SPONTAN ABORTUSLARIN MEVSİMSEL DAĞILIMLARININ İNCELENMESİ An Investigation on the Seasonal Distribution of Spontaneous Abortus
Abstract
ÖZET
Amaç: Abortus etiyolojisinin anlaşılması istenen gebelik kayıplarının önlenmesi açısından önemlidir. Dünyada
Kanada, Avusturalya gibi bazı ülkelerde abortusların mevsimsel dağılım gösterdiğini bildiren yayınlar mevcuttur,
ancak ülkemizde bu konu ile ilgili veri bulunmamaktadır. Bu çalışmanın amacı bölgemizde spontan abortusların
mevsimsel dağılımlarının değerlendirilmesidir.
Gereç ve Yöntemler: Yapılan çalışmada, 1 Ocak 2015 ile 1 Ocak 2018 tarihleri arasında hastanemize başvuran,
20-49 yaş arasındaki 707 gebenin demografik verileri retrospektif olarak analiz edildi. Tüm abortus olgularının
ve alt türlerinin mevsimlere göre dağılımları ki-kare testi ile analiz edildi. Çalışma, IBM SPSS (Sosyal Bilimler
İçin İstatistik Programı) 22 programı ortamında analiz edildi. Veriler α=0.05 yanılma düzeyi ve %95 güven
aralığında değerlendirildi.
Bulgular: Çalışmada abortus olan gebelerin yaş ortalaması 34±6 idi. Abortusların (n=707) mevsimlere
göre dağılımı incelendiğinde kış mevsiminde %26,2 (n=185), ilkbaharda %25,5 (n=180), yaz mevsiminde
%23,1(n=163), sonbaharda ise %22,8 (n=179) oranında olduğu görüldü. Yapılan tek örneklem ki-kare
testine göre, abortusların mevsimlere göre dağılımları incelendiğinde mevsimler arasında istatistiksel olarak
anlamlı farklılık bulunmadı (p=0.672). Abortus türlerinin, mevsimlere göre dağılımları incelendiğinde missed
abortusların ilkbahar mevsiminde daha sık olduğu görüldü (p=0.00072) ve istatistiksel olarak anlamlı farklılık
bulundu (p<0.001). Kimyasal gebeliklerin ise kış mevsiminde daha fazla olduğu görüldü ve bu fark istatistiksel
olarak anlamlı bulundu (p=0.003732). Ayrıca abortus incipienceler yaz mevsiminde daha çok görüldü ve bu
fark istatistiksel olarak anlamlı bulundu (p=0.00019).
Sonuç: Abortusların mevsimlere göre dağılımı incelendiğinde mevsimler arasında istatistiksel olarak anlamlı
farklılık bulunmadı. Ancak missed abortusların ilkbahar mevsiminde (polen mevsimi olduğundan) daha sık
görülmesi nedeni ile missed abortus etiyolojisinde immünolojik faktörlerin önemli olabileceğini düşünüldü.
Anahtar Kelimeler: Spontan abortus; Mevsimsel dağılım; Missed abortus
ABSTRACT
Objective: Understanding the etiology of an abortus is significant in terms of prevention of the desired
pregnancy losses. There are a number of worlwide publications regarding the role of seasons among these
environmental factors in some countries such as Canada and Australia, however, there is no data on this
subject in our country. The purpose of this study is evaluating the seasonal distribution of spontaneous
abortus in our region.
Material and Methods: In this study, the demographic data of 707 pregnant women aged between 20-
49 applied to our hospital between the dates of January 1st 2015 and 1st January 2018 were analyzed
retrospectively. The seasonal distribution of abortus cases was examined. Chi-square test was used for the
analysis of seasonal distrubition of all abortus and sub-species. The data obtained in this study was analyzed
via IBM SPSS (Statistical Package for the Social Sciences) 22. The data were estimated at α = 0.05 error level
and 95% confidence interval.
Results: The mean age of the pregnant women with abortus was 34 ± 6 years. When the distribution of abortus
(n=707) was examined, it was seen that in winter 26, 2% (n=185), in spring 25, 5% (n =180), in summer), 23,
1% (n =163), in autumn 22,8 (n = 179). According to the single sample chi-square test, when the seasonal
distribution of abortuss types were examined, no statistically significant difference was found between the
seasons (p = 0.672). When the distribution of abortus sub-species according to seasons were examined, it
was seen that the missed abortus were more frequent in spring (p = 0.00072) and a statistically significant
difference was found (p <0.001). The chemical pregnancies were more common in winter and this difference
was statistically significant (p = 0.003732). In addition, abortus incipiens were more common in summer and
this difference was statistically significant (p = 0.00019).
Conclucions: When the distribution of abortuss was evaluated according to seasons, there was found no
statistically significant differences between seasons.It was found out that the missed abortus frequently
occured in the spring season, accordingly, it is suggested that immunological factors (in connection with the
pollen season) might be considered significant in the etiology of an abortus.
