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Clinical Outcomes of Radioactive Iodine Therapy in a Patient with Myasthenia Gravis and Hyperthyroidism

Year 2013, Volume: 3 Issue: 3, 69 - 71, 01.09.2013

Abstract

Myasthenia Gravis is an autoimmune disease characterized with muscle weakness and fatigue. Hyperthyroidism can be present with Myasthenia Gravis with a rate of 2-17.5
%. It is known that hyperthyroidism affects the clinical course of myasthenia gravis. A
27 years old woman with myasthenia gravis and recently occurred hyperthyroidism is presented in this study. Radioactive iodine therapy was applied to the patient and after 3 months of medication the patient become euthyroid and clinical findings of myasthenia were regressed.

References

  • Drachman DB. Myasthenia gravis. N Engl J Med 1994;330:1797-810.
  • Ratanakorn D, Vejjajiva A. Long-term follow-up of myasthenia gravis patients with hyperthyroidism. Acta Neurol Scand 2002;106(2):93-8.
  • Marinó M, Ricciardi R, Pinchera A, Barbesino G, Manetti L, Chiovato L, Braverman LE, Rossi B, Muratorio A, Mariotti S.Mild clinical expression of myasthenia gravis associated with autoimmune thyroid diseases. J Clin Endocrinol Metab 1997; 82(2):438-43.
  • Datt V, Tempe DK, Singh B, Tomar AS, Banerjee A, Dutta D, Bhandari H.Anesthetic management of patient with myasthenia gravis and uncontrolled hyperthyroidism for thymectomy. Ann Card Anaesth 2010;13(1):49-52.
  • Trabelsi L, Charfi N, Triki Ch, Mnif M, Rekik N, Mhiri Ch, Abid M. Myasthenia gravis and hyperthyroidism: two cases. Ann Endocrinol (Paris) 2006;67(3):265-9.
  • Moura-Neto A, Mosci C, Santos AO, Amorim BJ, de Lima MC, Etchebehere EC, Tambascia MA, Ramos CD, Zantut-Wittmann DE . Predictive factors of failure in a fixed 15 mCi 131I-iodide therapy for Graves’ disease. Clin Nucl Med 2012;37(6):550-4.
  • Freedman S.Antisemitism and the history of myasthenia gravis. Isr Med Assoc J 2010;12(4):195-8
  • Waller E.E, Razavi M, Picchi J. Myasthenia Gravis and Hyperthyroidism—A Report of Two Cases Calif Med 1963;99(5): 340–3.
  • Weetman Ap. Graves’ Dis. N Engl J Med 2000;343: 1236–48.
  • Knapska-Kucharska M, Oszukowska L, Lewiński A. Analysis of demographic and clinical factors affecting the outcome of radioiodine therapy in patients with hyperthyroidism Arch Med Sci 2010;6(4):611-6. 71

MYASTHENİA GRAVİSLİ HİPERTİROİDİ HASTASINDA RADYOAKTİF İYOT TEDAVİSİNİN KLİNİK SONUÇLARI

Year 2013, Volume: 3 Issue: 3, 69 - 71, 01.09.2013

Abstract

Miyastenia gravis kas güçsüzlüğü ve yorgunlukla karakterize otoimmün bir hastalıktır. Myastenia gravis diğer otoimmun hastalıklar ile birlikte görülebilir. Miyastenia gravis hastalarında % 2-17.5 hipertiroidizm görülür. Hipertiroidizmin myastenia gravis klinik seyrini etkilediği bildirilmektedir. Bu vaka takdiminde miyastenia gravisi bulunan ve 3 ay önce hipertiroidi teşhisi konulan 27 yaşında bir bayan hasta sunulmuştur. Olguya, rad- yoaktif iyot tedavisi uygulanmış ve 3 ay sonra ötiroid olduğu ve miyestania şikâyetlerinin tedaviye daha iyi yanıt verdiği izlenmiştir.

