasthenia gravis and hyperthyroidism: two cases. Ann Endocrinol (Paris) 2006;67(3):265-9.
- Moura-Neto A, Mosci C, Santos AO, Amorim BJ, de Lima MC, Etchebehere EC, Tambascia MA, Ramos CD, Zantut-Wittmann DE . Predictive factors of failure in a fixed 15 mCi 131I-iodide therapy for Graves’ disease. Clin Nucl Med 2012;37(6):550-4.
- Freedman S.Antisemitism and the history of myasthenia gravis. Isr Med Assoc J 2010;12(4):195-8
- Waller E.E, Razavi M, Picchi J. Myasthenia Gravis and Hyperthyroidism—A Report of Two Cases Calif Med 1963;99(5): 340–3.
- Weetman Ap. Graves’ Dis. N Engl J Med 2000;343: 1236–48.
- Knapska-Kucharska M, Oszukowska L, Lewiński A. Analysis of demographic and clinical factors affecting the outcome of radioiodine therapy in patients with hyperthyroidism Arch Med Sci 2010;6(4):611-6. 71
Details
| Primary Language | Turkish |
|---|---|
| Journal Section | Case Report |
| Authors | |
| Publication Date | September 1, 2013 |
| Published in Issue | Year 2013 Volume: 3 Issue: 3 |