Keywords: Spontan abortus; Seasonal distribution; Missed abortus
References
- 1. Wilcox AJ, Weinberg CR, O'Connor JF, Baird DD, Schlatterer JP, Canfield RE.et al. Incidence of early loss of pregnancy. N Engl J Med. 1988;319(4):189-94. 2. Hacettepe Üniversitesi Nüfus Etütleri Enstitüsü, T.C. Kalkınma Bakanlığı ve Tübitak, Ankara Türkiye. 2013 Türkiye Nüfus ve Sağlık Araştırması. 2014. Yayın No: NEE-HÜ.14.01 ISBN 978-975-491-390-3. 3. Caroline E, O’ Brien O and K. Guidelines on the diagnosis and management of abortus. Farquharson RG, Stephenson MD. Early pregnancy. 1st ed. New York: Cambridge University Press. 2010. P.129. 4. Cunningham FG, Leveno KJ, Bloom SL, Hauth JC, Rouse DJ, Spong CY. Ectopic Pregnancy. Twicker DM, Wendel GD. Williams Obstetrics. 22nd ed, Dallas, Texas, McGraw Hill Professional, 2005, p.239-240. 5. Stern JJ, Dorfmann AD, Gutierrez-Najar AJ, Cerrillo M, Coulam CB. Frequency of abnormal karyotypes among abortus from women with and without a history of recurrent spontaneous abortion. Fertil Steril. 1996; 65(2):250–253. 6. Bourne T, Bottomley C. When is a pregnancy nonviable and what criteria should be used to define abortus? Fertil Steril. 2012;98(5):1091-6. 7. Lane BF, Wong-You-Cheong JJ, Javitt MC, Glanc P, Brown DL, et al. ACR appropriateness Criteria, first trimester bleeding. Ultrasound Q. 2013; 29(2):91-6. 8. Bromley B, Harlow BL, Laboda LA, Benacerraf BR. Small sac size in the first trimester: a predictor of poor fetal outcome. Radiology. 1991;178(2):375-7. 9. Acharya G, Morgan H. First-trimester, three-dimensional transvaginal ultrasound volumetry in normal pregnancies and spontaneous abortuss. Ultrasound Obstet Gynecol. 2002;19(6):575-9. 10. Barnhart KT. Clinical practice. Ectopic pregnancy. N Engl J Med. 2009;361(4):379-87.
Abstract
References
- 1. Wilcox AJ, Weinberg CR, O'Connor JF, Baird DD, Schlatterer JP, Canfield RE.et al. Incidence of early loss of pregnancy. N Engl J Med. 1988;319(4):189-94. 2. Hacettepe Üniversitesi Nüfus Etütleri Enstitüsü, T.C. Kalkınma Bakanlığı ve Tübitak, Ankara Türkiye. 2013 Türkiye Nüfus ve Sağlık Araştırması. 2014. Yayın No: NEE-HÜ.14.01 ISBN 978-975-491-390-3. 3. Caroline E, O’ Brien O and K. Guidelines on the diagnosis and management of abortus. Farquharson RG, Stephenson MD. Early pregnancy. 1st ed. New York: Cambridge University Press. 2010. P.129. 4. Cunningham FG, Leveno KJ, Bloom SL, Hauth JC, Rouse DJ, Spong CY. Ectopic Pregnancy. Twicker DM, Wendel GD. Williams Obstetrics. 22nd ed, Dallas, Texas, McGraw Hill Professional, 2005, p.239-240. 5. Stern JJ, Dorfmann AD, Gutierrez-Najar AJ, Cerrillo M, Coulam CB. Frequency of abnormal karyotypes among abortus from women with and without a history of recurrent spontaneous abortion. Fertil Steril. 1996; 65(2):250–253. 6. Bourne T, Bottomley C. When is a pregnancy nonviable and what criteria should be used to define abortus? Fertil Steril. 2012;98(5):1091-6. 7. Lane BF, Wong-You-Cheong JJ, Javitt MC, Glanc P, Brown DL, et al. ACR appropriateness Criteria, first trimester bleeding. Ultrasound Q. 2013; 29(2):91-6. 8. Bromley B, Harlow BL, Laboda LA, Benacerraf BR. Small sac size in the first trimester: a predictor of poor fetal outcome. Radiology. 1991;178(2):375-7. 9. Acharya G, Morgan H. First-trimester, three-dimensional transvaginal ultrasound volumetry in normal pregnancies and spontaneous abortuss. Ultrasound Obstet Gynecol. 2002;19(6):575-9. 10. Barnhart KT. Clinical practice. Ectopic pregnancy. N Engl J Med. 2009;361(4):379-87.
Details
| Primary Language | Turkish |
|---|---|
| Subjects | Health Care Administration |
| Journal Section | Original Research |
| Authors | |
| Publication Date | March 25, 2020 |
| Published in Issue | Year 2020 Volume: 10 Issue: 1 |