References

  • Drachman DB. Myasthenia gravis. N Engl J Med 1994;330:1797-810.
  • Ratanakorn D, Vejjajiva A. Long-term follow-up of myasthenia gravis patients with hyperthyroidism. Acta Neurol Scand 2002;106(2):93-8.
  • Marinó M, Ricciardi R, Pinchera A, Barbesino G, Manetti L, Chiovato L, Braverman LE, Rossi B, Muratorio A, Mariotti S.Mild clinical expression of myasthenia gravis associated with autoimmune thyroid diseases. J Clin Endocrinol Metab 1997; 82(2):438-43.
  • Datt V, Tempe DK, Singh B, Tomar AS, Banerjee A, Dutta D, Bhandari H.Anesthetic management of patient with myasthenia gravis and uncontrolled hyperthyroidism for thymectomy. Ann Card Anaesth 2010;13(1):49-52.
  • Trabelsi L, Charfi N, Triki Ch, Mnif M, Rekik N, Mhiri Ch, Abid M. Myasthenia gravis and hyperthyroidism: two cases. Ann Endocrinol (Paris) 2006;67(3):265-9.
  • Moura-Neto A, Mosci C, Santos AO, Amorim BJ, de Lima MC, Etchebehere EC, Tambascia MA, Ramos CD, Zantut-Wittmann DE . Predictive factors of failure in a fixed 15 mCi 131I-iodide therapy for Graves’ disease. Clin Nucl Med 2012;37(6):550-4.
  • Freedman S.Antisemitism and the history of myasthenia gravis. Isr Med Assoc J 2010;12(4):195-8
  • Waller E.E, Razavi M, Picchi J. Myasthenia Gravis and Hyperthyroidism—A Report of Two Cases Calif Med 1963;99(5): 340–3.
  • Weetman Ap. Graves’ Dis. N Engl J Med 2000;343: 1236–48.
  • Knapska-Kucharska M, Oszukowska L, Lewiński A. Analysis of demographic and clinical factors affecting the outcome of radioiodine therapy in patients with hyperthyroidism Arch Med Sci 2010;6(4):611-6. 71
There are 10 citations in total.

Details

Primary Language Turkish
Journal Section Case Report
Authors

Füsun Aydoğan This is me

Akın Aydoğan This is me

Seçkin Akküçük This is me

İhsan Üstün This is me

Cumali Gökçe This is me

Mustafa Uğur This is me

Publication Date September 1, 2013
Published in Issue Year 2013 Volume: 3 Issue: 3

Cite

APA Aydoğan, F., Aydoğan, A., Akküçük, S., Üstün, İ., et al. (2013). MYASTHENİA GRAVİSLİ HİPERTİROİDİ HASTASINDA RADYOAKTİF İYOT TEDAVİSİNİN KLİNİK SONUÇLARI. Bozok Tıp Dergisi, 3(3), 69-71.
AMA Aydoğan F, Aydoğan A, Akküçük S, Üstün İ, Gökçe C, Uğur M. MYASTHENİA GRAVİSLİ HİPERTİROİDİ HASTASINDA RADYOAKTİF İYOT TEDAVİSİNİN KLİNİK SONUÇLARI. Bozok Tıp Dergisi. September 2013;3(3):69-71.
Chicago Aydoğan, Füsun, Akın Aydoğan, Seçkin Akküçük, İhsan Üstün, Cumali Gökçe, and Mustafa Uğur. “MYASTHENİA GRAVİSLİ HİPERTİROİDİ HASTASINDA RADYOAKTİF İYOT TEDAVİSİNİN KLİNİK SONUÇLARI”. Bozok Tıp Dergisi 3, no. 3 (September 2013): 69-71.
EndNote Aydoğan F, Aydoğan A, Akküçük S, Üstün İ, Gökçe C, Uğur M (September 1, 2013) MYASTHENİA GRAVİSLİ HİPERTİROİDİ HASTASINDA RADYOAKTİF İYOT TEDAVİSİNİN KLİNİK SONUÇLARI. Bozok Tıp Dergisi 3 3 69–71.
IEEE F. Aydoğan, A. Aydoğan, S. Akküçük, İ. Üstün, C. Gökçe, and M. Uğur, “MYASTHENİA GRAVİSLİ HİPERTİROİDİ HASTASINDA RADYOAKTİF İYOT TEDAVİSİNİN KLİNİK SONUÇLARI”, Bozok Tıp Dergisi, vol. 3, no. 3, pp. 69–71, 2013.
ISNAD Aydoğan, Füsun et al. “MYASTHENİA GRAVİSLİ HİPERTİROİDİ HASTASINDA RADYOAKTİF İYOT TEDAVİSİNİN KLİNİK SONUÇLARI”. Bozok Tıp Dergisi 3/3 (September 2013), 69-71.
JAMA Aydoğan F, Aydoğan A, Akküçük S, Üstün İ, Gökçe C, Uğur M. MYASTHENİA GRAVİSLİ HİPERTİROİDİ HASTASINDA RADYOAKTİF İYOT TEDAVİSİNİN KLİNİK SONUÇLARI. Bozok Tıp Dergisi. 2013;3:69–71.
MLA Aydoğan, Füsun et al. “MYASTHENİA GRAVİSLİ HİPERTİROİDİ HASTASINDA RADYOAKTİF İYOT TEDAVİSİNİN KLİNİK SONUÇLARI”. Bozok Tıp Dergisi, vol. 3, no. 3, 2013, pp. 69-71.
Vancouver Aydoğan F, Aydoğan A, Akküçük S, Üstün İ, Gökçe C, Uğur M. MYASTHENİA GRAVİSLİ HİPERTİROİDİ HASTASINDA RADYOAKTİF İYOT TEDAVİSİNİN KLİNİK SONUÇLARI. Bozok Tıp Dergisi. 2013;3(3):69-71.
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