cujse Cankaya University Journal of Science and Engineering 2564-7954 Cankaya University Engineering Mühendislik Renal İskemi-Reperfüzyonu Sırasında Sıçan Böbreğinde Oluşan Oksidatif Stres Hasarına Silimarin Etkisi Şentürk Hakan Kolankaya Dürdane Şahin Yalçın 02 01 2010 7 1 05 13 2010 Copyright © 2009, Cankaya University Journal of Science and Engineering 2009 Cankaya University Journal of Science and Engineering

Renal ischemia reperfusion injury is the most common causes of acute renalfailure. Silybum marianum L. Gaertn. (milk thistle) is a plant which belongs to Asteraceaefamily. Silymarin is a plant derived flavonoid which is extracted from the seeds of the S.marianum L. In this study, we investigated the protective effect of silymarin during theexperimental renal ischemia reperfusion injury in rats histologically and biochemically.

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