İMMUNGLOBULİN A VASKÜLİTİ TANILI ÇOCUK HASTALARDA SKROTAL TUTULUM: TEK MERKEZ DENEYİMİ Scrotal Involvement in Pediatric Patients With Immunoglobulin A Vasculitis: A Single-Center Experience
Abstract
Amaç: Bu çalışmada skrotal tutulumu olan immunglobulin A (IgA) vasküliti tanısı alan çocuk hastaların değerlendirilmesi
amaçlandı.
Gereç ve Yöntemler: 1 Mart 2019- 1 Ekim 2022 tarihleri arasında IgA vasküliti tanısı alan, skrotal tutulumu olan
hastaların klinik ve demografik özellikleri, skrotal tutulumu olmayan hastaların özellikleriyle karşılaştırıldı.
Bulgular: 159 erkek hastanın 15 (%9,5)’inde skrotal tutulum saptandı. Skrotal tutulumu olan hastaların
skrotal tutulumu olmayanlara göre tanı yaşı daha küçüktü. Skrotal tutulumu olmayanlarda gastrointestinal
tutulum daha yüksek saptandı. Hastaların %60’ında bilateral skrotal tutulum görüldü. Skrotal tutulumu
olan hastaların yaklaşık dörtte üçü steroid tedavisi aldı. Hiçbir hastada relaps ve komplikasyon görülmedi.
Sonuç: IgA vasküliti seyrinde skrotal tutulum varlığında hastaların tedavi ve izlemi değişebileceği için IgA
vasküliti tanısı alan erkek hastalarda skrotum muayenesi mutlaka yapılmalı ve ihmal edilmemelidir.
Keywords
İMMUNGLOBULİN A VASKÜLİTİ TANILI ÇOCUK HASTALARDA SKROTAL TUTULUM: TEK MERKEZ DENEYİMİ Scrotal Involvement in Pediatric Patients With Immunoglobulin A Vasculitis: A Single-Center Experience
References
- 1. Ozen S, Marks SD, Brogan P, Groot N, de Graeff N, Avcin T, et al. European consensus-based recommendations for diagnosis and treatment of immunoglobulin A vasculitis-the SHARE initiative. Rheumatology (Oxford). 2019;58(9):1607-16.
- 2. Ozen S, Pistorio A, Iusan SM, Bakkaloglu A, Herlin T, Brik R, et al. Paediatric Rheumatology International Trials Organisation (PRINTO). EULAR/PRINTO/PRES criteria for Henoch-Schönlein purpura, childhood polyarteritis nodosa, childhood Wegener granulomatosis and childhood Takayasu arteritis: Ankara 2008. Part II: Final classification criteria. Ann Rheum Dis 2010;69(5):798-806.
- 3. Du L, Wang P, Liu C, Li S, Yue S, Yang Y. Multisystemic manifestations of IgA vasculitis. Clin Rheumatol 2021;40(1):43-52.
- 4. Sunar Yayla EN, Bakkalolu SA. Clinical features of paediatric immunoglobulin A vasculitis patients with scrotal involvement. Mod Rheumatol. 2023 Aug 25;33(5): 1016-20
- 5. Kaya Akca U, Batu ED, Serin O, Ipek OF, Aydin O, Teksam O, et al. Penile involvement of immunoglobulin a vasculitis/Henoch-Schönlein purpura. J Pediatr Urol. 2021;17(3):409.e1-8.
- 6. Di Pietro GM, Castellazzi ML, Mastrangelo A, Montini G, Marchisio P, Tagliabue C. Henoch-Schönlein Purpura in children: not only kidney but also lung. Pediatr Rheumatol Online J. 2019;17(1):75.
- 7. Modi S, Mohan M, Jennings A. Acute Scrotal Swelling in Henoch-Schonlein Purpura: Case Report and Review of the Literature. Urol Case Rep. 2016;6:9-11.
- 8. Ha TS, Lee JS. Scrotal involvement in childhood Henoch- Scḧonlein purpura. Acta Paediatr 2007;96:552–5.
- 9. Buscatti IM, Abrão HM, Kozu K, Marques VLS, Gomes RC, Sallum AME, et al. Characterization of scrotal involvement in children and adolescents with IgA vasculitis. Adv Rheumatol 2018;58:38.
- 10. Ben-Sira L, Laor T. Severe scrotal pain in boys with Henoch-Schönlein purpura: incidence and sonography. Pediatr Radiol. 2000;30(2):125-8.
Abstract
References
- 1. Ozen S, Marks SD, Brogan P, Groot N, de Graeff N, Avcin T, et al. European consensus-based recommendations for diagnosis and treatment of immunoglobulin A vasculitis-the SHARE initiative. Rheumatology (Oxford). 2019;58(9):1607-16.
- 2. Ozen S, Pistorio A, Iusan SM, Bakkaloglu A, Herlin T, Brik R, et al. Paediatric Rheumatology International Trials Organisation (PRINTO). EULAR/PRINTO/PRES criteria for Henoch-Schönlein purpura, childhood polyarteritis nodosa, childhood Wegener granulomatosis and childhood Takayasu arteritis: Ankara 2008. Part II: Final classification criteria. Ann Rheum Dis 2010;69(5):798-806.
- 3. Du L, Wang P, Liu C, Li S, Yue S, Yang Y. Multisystemic manifestations of IgA vasculitis. Clin Rheumatol 2021;40(1):43-52.
- 4. Sunar Yayla EN, Bakkalolu SA. Clinical features of paediatric immunoglobulin A vasculitis patients with scrotal involvement. Mod Rheumatol. 2023 Aug 25;33(5): 1016-20
- 5. Kaya Akca U, Batu ED, Serin O, Ipek OF, Aydin O, Teksam O, et al. Penile involvement of immunoglobulin a vasculitis/Henoch-Schönlein purpura. J Pediatr Urol. 2021;17(3):409.e1-8.
- 6. Di Pietro GM, Castellazzi ML, Mastrangelo A, Montini G, Marchisio P, Tagliabue C. Henoch-Schönlein Purpura in children: not only kidney but also lung. Pediatr Rheumatol Online J. 2019;17(1):75.
- 7. Modi S, Mohan M, Jennings A. Acute Scrotal Swelling in Henoch-Schonlein Purpura: Case Report and Review of the Literature. Urol Case Rep. 2016;6:9-11.
- 8. Ha TS, Lee JS. Scrotal involvement in childhood Henoch- Scḧonlein purpura. Acta Paediatr 2007;96:552–5.
- 9. Buscatti IM, Abrão HM, Kozu K, Marques VLS, Gomes RC, Sallum AME, et al. Characterization of scrotal involvement in children and adolescents with IgA vasculitis. Adv Rheumatol 2018;58:38.
- 10. Ben-Sira L, Laor T. Severe scrotal pain in boys with Henoch-Schönlein purpura: incidence and sonography. Pediatr Radiol. 2000;30(2):125-8.
Details
| Primary Language | Turkish |
|---|---|
| Subjects | Pediatric Rheumatology |
| Journal Section | Original Research |
| Authors | |
| Publication Date | June 14, 2024 |
| Submission Date | June 1, 2024 |
| Acceptance Date | June 2, 2024 |
| Published in Issue | Year 2024 Volume: 14 Issue: 2 |
