ÇOCUKLARDA D VİTAMİNİ EKSİKLİĞİNİN ÜRİNER İNKONTİNANS ÜZERİNE ETKİLERİ The Effects of Vitamin D Deficiency on Urinary Incontinence in Children
Abstract
ÖZET
Amaç: D vitamini, kalsiyum metabolizmasındaki rolü ile en belirgin etkisi kas iskelet sistemi üzerine olan yağda
eriyen bir vitamindir. Bu durum, klinikte pelvik taban kasları üzerine etkileri ile idrar ve gaita yapma mekanizmalarında
da etkili olacağı hipotezini düşündürmektedir. Çalışmamız çocuklarda D vitamini eksikliği ile üriner
inkontinans (Üİ) arasında ilişkiyi araştırmak amacıyla yapılmıştır.
Gereç ve yöntem: D vitamini eksikliği olan çocuklarda Üİ araştırıldığı bir anket çalışması yapılmıştır. Çocuk
polikliniklerine başvuran D vitamini düzeyi 30 ng/dl altında, 5 yaş üzerinde, rastgele seçilmiş 100 hasta değerlendirmeye
alınmıştır. Üİ, kabızlık ve enkoprezis sorgulanmıştır.
Bulgular: Yaş ortalaması 10.1(5-16) yıl olan 53 kız, 47 erkek çocuk değerlendirildi. D vitamini düzeyi ortalama
15.42 (4.7-26.36) ng/dl bulundu. D vitamini eksikliği olan çocuklarda Üİ %20, kabızlık %31, enkoprezis %3 tespit
edildi. Toplamda 100 hastanın %40‘ında bu semptomlardan bir ya da birkaçı mevcuttu.
Sonuç: D vitamini eksikliği olan çocuklarda Üİ ile ilişki görülmüştür. Çocuklarda Üİ patogenez ve tedavisinde D
vitamini ile ilgili ileri çalışmalara ihtiyaç vardır.
Anahtar kelimeler: Üriner inkontinans; D vitamini eksikliği; Çocuk
ABSTRACT
Objective: Vitamin D is a fat-soluble vitamin that most significant effect on the musculoskeletal system by its
calcium metabolism role. This suggests that it will be effective in urinary and fecal continence mechanisms
with its effects on pelvic floor muscles. Our study was conducted to investigate the relationship between
vitamin D deficiency and urinary incontinence (UI) in children.
Materials and method: A survey was conducted to investigate UI in children with vitamin D deficiency. 100
randomly selected patients over 5 years of age with vitamin D levels below 30 ng / dl were included in the
study. UI, constipation and encopresis were questioned.
Results: Fiftythree girls and 47 boys with a mean age of 10.1 (5-16) years were evaluated. The mean vitamin
D level was found to be 15.42 (4.7-26.36) ng / dl. UI was found to be 20%, constipation 31% and encopresis
3% in children with vitamin D deficiency. In total, 40% of 100 patients had one or more of these symptoms
Conclusion: In our study, we found that an association between vitamin D deficiency and UI in children.
Further studies on vitamin D in the pathogenesis and treatment of UI in children are needed.
