Resveratrol Desteği Akut Yüzme Egzersizi Yaptırılan Sıçanların Bazı Dokularında Element Metabolizmasıyla İlişkilidir

Year 2023, Volume: 18 Issue: 2, 399 - 410, 31.12.2023

Abdulkerim Kasım Baltacı , Dilek Arslangil , Saltuk Buğra Baltacı , Rasim Moğulkoç , Ömer Ünal

https://doi.org/10.33459/cbubesbd.1261924

Abstract

Bu çalışmanın amacı, akut yüzme egzersizi yaptırılan sıçanlarda resveratrol uygulamasının bazı dokulardaki element metabolizmasını nasıl etkilediğini araştırmaktır. Wistar cinsi 28 adet erişkin erkek sıçan kullanılan araştırmada hayvanlar eşit sayıda 4 gruba ayrıldı. Grup 1, Kontrol; Grup 2, Yüzme: Standart diyetle beslenen ve 30 dakika akut yüzme egzersizi yaptırılan grup. Grup 3, Resveratrol: Dört hafta boyunca 10 mg/kg resveratrol desteği alan grup. Grup 4, Resveratrol + Yüzme: Dört hafta boyunca 10 mg/kg resveratrol desteği alan ve 30 dakika akut yüzme egzersizi yaptırılan grup. Dört haftalık diyet uygulamalarının bitiminde grup 2 ve grup 4 hayvanlarına 30 dakika akut yüzme egzersizi yaptırıldı. Yüzme uygulamalarından hemen sonra hayvanlar sakrifiye edilerek testis, böbrek, kalp ve karaciğer doku örnekleri alındı. Alınan doku örneklerinde element analizleri atomik emisyon yöntemiyle tayin edildi. Testis dokusundaki ölçümü yapılan elementler egzersiz ve resveratrol uygulamalarından etkilenmedi. Hem resveratrol uygulaması hem de akut yüzme egzersizi böbrek dokusunda çinko, demir, magnezyum, selenyum, molibden, kalp dokusunda demir, kalsiyum ve karaciğer dokusunda ise çinko, demir, molibden seviyelerinde değişikle sonuçlandı (p<0.05). Resveratrol uygulamasının hem egzersizde, hem de egzersizden bağımsız olarak sıçanların bazı dokularında element metabolizmasında değişikliklere yol açtığını ortaya koyan çalışmamızın bulguları med-line taramalardan yola çıkarak ilk ve orijinal bulgu olarak takdim edilebilir.

Keywords

Akut yüzme egzersizi, Element metabolizması, Resveratrol uygulaması, Rat

Project Number

SUBAPK; project no. 1420132013

Resveratrol Supplementation is Associated with Elemental Metabolism in Some Tissues of Acute Swimming Rats

Abstract

The aim of this study was to investigate how resveratrol administration affects element metabolism in some tissues in rats undergoing acute swimming exercise. In the study, 28 adult male Wistar rats were used and the animals were divided into 4 groups in equal numbers. Group 1, Control; Group 2, Swimming: The group fed a standard diet and had 30 minutes of acute swimming exercise. Group 3, Resveratrol: The group receiving 10 mg/kg resveratrol supplement for four weeks. Group 4, Resveratrol + Swimming: The group that received 10 mg/kg resveratrol supplement for four weeks and also had 30 minutes of acute swimming exercise. At the end of the four-weeks diet, group 2 and group 4 animals were given 30 minutes of acute swimming exercise. Animals were sacrificed immediately after swimming practices, and testis, kidney, heart and liver tissue samples were taken. Elemental analyzes in tissue samples were determined by atomic emission method. Elements measured in testicular tissue were not affected by exercise and resveratrol applications. Both resveratrol administration and acute swimming exercise resulted in changes in zinc, iron, magnesium, selenium, molybdenum levels in kidney tissue, iron and calcium levels in heart tissue, and zinc, iron and molybdenum levels in liver tissue (p<0.05). The results of study, which revealed that resveratrol administration caused changes in element metabolism in some tissues of rats both during and independently of exercise, can be presented as the first and original finding based on med-line scans.

Keywords

Acute swimming exercise, Element metabolism, Resveratrol application, Rat

Supporting Institution

Scientific Research Projects Coordinatorship of Selcuk University

Project Number

SUBAPK; project no. 1420132013

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