LC-MS/MS Analysis and Biological Activities of Methanol Extract from Sagina apetala Ard.

Year 2023, Volume: 19 Issue: 3, 231 - 235, 30.09.2023

Rabia Nur Ün

https://doi.org/10.18466/cbayarfbe.1264511

Abstract

This is the first study on the investigation of phenolic compounds of methanol extract (ME) of Sagina apetala and examination of its cell-based antioxidant and antibacterial activity against Staphylococcus aureus and Pseudomonas aeruginosa. The determination of phenolic compounds of ME was performed by LC-MS/MS and 25 main compounds were identified. For the cell-based antioxidant activity of ME, Vero cell line (Cercopithecus aethiops kidney epithelial, Monolayer) was used as the model cell line and ME was showed 61.22% cell viability. ME, also showed insignificant antibacterial activity against both gram-positive and gram-negative bacteria. In conclusion, this study in the species provides the basic data for future studies for the species.

Keywords

Sagina apetala Ard, Phenolic compounds, Antioxidant activity, Antibacterial activity

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