Key words: Urinary incontinence; Vitamin D deficiency; Children
References
- 1. Badalian SS, Rosenbaum PF. Vitamin D and pelvic floor disorders in women: results from the National Health and Nutrition Examination Survey. Obstet Gynecol. 2010;115:795–803. 2. Bischoff HA, Borchers M, Gudat F, Duermueller U, Theiler R, Sta¨helin HB, et al. In situ detection of the 1,25-dihydroxyvita-min D3 receptor in human skeletal muscle tissue. Histochem J. 2001;33:19 –24. 3. Crescioli C, Morelli A, Adorini L, Feruzzi P, Luconi M, Vannelli GB, et al. Human bladder as a novel target for vitamin D receptor ligands. J Clin Endocrinol Metab. 2005;90:962–72. 4. Schro¨ der A, Colli E, Maggi M, Andersson KE. Effects of vitamin D(3) analogue in a rat model of bladder outlet obstruction. BJU Int. 2006;98:637– 42. 5. Elshazly MA, Sultan MF, Aboutaleb HA, Salem SM, Aziz MS, Abd Elbaky TM et al. Vitamin D deficiency and lower urinary tract symptoms in males above 50 years of age. Urol Ann. 2017;9 (2): 170-173. 6. Haid B, Tekgül S. Primary and Secondary Enuresis: Pathophysiology, Diagnosis, and Treatment. Eur Urol Focus. 2017;3 (2-3):198-206. 7. Austin PF, Bauer SB, Bower W, Chase J, Franco I, Hoebeke P, et al. The standardization of terminology of lower urinary tract function in children and adolescents: update report from the Standardization Committee of the International Children's Continence Society. J Urol. 2014 Jun;191(6):1863-1865.e13 8. McGrath KH, Caldwell PHY, Jones MP. The frequency of constipation in children with nocturnal enuresis: A comparison with parental reporting. J Paediatr Child Health. 2008;44:19–27. 9. Dallosso HM, McGrother CW, Matthews RJ, Donaldson MM; Leicestershire MRC Incontinence Study Group. Nutrient composition of the diet and the development of overactive bladder: a longitudinal study in women. Neurourol Urodyn. 2004;23(3):204–10. 10. Parker-Autry CY, Burgio KL, Richter HE. Vitamin D status: a review with implications for the pelvic floor. Int Urogynecol J. 2012;23(11):1517–26.
Abstract
References
- 1. Badalian SS, Rosenbaum PF. Vitamin D and pelvic floor disorders in women: results from the National Health and Nutrition Examination Survey. Obstet Gynecol. 2010;115:795–803. 2. Bischoff HA, Borchers M, Gudat F, Duermueller U, Theiler R, Sta¨helin HB, et al. In situ detection of the 1,25-dihydroxyvita-min D3 receptor in human skeletal muscle tissue. Histochem J. 2001;33:19 –24. 3. Crescioli C, Morelli A, Adorini L, Feruzzi P, Luconi M, Vannelli GB, et al. Human bladder as a novel target for vitamin D receptor ligands. J Clin Endocrinol Metab. 2005;90:962–72. 4. Schro¨ der A, Colli E, Maggi M, Andersson KE. Effects of vitamin D(3) analogue in a rat model of bladder outlet obstruction. BJU Int. 2006;98:637– 42. 5. Elshazly MA, Sultan MF, Aboutaleb HA, Salem SM, Aziz MS, Abd Elbaky TM et al. Vitamin D deficiency and lower urinary tract symptoms in males above 50 years of age. Urol Ann. 2017;9 (2): 170-173. 6. Haid B, Tekgül S. Primary and Secondary Enuresis: Pathophysiology, Diagnosis, and Treatment. Eur Urol Focus. 2017;3 (2-3):198-206. 7. Austin PF, Bauer SB, Bower W, Chase J, Franco I, Hoebeke P, et al. The standardization of terminology of lower urinary tract function in children and adolescents: update report from the Standardization Committee of the International Children's Continence Society. J Urol. 2014 Jun;191(6):1863-1865.e13 8. McGrath KH, Caldwell PHY, Jones MP. The frequency of constipation in children with nocturnal enuresis: A comparison with parental reporting. J Paediatr Child Health. 2008;44:19–27. 9. Dallosso HM, McGrother CW, Matthews RJ, Donaldson MM; Leicestershire MRC Incontinence Study Group. Nutrient composition of the diet and the development of overactive bladder: a longitudinal study in women. Neurourol Urodyn. 2004;23(3):204–10. 10. Parker-Autry CY, Burgio KL, Richter HE. Vitamin D status: a review with implications for the pelvic floor. Int Urogynecol J. 2012;23(11):1517–26.
Details
| Primary Language | Turkish |
|---|---|
| Subjects | Health Care Administration |
| Journal Section | Original Research |
| Authors | |
| Publication Date | March 25, 2020 |
| Published in Issue | Year 2020 Volume: 10 Issue: 1 |