Year 2019, Volume 2 , Issue 3, Pages 60 - 64 2019-09-01

Brucellosis: A Retrospective Evaluation of 170 Cases

Havva Tunay [1] , Nese Demirturk [2] , Petek Sarlak Konya [3] , Serap Pamukcuoglu [4]


Brucellosis is an important disease with devastating outcomes in developing countries and may cause complications in many organ systems. The clinical and laboratory characteristics of 170 cases of brucellosis followed at the Afyon Kocatepe University Faculty of Medicine Infectious Diseases Clinic and Afyonkarahisar State Hospital of Medicine Infectious Diseases Clinic in Turkey, were retrospectively evaluated. In our study, total of 170 patients (female, n=74; 43.5%, and male, n=96; 56.5%) with a mean age of 44.12 ± 15.52 years were included. The patients were living in rural areas (n=134; 78.8%) or in the city center (n=36; 21.2%), while 112 (65.9%) patients were raising livestock and 84 patients (49.4%) were consumers of unpasteurized raw milk and dairy products. The most frequent complaints detected in patients with brucellosis include joint pain, fever, weakness, back pain and gastrointestinal symptoms. Fever, arthritis and scrotal swelling were observed more frequently than the others. The standard tube agglutination titer was > 1/160 in 150 (88.2%) patients. Blood cultures have positive results in 68 (59.6%) patients. Complications were detected in 45 patients (26.4%). Osteoarticular system involvement was the most common complication in 33 (19.4%) patients. Other complications were epididymo-orchitis in 9 (5.3%) and depression in 3 (1.8%) patients (Table 2). Sacroileitis was the most frequent osteoarticular involvement which was detected in 13 (7.6%) patients. Other osteoarticular involvements were peripheral monoarthritis in 11 (6.5%), and spondylodiscitis in 9 (5.3%) patients. Increased C-reactive protein (CRP) and high serum transaminase levels were significantly higher in the complication groups. The most frequent drug treatment was rifampicin and doxycyline among different treatment regimens. Brucellosis should be considered in the differential diagnosis of patients who present with fever and osteoarticular symptoms. Laboratory results can help the clinician to identify the complications of this disease, especially osteoarticular complications.

Brucellosis, Epidemiology, Clinical finding, Laboratory finding
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Primary Language en
Subjects General and Internal Medicine
Journal Section Articles
Authors

Orcid: 0000-0003-4333-582X
Author: Havva Tunay (Primary Author)
Institution: TIP FAKÜLTESİ
Country: Turkey


Orcid: 0000-0002-6186-2494
Author: Nese Demirturk
Institution: TIP FAKÜLTESİ
Country: Turkey


Orcid: 0000-0001-5055-1220
Author: Petek Sarlak Konya
Institution: AFYONKARAHİSAR DEVLET HASTANESİ
Country: Turkey


Orcid: 0000-0001-5090-2510
Author: Serap Pamukcuoglu
Institution: AFYONKARAHİSAR DEVLET HASTANESİ
Country: Turkey


Dates

Publication Date : September 1, 2019

Bibtex @research article { bshealthscience547695, journal = {Black Sea Journal of Health Science}, issn = {}, eissn = {2619-9041}, address = {bsjhealthsci@blackseapublishers.com}, publisher = {Cem TIRINK}, year = {2019}, volume = {2}, pages = {60 - 64}, doi = {}, title = {Brucellosis: A Retrospective Evaluation of 170 Cases}, key = {cite}, author = {Tunay, Havva and Demirturk, Nese and Sarlak Konya, Petek and Pamukcuoglu, Serap} }
APA Tunay, H , Demirturk, N , Sarlak Konya, P , Pamukcuoglu, S . (2019). Brucellosis: A Retrospective Evaluation of 170 Cases. Black Sea Journal of Health Science , 2 (3) , 60-64 . Retrieved from https://dergipark.org.tr/en/pub/bshealthscience/issue/46447/547695
MLA Tunay, H , Demirturk, N , Sarlak Konya, P , Pamukcuoglu, S . "Brucellosis: A Retrospective Evaluation of 170 Cases". Black Sea Journal of Health Science 2 (2019 ): 60-64 <https://dergipark.org.tr/en/pub/bshealthscience/issue/46447/547695>
Chicago Tunay, H , Demirturk, N , Sarlak Konya, P , Pamukcuoglu, S . "Brucellosis: A Retrospective Evaluation of 170 Cases". Black Sea Journal of Health Science 2 (2019 ): 60-64
RIS TY - JOUR T1 - Brucellosis: A Retrospective Evaluation of 170 Cases AU - Havva Tunay , Nese Demirturk , Petek Sarlak Konya , Serap Pamukcuoglu Y1 - 2019 PY - 2019 N1 - DO - T2 - Black Sea Journal of Health Science JF - Journal JO - JOR SP - 60 EP - 64 VL - 2 IS - 3 SN - -2619-9041 M3 - UR - Y2 - 2019 ER -
EndNote %0 Black Sea Journal of Health Science Brucellosis: A Retrospective Evaluation of 170 Cases %A Havva Tunay , Nese Demirturk , Petek Sarlak Konya , Serap Pamukcuoglu %T Brucellosis: A Retrospective Evaluation of 170 Cases %D 2019 %J Black Sea Journal of Health Science %P -2619-9041 %V 2 %N 3 %R %U
ISNAD Tunay, Havva , Demirturk, Nese , Sarlak Konya, Petek , Pamukcuoglu, Serap . "Brucellosis: A Retrospective Evaluation of 170 Cases". Black Sea Journal of Health Science 2 / 3 (September 2019): 60-64 .
AMA Tunay H , Demirturk N , Sarlak Konya P , Pamukcuoglu S . Brucellosis: A Retrospective Evaluation of 170 Cases. BSJ Health Sci.. 2019; 2(3): 60-64.
Vancouver Tunay H , Demirturk N , Sarlak Konya P , Pamukcuoglu S . Brucellosis: A Retrospective Evaluation of 170 Cases. Black Sea Journal of Health Science. 2019; 2(3): 64-60.